Hematin polymerization assay as a high-throughput screen for identification of new antimalarial pharmacophores.
about
Hemozoin and antimalarial drug discoveryIdentification of β-hematin inhibitors in a high-throughput screening effort reveals scaffolds with in vitro antimalarial activity.Lipophilic mediated assays for beta-hematin inhibitors.In vivo antimalarial activity of the endophytic actinobacteria, Streptomyces SUK 10.Identification and SAR Evaluation of Hemozoin-Inhibiting Benzamides Active against Plasmodium falciparum.Colorimetric high-throughput screen for detection of heme crystallization inhibitors.Recent advances in the discovery of haem-targeting drugs for malaria and schistosomiasis.Prodrugs of bisthiazolium salts are orally potent antimalarialsMalaria and iron: history and review.Gancidin W, a potential low-toxicity antimalarial agent isolated from an endophytic Streptomyces SUK10Plasmodium cell biology should inform strategies used in the development of antimalarial transmission-blocking drugs.Plasmodium falciparum gametocytes: with a view to a kill.High-Throughput Screening and Prediction Model Building for Novel Hemozoin Inhibitors Using Physicochemical Properties.Growth of Large Hematin Crystals in Biomimetic Solutions.Use of the NP-40 detergent-mediated assay in discovery of inhibitors of beta-hematin crystallization.Neutral lipids associated with haemozoin mediate efficient and rapid β-haematin formation at physiological pH, temperature and ionic compositionA simple and inexpensive haemozoin-based colorimetric method to evaluate anti-malarial drug activity.Cytostatic versus cytocidal activities of chloroquine analogues and inhibition of hemozoin crystal growth.Simple colorimetric inhibition assay of heme crystallization for high-throughput screening of antimalarial compounds.Development in Assay Methods for in Vitro Antimalarial Drug Efficacy Testing: A Systematic Review.Identification and Mechanistic Evaluation of Hemozoin-Inhibiting Triarylimidazoles Active against Plasmodium falciparum.
P2860
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P2860
Hematin polymerization assay as a high-throughput screen for identification of new antimalarial pharmacophores.
description
2000 nî lūn-bûn
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2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հոտեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
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2000年论文
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name
Hematin polymerization assay a ...... w antimalarial pharmacophores.
@ast
Hematin polymerization assay a ...... w antimalarial pharmacophores.
@en
type
label
Hematin polymerization assay a ...... w antimalarial pharmacophores.
@ast
Hematin polymerization assay a ...... w antimalarial pharmacophores.
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prefLabel
Hematin polymerization assay a ...... w antimalarial pharmacophores.
@ast
Hematin polymerization assay a ...... w antimalarial pharmacophores.
@en
P2093
P2860
P1476
Hematin polymerization assay a ...... w antimalarial pharmacophores.
@en
P2093
Hofheinz W
Kitsuji-Shirane M
Kurosawa Y
Masciadri R
P2860
P304
P356
10.1128/AAC.44.10.2638-2644.2000
P407
P577
2000-10-01T00:00:00Z