Pyruvate carboxylase is critical for non-small-cell lung cancer proliferation. - Wikidata - wikimedia - TriplyDB

Pyruvate carboxylase is critical for non-small-cell lung cancer proliferation.

Pyruvate carboxylase is critical for non-small-cell lung cancer proliferation.

http://www.wikidata.org/entity/Q30619793

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Metabolomics: Bridging the Gap between Pharmaceutical Development and Population Health Fundamentals of cancer metabolism MicroRNAs and oncogenic transcriptional regulatory networks controlling metabolic reprogramming in cancers Mitochondria in Cancer Energy Metabolism: Culprits or Bystanders?Integration of Mitochondrial Targeting for Molecular Cancer Therapeutics Metabolic pathways promoting cancer cell survival and growth Proteomic analysis of pRb loss highlights a signature of decreased mitochondrial oxidative phosphorylation A neuronal network of mitochondrial dynamics regulates metastasis.Estimation of flux ratios without uptake or release data: Application to serine and methionine metabolism.Intratumor Heterogeneity in Primary Kidney Cancer Revealed by Metabolic Profiling of Multiple Spatially Separated Samples within Tumors.From Krebs to clinic: glutamine metabolism to cancer therapy.Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism In vivo analysis of lung cancer metabolism: nothing like the real thing.Pyruvate Carboxylase Is Up-Regulated in Breast Cancer and Essential to Support Growth and Invasion of MDA-MB-231 Cells Metabolic plasticity maintains proliferation in pyruvate dehydrogenase deficient cells Signaling through the Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Axis Is Responsible for Aerobic Glycolysis mediated by Glucose Transporter in Epidermal Growth Factor Receptor (EGFR)-mutated Lung Adenocarcinoma.Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis.Mass spectrometry analysis shows the biosynthetic pathways supported by pyruvate carboxylase in highly invasive breast cancer cells.Cancer's Fuel Choice: New Flavors for a Picky Eater The Emerging Hallmarks of Cancer Metabolism Metabolic Heterogeneity in Human Lung Tumors.Pyruvate Carboxylase Activates the RIG-I-like Receptor-Mediated Antiviral Immune Response by Targeting the MAVS signalosome.Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer Beyond antioxidant genes in the ancient Nrf2 regulatory network.Applications of NMR spectroscopy to systems biochemistry.Metabolomics: an emerging but powerful tool for precision medicine Metabolic requirements for cancer cell proliferation Distinctly perturbed metabolic networks underlie differential tumor tissue damages induced by immune modulator β-glucan in a two-case ex vivo non-small-cell lung cancer study.A distinct holoenzyme organization for two-subunit pyruvate carboxylase.Inhibition of c-FLIPL expression by miRNA-708 increases the sensitivity of renal cancer cells to anti-cancer drugs.Exogenous pyruvate facilitates cancer cell adaptation to hypoxia by serving as an oxygen surrogate.Divergent in vitro/in vivo responses to drug treatments of highly aggressive NIH-Ras cancer cells: a PET imaging and metabolomics-mass-spectrometry study.Tumour microenvironment factors shaping the cancer metabolism landscape.Altered Mitochondrial Signalling and Metabolism in Cancer.Metabolic interactions in cancer: cellular metabolism at the interface between the microenvironment, the cancer cell phenotype and the epigenetic landscape.Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase.The BRAF Inhibitor Vemurafenib Activates Mitochondrial Metabolism and Inhibits Hyperpolarized Pyruvate-Lactate Exchange in BRAF-Mutant Human Melanoma Cells.Malonate as a ROS product is associated with pyruvate carboxylase activity in acute myeloid leukaemia cells.Preclinical models for interrogating drug action in human cancers using Stable Isotope Resolved Metabolomics (SIRM).Mitochondrial pyruvate carrier function and cancer metabolism.

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P2860

Pyruvate carboxylase is critical for non-small-cell lung cancer proliferation.

http://www.wikidata.org/entity/Q30619793

description

2015 nî lūn-bûn

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2015 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2015 թվականի հունվարին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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name

Pyruvate carboxylase is critical for non-small-cell lung cancer proliferation.

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Pyruvate carboxylase is critical for non-small-cell lung cancer proliferation.

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type

label

Pyruvate carboxylase is critical for non-small-cell lung cancer proliferation.

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Pyruvate carboxylase is critical for non-small-cell lung cancer proliferation.

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prefLabel

Pyruvate carboxylase is critical for non-small-cell lung cancer proliferation.

@ast

Pyruvate carboxylase is critical for non-small-cell lung cancer proliferation.

@en

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P1433

Journal of Clinical Investigation

P1476

Pyruvate carboxylase is critical for non-small-cell lung cancer proliferation.

@en

P2093

Andrew N Lane

http://www.w3.org/2001/XMLSchema#string

Donald M Miller

http://www.w3.org/2001/XMLSchema#string

Jun Yan

http://www.w3.org/2001/XMLSchema#string

Katherine Sellers

http://www.w3.org/2001/XMLSchema#string

Mariia O Yuneva

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Matthew P Fox

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Michael Bousamra

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Rahul Deshpande

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Richard M Higashi

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Stephen P Slone

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P2860

Hallmarks of Cancer: The Next Generation

Inhibition of glutaminase expression by antisense mRNA decreases growth and tumourigenicity of tumour cells

Understanding the Warburg effect: the metabolic requirements of cell proliferation

On the Origin of Cancer Cells

The tumor metabolome

Metabolic profiling identifies lung tumor responsiveness to erlotinib

Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

Energy metabolism in astrocytes: high rate of oxidative metabolism and spatiotemporal dependence on glycolysis/glycogenolysis.

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687-698

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10.1172/JCI72873

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2

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125

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2015-01-20T00:00:00Z

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271332493

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25607840

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4319441

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