Thermodynamic profiles and nuclear magnetic resonance studies of oligonucleotide duplexes containing single diastereomeric spiroiminodihydantoin lesions.

Thermodynamic profiles and nuclear magnetic resonance studies of oligonucleotide duplexes containing single diastereomeric spiroiminodihydantoin lesions.

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http://www.wikidata.org/entity/Q30586686
Genome and cancer single nucleotide polymorphisms of the human NEIL1 DNA glycosylase: Activity, structure, and the effect of editingReconciliation of chemical, enzymatic, spectroscopic and computational data to assign the absolute configuration of the DNA base lesion spiroiminodihydantoin.Base and Nucleotide Excision Repair of Oxidatively Generated Guanine Lesions in DNA.Effect of Base-Pairing Partner on the Thermodynamic Stability of the Diastereomeric Spiroiminodihydantoin Lesion.Guanine oxidation product 5-carboxamido-5-formamido-2-iminohydantoin induces mutations when bypassed by DNA polymerases and is a substrate for base excision repair.Structural destabilization of DNA duplexes containing single-base lesions investigated by nanopore measurementsEndonuclease and Exonuclease Activities on Oligodeoxynucleotides Containing Spiroiminodihydantoin Depend on the Sequence Context and the Lesion Stereochemistry.Reverse Transcription Past Products of Guanine Oxidation in RNA Leads to Insertion of A and C opposite 8-Oxo-7,8-dihydroguanine and A and G opposite 5-Guanidinohydantoin and Spiroiminodihydantoin Diastereomers.The Nonbulky DNA Lesions Spiroiminodihydantoin and 5-Guanidinohydantoin Significantly Block Human RNA Polymerase II Elongation in Vitro.Removal of oxidatively generated DNA damage by overlapping repair pathways.Repair-Resistant DNA Lesions.Computational studies of electronic circular dichroism spectra predict absolute configuration assignments for the guanine oxidation product 5-carboxamido-5-formamido-2-iminohydantoin.8-Oxo-7,8-dihydro-2'-deoxyguanosine and abasic site tandem lesions are oxidation prone yielding hydantoin products that strongly destabilize duplex DNA.Interrogation of Base Pairing of the Spiroiminodihydantoin Diastereomers Using the α-Hemolysin Latch.The Human DNA glycosylases NEIL1 and NEIL3 Excise Psoralen-Induced DNA-DNA Cross-Links in a Four-Stranded DNA Structure.Investigation of the Melting Behavior of DNA Three-Way Junctions in the Closed and Open States.
P2860

Thermodynamic profiles and nuclear magnetic resonance studies of oligonucleotide duplexes containing single diastereomeric spiroiminodihydantoin lesions.

Item
http://www.wikidata.org/entity/Q30586686
description
2013 nî lūn-bûn
@nan
2013 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Thermodynamic profiles and nuc ...... spiroiminodihydantoin lesions.
@ast
Thermodynamic profiles and nuc ...... spiroiminodihydantoin lesions.
@en
type
label
Thermodynamic profiles and nuc ...... spiroiminodihydantoin lesions.
@ast
Thermodynamic profiles and nuc ...... spiroiminodihydantoin lesions.
@en
prefLabel
Thermodynamic profiles and nuc ...... spiroiminodihydantoin lesions.
@ast
Thermodynamic profiles and nuc ...... spiroiminodihydantoin lesions.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
Thermodynamic profiles and nuc ...... spiroiminodihydantoin lesions.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932