Potent second generation vinyl sulfonamide inhibitors of the trypanosomal cysteine protease cruzain.
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Identification and Optimization of Inhibitors of Trypanosomal Cysteine Proteases: Cruzain, Rhodesain, and TbCatBIn Vitro and In Vivo Studies of the Trypanocidal Properties of WRR-483 against Trypanosoma cruziStructural Basis for Inhibition of Cathepsin B Drug Target from the Human Blood Fluke, Schistosoma mansoniA novel Entamoeba histolytica cysteine proteinase, EhCP4, is key for invasive amebiasis and a therapeutic target.Quantitative analyses of aggregation, autofluorescence, and reactivity artifacts in a screen for inhibitors of a thiol proteaseCongopain from Trypanosoma congolense: drug target and vaccine candidate.Structure-activity relationships for inhibition of cysteine protease activity and development of Plasmodium falciparum by peptidyl vinyl sulfones.Synthesis of a sugar-based thiosemicarbazone series and structure-activity relationship versus the parasite cysteine proteases rhodesain, cruzain, and Schistosoma mansoni cathepsin B1.Synthesis and Evaluation of Oxyguanidine Analogues of the Cysteine Protease Inhibitor WRR-483 against Cruzain.Chemical-biological characterization of a cruzain inhibitor reveals a second target and a mammalian off-target.Synthesis of macrocyclic trypanosomal cysteine protease inhibitors.Angiotensin-converting enzyme limits inflammation elicited by Trypanosoma cruzi cysteine proteases: a peripheral mechanism regulating adaptive immunity via the innate kinin pathway.Trypanocidal drugs: mechanisms, resistance and new targets.Synthetic Medicinal Chemistry in Chagas' Disease: Compounds at The Final Stage of "Hit-To-Lead" Phase.Identification of cysteine protease inhibitors as new drug leads against Naegleria fowleri.Cysteine protease inhibitors as potential antiparasitic agents
P2860
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P2860
Potent second generation vinyl sulfonamide inhibitors of the trypanosomal cysteine protease cruzain.
description
2001 nî lūn-bûn
@nan
2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Potent second generation vinyl ...... mal cysteine protease cruzain.
@ast
Potent second generation vinyl ...... mal cysteine protease cruzain.
@en
type
label
Potent second generation vinyl ...... mal cysteine protease cruzain.
@ast
Potent second generation vinyl ...... mal cysteine protease cruzain.
@en
prefLabel
Potent second generation vinyl ...... mal cysteine protease cruzain.
@ast
Potent second generation vinyl ...... mal cysteine protease cruzain.
@en
P2093
P1476
Potent second generation vinyl ...... mal cysteine protease cruzain.
@en
P2093
Alvarez-Hernandez A
Knapp-Reed B
McKerrow JH
P304
P356
10.1016/S0960-894X(01)00566-2
P407
P577
2001-10-01T00:00:00Z