Combinatorial library cloning of human antibodies to Streptococcus pneumoniae capsular polysaccharides: variable region primary structures and evidence for somatic mutation of Fab fragments specific for capsular serotypes 6B, 14, and 23F
about
Correlation of molecular characteristics, isotype, and in vitro functional activity of human antipneumococcal monoclonal antibodies.Recurrent variable region gene usage and somatic mutation in the human antibody response to the capsular polysaccharide of Streptococcus pneumoniae type 23F.Somatic hypermutation and diverse immunoglobulin gene usage in the human antibody response to the capsular polysaccharide of Streptococcus pneumoniae Type 6B.A peptide mimotope of type 8 pneumococcal capsular polysaccharide induces a protective immune response in miceImmune response to pneumococcal polysaccharides 4 and 14 in elderly and young adults: analysis of the variable light chain repertoire.Immune response to pneumococcal polysaccharides 4 and 14 in elderly and young adults: analysis of the variable heavy chain repertoireDiversity of the antibody response to tetanus toxoid: comparison of hybridoma library to phage display libraryPriming for immunologic memory in adults by meningococcal group C conjugate vaccination.Dendritic cell-derived exosomes express a Streptococcus pneumoniae capsular polysaccharide type 14 cross-reactive antigen that induces protective immunoglobulin responses against pneumococcal infection in mice.Phenotypic analysis of pneumococcal polysaccharide-specific B cells.Immune Responses to pneumococcal vaccines in children and adults: Rationale for age-specific vaccination.Differential idiotype utilization for the in vivo type 14 capsular polysaccharide-specific Ig responses to intact Streptococcus pneumoniae versus a pneumococcal conjugate vaccineParatope diversity in the human antibody response to Bacillus anthracis protective antigen.Codon insertion and deletion functions as a somatic diversification mechanism in human antibody repertoires.Somatic diversification in the absence of antigen-driven responses is the hallmark of the IgM+ IgD+ CD27+ B cell repertoire in infantsThe immune response to pneumococcal polysaccharides 14 and 23F among elderly individuals consists predominantly of switched memory B cells.The capsule of Bacillus anthracis behaves as a thymus-independent type 2 antigen.Mechanisms underlying in vivo polysaccharide-specific immunoglobulin responses to intact extracellular bacteria.Restricted, canonical, stereotyped and convergent immunoglobulin responses.Rare, high-affinity anti-pathogen antibodies from human repertoires, discovered using microfluidics and molecular genomics.Ageing of the B-cell repertoire.Human blood IgM "memory" B cells are circulating splenic marginal zone B cells harboring a prediversified immunoglobulin repertoire.Natural human antibodies to pneumococcus have distinctive molecular characteristics and protect against pneumococcal disease
P2860
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P2860
Combinatorial library cloning of human antibodies to Streptococcus pneumoniae capsular polysaccharides: variable region primary structures and evidence for somatic mutation of Fab fragments specific for capsular serotypes 6B, 14, and 23F
description
2001 nî lūn-bûn
@nan
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Combinatorial library cloning ...... ular serotypes 6B, 14, and 23F
@ast
Combinatorial library cloning ...... ular serotypes 6B, 14, and 23F
@en
type
label
Combinatorial library cloning ...... ular serotypes 6B, 14, and 23F
@ast
Combinatorial library cloning ...... ular serotypes 6B, 14, and 23F
@en
prefLabel
Combinatorial library cloning ...... ular serotypes 6B, 14, and 23F
@ast
Combinatorial library cloning ...... ular serotypes 6B, 14, and 23F
@en
P2093
P2860
P1476
Combinatorial library cloning ...... ular serotypes 6B, 14, and 23F
@en
P2093
P2860
P304
P356
10.1128/IAI.69.2.853-864.2001
P407
P577
2001-02-01T00:00:00Z