Uncoupling lifespan and healthspan in Caenorhabditis elegans longevity mutants. - Wikidata - wikimedia - TriplyDB

Uncoupling lifespan and healthspan in Caenorhabditis elegans longevity mutants.

Uncoupling lifespan and healthspan in Caenorhabditis elegans longevity mutants.

http://www.wikidata.org/entity/Q30619301

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Geroscience approaches to increase healthspan and slow aging Developing criteria for evaluation of geroprotectors as a key stage toward translation to the clinic Intestinal Autophagy Improves Healthspan and Longevity in C. elegans during Dietary Restriction C. elegans maximum velocity correlates with healthspan and is maintained in worms with an insulin receptor mutation.A size threshold governs Caenorhabditis elegans developmental progression Genes of susceptibility to early neurodegenerative changes in the rat retina and brain: analysis by means of congenic strains HandKAchip - Hands-free killing assay on a chip.A network approach to discerning the identities of C. elegans in a free moving population.Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway Physiological frailty index (PFI): quantitative in-life estimate of individual biological age in mice Behavioral Phenotyping and Pathological Indicators of Parkinson's Disease in C. elegans Models.Coronary artery calcifications predict long term cardiovascular events in non diabetic Caucasian hemodialysis patients.High-glucose diets have sex-specific effects on aging in C. elegans: toxic to hermaphrodites but beneficial to males.Insulin signalling mediates the response to male-induced harm in female Drosophila melanogaster Asynchrony of senescence among phenotypic traits in a wild mammal population.Healthspan Pharmacology.SREBP and MDT-15 protect C. elegans from glucose-induced accelerated aging by preventing accumulation of saturated fat Atypical antidepressants extend lifespan of Caenorhabditis elegans by activation of a non-cell-autonomous stress response.Central insulin-like growth factor-1 (IGF-1) restores whole-body insulin action in a model of age-related insulin resistance and IGF-1 decline.Age-Related Phasic Patterns of Mitochondrial Maintenance in Adult Caenorhabditis elegans Neurons.SKN-1/Nrf, stress responses, and aging in Caenorhabditis elegans.The Somatotropic Axis in Human Aging: Framework for the Current State of Knowledge and Future Research Mechanosensory Neuron Aging: Differential Trajectories with Lifespan-Extending Alaskan Berry and Fungal Treatments in Caenorhabditis elegans A cross-sectional study of male and female C57BL/6Nia mice suggests lifespan and healthspan are not necessarily correlated.An aging-independent replicative lifespan in a symmetrically dividing eukaryote.The Companion Dog as a Model for the Longevity Dividend.Indoles from commensal bacteria extend healthspan.Geroprotectors: A Unified Concept and Screening Approaches.Healthspan and longevity can be extended by suppression of growth hormone signaling.Geroscience: Addressing the mismatch between its exciting research opportunities, its economic imperative and its current funding crisis.Assessing Health Span in Caenorhabditis elegans: Lessons From Short-Lived Mutants.Age-associated vulval integrity is an important marker of nematode healthspan.Scavengers of reactive γ-ketoaldehydes extend Caenorhabditis elegans lifespan and healthspan through protein-level interactions with SIR-2.1 and ETS-7.Suppression of transcriptional drift extends C. elegans lifespan by postponing the onset of mortality.Ageing with elegans: a research proposal to map healthspan pathways.How a Mutation that Slows Aging Can Also Disproportionately Extend End-of-Life Decrepitude.Molecular and genomic sciences in health: apply the established rules of evidence.Effective drug combination for Caenorhabditis elegans nematodes discovered by output-driven feedback system control technique.Aging causes decreased resistance to multiple stresses and a failure to activate specific stress response pathways Loss of Sphingosine Kinase Alters Life History Traits and Locomotor Function in Caenorhabditis elegans.

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P2860

Uncoupling lifespan and healthspan in Caenorhabditis elegans longevity mutants.

http://www.wikidata.org/entity/Q30619301

description

2015 nî lūn-bûn

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2015 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2015 թվականի հունվարին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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name

Uncoupling lifespan and healthspan in Caenorhabditis elegans longevity mutants.

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Uncoupling lifespan and healthspan in Caenorhabditis elegans longevity mutants.

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type

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Uncoupling lifespan and healthspan in Caenorhabditis elegans longevity mutants.

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Uncoupling lifespan and healthspan in Caenorhabditis elegans longevity mutants.

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prefLabel

Uncoupling lifespan and healthspan in Caenorhabditis elegans longevity mutants.

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Uncoupling lifespan and healthspan in Caenorhabditis elegans longevity mutants.

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PNAS.1412192112

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Proceedings of the National Academy of Sciences of the United States of America

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Uncoupling lifespan and healthspan in Caenorhabditis elegans longevity mutants

@en

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Lihua J Zhu

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P2860

CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans

Evolutionary conservation of the clk-1-dependent mechanism of longevity: loss of mclk1 increases cellular fitness and lifespan in mice

Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation

A C. elegans mutant that lives twice as long as wild type

Metformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1

A comparative study of fat storage quantitation in nematode Caenorhabditis elegans using label and label-free methods

Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans

Age- and calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans.

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E277-86

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10.1073/PNAS.1412192112

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Heidi A Tissenbaum

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Caenorhabditis elegans

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