Insights into TREM2 biology by network analysis of human brain gene expression data. - Wikidata - wikimedia - TriplyDB

Insights into TREM2 biology by network analysis of human brain gene expression data.

Insights into TREM2 biology by network analysis of human brain gene expression data.

http://www.wikidata.org/entity/Q30655347

about

Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease A missense mutation in KCTD17 causes autosomal dominant myoclonus-dystonia The amyloid hypothesis of Alzheimer's disease at 25 years TREM2 in CNS homeostasis and neurodegenerative disease Microglia recapitulate a hematopoietic master regulator network in the aging human frontal cortex Beta-Amyloid Precursor Protein (βAPP) Processing in Alzheimer's Disease (AD) and Age-Related Macular Degeneration (AMD)Tau overexpression impacts a neuroinflammation gene expression network perturbed in Alzheimer's disease Convergent genetic and expression data implicate immunity in Alzheimer's disease An additional k-means clustering step improves the biological features of WGCNA gene co-expression networks.Altered microglial response to Aβ plaques in APPPS1-21 mice heterozygous for TREM2.Late onset Alzheimer's disease genetics implicates microglial pathways in disease risk.esyN: network building, sharing and publishing Gene co-expression networks shed light into diseases of brain iron accumulation.Frontobasal gray matter loss is associated with the TREM2 p.R47H variant Prostaglandin E2 receptor subtype 2 regulation of scavenger receptor CD36 modulates microglial Aβ42 phagocytosis.Genetic evidence for a pathogenic role for the vitamin D3 metabolizing enzyme CYP24A1 in multiple sclerosis TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models.Neuronal DNA damage response-associated dysregulation of signalling pathways and cholesterol metabolism at the earliest stages of Alzheimer-type pathology More evidence for association of a rare TREM2 mutation (R47H) with Alzheimer's disease risk.Insights from cerebellar transcriptomic analysis into the pathogenesis of ataxia.microRNA-34a-Mediated Down-Regulation of the Microglial-Enriched Triggering Receptor and Phagocytosis-Sensor TREM2 in Age-Related Macular Degeneration The TREM2-DAP12 signaling pathway in Nasu-Hakola disease: a molecular genetics perspective.Microglia-targeted stem cell therapies for Alzheimer disease: A preclinical data review.Systems biology and gene networks in neurodevelopmental and neurodegenerative disorders.TREM2 upregulation correlates with 5-hydroxymethycytosine enrichment in Alzheimer's disease hippocampus Cerebrospinal fluid soluble TREM2 in aging and Alzheimer's disease eComment. Genetics and delirium after heart surgery.Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing.Microglial dysfunction in brain aging and Alzheimer's disease Early changes in CSF sTREM2 in dominantly inherited Alzheimer's disease occur after amyloid deposition and neuronal injury.Alzheimer's disease genetics: from the bench to the clinic.Frontotemporal dementia: insights into the biological underpinnings of disease through gene co-expression network analysis TREM2 in Neurodegenerative Diseases.TREM2-Ligand Interactions in Health and Disease.A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression.Increased DNA methylation near TREM2 is consistently seen in the superior temporal gyrus in Alzheimer's disease brain.Deficits in the miRNA-34a-regulated endogenous TREM2 phagocytosis sensor-receptor in Alzheimer's disease (AD); an update TREM2 signaling, miRNA-34a and the extinction of phagocytosis.Defining Trends in Global Gene Expression in Arabian Horses with Cerebellar Abiotrophy.Transcriptome profiling of equine vitamin E deficient neuroaxonal dystrophy identifies upregulation of liver X receptor target genes.

P2860

Q24312938-518D9E39-C7D2-47C7-A102-E054E3534BFB Q24337555-3F6432F0-546F-4D1B-A6D6-4E1EB96359C4 Q26749528-D9C2C1BE-EED5-4AA3-B600-992EA9366765 Q26785919-EE821D05-7243-46BC-8376-96B11CDD4326 Q27011558-A753F844-0E6B-4196-86F9-264416BF9F5A Q27021938-E9D90F85-A1F1-4E14-A2BB-664652D118A7 Q27313627-38A7A934-3AA3-49AC-A026-BED0C9CBEA65 Q30881547-C93C2EA6-8928-4183-AD26-F770B7CAEBB3 Q33555901-BD3D35DE-0D7C-47EB-859B-146ADE4936E4 Q33727947-6FCB7E8C-B685-406A-AE95-0D2288232D87 Q33733863-EA8E4678-FA9A-4902-96F8-4BE27029E7D0 Q34436467-4D355846-0533-43F4-A0A2-89D5C9ACE4FB Q34506653-67BE56F8-D463-4718-85BC-A3E9A706FB0C Q34620183-94CF6157-9186-4DE3-8B94-A23A588DD97D Q34780834-53924076-D983-477B-9A75-1347D6594EA4 Q34781864-8C8DD080-6634-4F64-B1A1-CBBA3CD064D1 Q35161472-CE47A9F1-6009-40A2-894B-E22F47C01757 Q35669877-2F0921F3-5323-43EF-ACC2-5F040F03AE80 Q35733491-CA35CC2F-E512-4F6F-BE8C-022DE4CF3455 Q35747030-C62F3F2B-B14B-46F5-838D-623CD5EF1FA7 Q35947548-0681A94B-AD51-44E3-A5BA-2BB98CD3F513 Q36161131-97BB8C76-2D17-47A2-8067-E3A7A9285B7D Q36413131-5DCF748D-905A-41A1-BDB6-F5D27D72A273 Q36424672-3D3B690C-9210-45D2-9629-7FD91E31FF00 Q36765735-ED948010-6A05-4F76-8501-95E83F8E6A49 Q36846582-92D8BBFA-007B-4545-90A7-D370E193F336 Q37247424-4C04D33C-7715-4667-B5E4-7C19723C3E10 Q37615837-3797DA22-50BE-49D7-A8DD-489DE6DA6199 Q37678533-F3A45C4F-75BE-45AE-A70B-5609ECA7DC1A Q37743591-DBA2CE1F-96A5-44B6-BEA9-B7571140B254 Q38225911-C69A81F8-9E5B-404C-AF1F-48B5AD4DCA70 Q38611043-A980DA07-61BA-4E27-9D63-EE013AF36DFF Q38646212-55887569-736C-49CB-B3E1-5736E3A401E1 Q38692159-82F85554-1873-4051-807F-236F4922F1F7 Q39112446-E58CEFE1-E032-46BE-B2CB-33FFE0CB2BE4 Q39492108-A0128B95-BEA5-4E8F-A534-47BB8DFA9EEA Q40781085-322700A9-B216-4437-B141-910EE508D233 Q42576005-D3991E2F-B424-4528-B676-931103143CDE Q42774626-6A7C9239-DCA8-4746-804B-EEA46C9D50D3 Q46932523-615E47BF-1F5D-447E-8CCC-13C76EB8890A

P2860

Insights into TREM2 biology by network analysis of human brain gene expression data.

http://www.wikidata.org/entity/Q30655347

description

2013 nî lūn-bûn

@nan

2013 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

Insights into TREM2 biology by network analysis of human brain gene expression data.

@ast

Insights into TREM2 biology by network analysis of human brain gene expression data.

@en

type

label

Insights into TREM2 biology by network analysis of human brain gene expression data.

@ast

Insights into TREM2 biology by network analysis of human brain gene expression data.

@en

prefLabel

Insights into TREM2 biology by network analysis of human brain gene expression data.

@ast

Insights into TREM2 biology by network analysis of human brain gene expression data.

@en

P1433

Q30655347-A11EAFEF-D9D7-4E9D-980F-FDCE238E414E

P1476

Q30655347-4EDA0A4C-4F29-4100-8977-91BC283B1FAD

P2093

Q30655347-214540D6-4996-4B89-A420-121B717A0225

Q30655347-B4C35085-BB99-4B7C-887E-5791453960DB

Q30655347-D841B528-7BCD-4F4D-B1D8-6794F4455BE7

Q30655347-EE364580-2810-48F3-BAFF-767125C44337

P2860

Q30655347-0035D485-DF73-4F44-BDE7-5D122DBB2F45

Q30655347-015A2A1B-42B7-49FC-AD97-1287C1BD2FE9

Q30655347-01A1FAF2-0D02-4C16-B2E2-69BFB9CC783C

Q30655347-038AC849-4555-4A4D-86A8-0EC3FD918F24

Q30655347-0AD96E7B-CCAE-478C-BEA5-48258947C94B

Q30655347-0C5EBE8E-6F19-4C73-BCD1-CD8419CB2251

Q30655347-0CE7B30B-FB3B-4331-9CB8-60BD2423237D

Q30655347-1295340F-F08D-44BC-A578-FBF5228AC350

Q30655347-16D96506-1BE6-47AB-A9AB-70FF4724EE18

Q30655347-170C4495-CF38-40C4-A470-D77331F2DF9B

P304

Q30655347-BC7E6B1D-86A5-45FB-B549-E78EC459A064

P31

Q30655347-1323725F-8C2E-4F07-8E44-C0725BC111F9

P356

Q30655347-DF41886F-8F5C-445E-8416-288B139B208A

P433

Q30655347-70CB34F5-4FCC-401C-A1B4-E7048A738C9A

P478

Q30655347-08727BA4-31AC-4031-9075-5562595B2ADC

P50

Q30655347-69BCF683-D395-4AA0-B80A-F859F39FF1A8

Q30655347-7636AEDB-C2DE-4BFF-9E4A-74DFE86B1062

Q30655347-8142C046-9B7D-4E62-A1C1-34B9BECD08FD

Q30655347-83705D81-6159-4619-8ACC-E27BCE7997BF

Q30655347-846707F3-CC92-4BB4-A4C2-A2DC139400C1

Q30655347-95591E6A-682F-4752-81B8-EB2B26544E08

Q30655347-9D80444D-E360-4EB1-9070-EDA5AE91D35F

Q30655347-A20D4FFF-2A53-4C8F-9CE4-DB3D95024175

P577

Q30655347-FA83ABC1-D422-4475-8B35-8BB07A8463C2

P5875

Q30655347-CB106CD6-8237-4D59-9364-849DA4BF1056

P698

Q30655347-0BB8EF32-A179-447E-81CF-D2C34A9F9B5D

P932

Q30655347-ED188F19-98E8-4678-B82B-F02CF7293DC8

P356

J.NEUROBIOLAGING.2013.05.001

P1433

Neurobiology of Aging

P1476

Insights into TREM2 biology by network analysis of human brain gene expression data.

@en

P2093

Adam P Levine

http://www.w3.org/2001/XMLSchema#string

Colin Smith

http://www.w3.org/2001/XMLSchema#string

Jennifer M Pocock

http://www.w3.org/2001/XMLSchema#string

Paola Forabosco

http://www.w3.org/2001/XMLSchema#string

P2860

WGCNA: an R package for weighted correlation network analysis

TREM2 Variants in Alzheimer's Disease

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

Neuroscience in the era of functional genomics and systems biology

Hem-1 complexes are essential for Rac activation, actin polymerization, and myosin regulation during neutrophil chemotaxis

DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation

KEGG: kyoto encyclopedia of genes and genomes

Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype

Cluster analysis and display of genome-wide expression patterns

Dedicator of cytokinesis 8 is disrupted in two patients with mental retardation and developmental disabilities

P304

2699-2714

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.NEUROBIOLAGING.2013.05.001

http://www.w3.org/2001/XMLSchema#string

P433

12

http://www.w3.org/2001/XMLSchema#string

P478

34

http://www.w3.org/2001/XMLSchema#string

P50

Michael E. Weale

Daniah Trabzuni

Adaikalavan Ramasamy

John Anthony Hardy

P577

2013-07-12T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

249646938

http://www.w3.org/2001/XMLSchema#string

P698

23855984

http://www.w3.org/2001/XMLSchema#string

P932

3988951

http://www.w3.org/2001/XMLSchema#string