Detection of oncogenic IDH1 mutations using magnetic resonance spectroscopy of 2-hydroxyglutarate. - Wikidata - wikimedia - TriplyDB

Detection of oncogenic IDH1 mutations using magnetic resonance spectroscopy of 2-hydroxyglutarate.

Detection of oncogenic IDH1 mutations using magnetic resonance spectroscopy of 2-hydroxyglutarate.

http://www.wikidata.org/entity/Q30664676

about

From Genetics to Epigenetics: New Perspectives in Tourette Syndrome Research Fundamentals of cancer metabolism Isocitrate dehydrogenase mutations: new opportunities for translational research Next generation sequencing of acute myeloid leukemia: influencing prognosis.In-Vivo Proton Magnetic Resonance Spectroscopy of 2-Hydroxyglutarate in Isocitrate Dehydrogenase-Mutated Gliomas: A Technical Review for Neuroradiologists Advanced magnetic resonance imaging of the physical processes in human glioblastoma.Classification of brain tumours from MR spectra: the INTERPRET collaboration and its outcomes.Detecting tumor progression in glioma: Current standards and new techniques.Isocitrate dehydrogenase 1 (IDH1) mutation in breast adenocarcinoma is associated with elevated levels of serum and urine 2-hydroxyglutarate.Intraoperative mass spectrometry mapping of an onco-metabolite to guide brain tumor surgery Accumulation of 2-hydroxyglutarate in gliomas correlates with survival: a study by 3.0-tesla magnetic resonance spectroscopy.Novel Approaches to Imaging Tumor Metabolism On the Utility of Short Echo Time (TE) Single Voxel 1H-MRS in Non-Invasive Detection of 2-Hydroxyglutarate (2HG); Challenges and Potential Improvement Illustrated with Animal Models Using MRUI and LCModel Introduction of High Throughput Magnetic Resonance T2-Weighted Image Texture Analysis for WHO Grade 2 and 3 Gliomas.TET proteins and 5-methylcytosine oxidation in hematological cancers Isocitrate dehydrogenase mutations in gliomas Elevation of Urinary 2-Hydroxyglutarate in IDH-Mutant Glioma Quantitative Imaging of D-2-Hydroxyglutarate in Selected Histological Tissue Areas by a Novel Bioluminescence Technique.Local image variance of 7 Tesla SWI is a new technique for preoperative characterization of diffusely infiltrating gliomas: correlation with tumour grade and IDH1 mutational status Proton NMR characterization of intact primary and metastatic melanoma cells in 2D & 3D cultures.PLK1 inhibition enhances temozolomide efficacy in IDH1 mutant gliomas.Study protocol of a phase IB/II clinical trial of metformin and chloroquine in patients with IDH1-mutated or IDH2-mutated solid tumours Glioma Subclassifications and Their Clinical Significance.D-2-hydroxyglutarate is essential for maintaining oncogenic property of mutant IDH-containing cancer cells but dispensable for cell growth.Improved Brain Tumor Classification by Sodium MR Imaging: Prediction of IDH Mutation Status and Tumor Progression.Replication Study: The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate.Exploiting tumor metabolism: challenges for clinical translation.Modeling mayhem: predicting invasion and proliferation kinetics in IDH1 mutant glioblastoma with mathematical models.Diagnostic value of glutamate with 2-hydroxyglutarate in magnetic resonance spectroscopy for IDH1 mutant glioma.Rise of the mutants: report from the 19th conference of the European Haematology Association, Milan, 12-15 June 2014 Comparison between Short and Long Echo Time Magnetic Resonance Spectroscopic Imaging at 3T and 7T for Evaluating Brain Metabolites in Patients with Glioma.MRI radiomics analysis of molecular alterations in low-grade gliomas.IDH mutation status trumps the Pignatti risk score as a prognostic marker in low-grade gliomas.Noninvasive IDH1 mutation estimation based on a quantitative radiomics approach for grade II glioma.Reliable diagnosis of IDH-mutant glioblastoma by 2-hydroxyglutarate detection: a study by 3-T magnetic resonance spectroscopy.Impact of gross total resection in patients with WHO grade III glioma harboring the IDH 1/2 mutation without the 1p/19q co-deletion.Genetically Defined Oligodendroglioma Is Characterized by Indistinct Tumor Borders at MRI.Anatomical location differences between mutated and wild-type isocitrate dehydrogenase 1 in low-grade gliomas.Evaluation of the microenvironmental heterogeneity in high-grade gliomas with IDH1/2 gene mutation using histogram analysis of diffusion-weighted imaging and dynamic-susceptibility contrast perfusion imaging.IDH1 Mutation and World Health Organization 2016 Diagnostic Criteria for Adult Diffuse Gliomas: Advances in Surgical Strategy.

P2860

Q26741433-37E96982-6D47-4610-B1F3-684D9E9DD257 Q26744062-28216083-720D-46B6-A5A5-7135C0072578 Q27001014-20B0061A-731A-4A9F-92EF-EF74223EC234 Q27690776-4A02EC29-54B5-4033-9435-5F4E24475C2F Q28069062-3CD4E37F-375D-400A-8CED-8B0162ADC0D8 Q30847284-752E6830-302B-4FA7-98EC-62E8F405E7B0 Q31036955-A1C4DAE5-CC7E-43E1-B2D3-20CE243F97BE Q31132701-D53D11B0-C638-41BD-945A-2037DC1E5F5A Q33699608-5896E00B-B0DC-456F-AED2-2EB4033919E9 Q34002347-1F681841-5D2B-4E7C-BE9E-A296A9DFFABD Q34539504-80657A3A-3D51-4310-8D6D-7DB29619D750 Q35700192-ED4FC1C5-CC62-4723-93C9-7C31E0A9B553 Q35907130-D2BB51F0-A637-4633-ABDC-375FF4E16799 Q36157713-3718AAA9-DF99-4EB2-B479-460C0CFD00C7 Q36197509-A2C01596-E436-4492-9171-DEDBB768DB67 Q36367409-46CC05C9-DFC1-4514-8FA8-65066BA1D6F2 Q36558431-F8E26BB3-D8C1-4226-97A1-75715030AA77 Q36656510-6788BF02-069D-499B-A668-CE54B7344908 Q37677994-9730DC94-9FAE-4D38-9FCE-1544D93F2EC4 Q37704991-B5C470ED-26E9-4A76-A688-2577CD77F466 Q37716625-9BD5C8DD-6AA9-478D-9F8F-3020AEFE74C8 Q38375735-51A2007C-ADAE-4BD4-A576-7588D77D6E57 Q38747746-ECC85B46-9806-4C9E-ACAB-B345B73793C3 Q38892705-509E9912-95EB-42AF-8121-0DFE68430F59 Q40400350-67C2D130-2357-4358-B454-5171749FCAC0 Q41026412-7C5B3B8F-F391-4475-A81A-BE6225A72D79 Q42572928-33DD4F62-D3A8-4DE3-9E11-9A90BD5D1AC0 Q42573747-2705F95F-D09B-4C24-803E-5BDCC7955928 Q42702320-49C9A6F7-DD86-4D25-A21F-2730DB68ECE9 Q42841231-FF1E0086-54A2-4C4D-9CE3-0CC6B592183C Q46664688-954AA894-2FE3-48E2-8D84-444D50D76233 Q47899803-3AE4B536-7B57-463C-A52C-433DBBF3ECAB Q48015833-E881AF96-7E71-42E7-BBBA-BEED87E8389F Q48033863-F7B80093-E0A2-43DF-A6C8-8469DDE8E26D Q48093789-85BFEBA3-5DBC-4C77-A950-444C13B6A43B Q48166117-244AE6D4-DD40-4092-BA28-F10F70625EEE Q48307043-8C66ECC4-718F-456B-B19C-6B685B348B03 Q48402369-77C1125F-D2D2-4FB7-973B-79DD06AB61D4 Q48554325-9635813E-D1C0-487E-BA88-100BA45A6C36 Q48663479-E94EB7AF-51EC-4E1A-971F-39A496178A62

P2860

Detection of oncogenic IDH1 mutations using magnetic resonance spectroscopy of 2-hydroxyglutarate.

http://www.wikidata.org/entity/Q30664676

description

2013 nî lūn-bûn

@nan

2013 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

Detection of oncogenic IDH1 mu ...... roscopy of 2-hydroxyglutarate.

@ast

Detection of oncogenic IDH1 mu ...... roscopy of 2-hydroxyglutarate.

@en

type

label

Detection of oncogenic IDH1 mu ...... roscopy of 2-hydroxyglutarate.

@ast

Detection of oncogenic IDH1 mu ...... roscopy of 2-hydroxyglutarate.

@en

prefLabel

Detection of oncogenic IDH1 mu ...... roscopy of 2-hydroxyglutarate.

@ast

Detection of oncogenic IDH1 mu ...... roscopy of 2-hydroxyglutarate.

@en

P1433

Q30664676-DD06AE42-DD77-47F0-9C3A-0B05594A67C4

P1476

Q30664676-7C97DF69-05FC-4753-A535-0745210D9AE5

P2093

Q30664676-3A1C60EA-8C0C-4966-B24F-0DBF647D7A39

Q30664676-621952B9-3F11-449A-B71F-291200F2BF78

Q30664676-7F742CF2-0F20-4838-A002-8586B8676B2B

Q30664676-81006F1D-ED8C-4CA3-A78C-E1E5A275B50C

Q30664676-91BA170B-C4AD-468E-8C16-52CD29594DCF

Q30664676-D57E518F-165E-4323-B975-CF03C5D734C5

Q30664676-E54C5EA7-8AB3-48D5-A547-72C857A4065F

P2860

Q30664676-03D439A5-F64E-4D15-8F8A-462A4BCFA006

Q30664676-06695403-C20D-4370-ABB4-E149ABEBB163

Q30664676-0A47963F-4AF9-467C-AC95-B2848309DC68

Q30664676-130F9209-D8F8-45D5-B86B-E4685F498AF1

Q30664676-15208956-2356-42B9-A128-1EF0AFEAF447

Q30664676-155AEC3F-DAC0-42DF-A5D8-80FC5BBFD237

Q30664676-1CC6CF8B-CE3C-4DC7-8F46-C3ADFDD3A54D

Q30664676-22C81C82-FE99-4385-A79F-E0DA7AF1CFFB

Q30664676-233ED449-F513-4C80-850A-06E48899533C

Q30664676-27203ED0-B3A3-456A-82B6-B5AF071C1E2A

P304

Q30664676-CCB9CBDF-C662-46F2-8379-D3F83F9C762B

P31

Q30664676-A1FE45C5-6C1A-4A61-A17F-CA4D04DCCA6E

P356

Q30664676-A670B5A0-FF78-496F-A77F-B7D0AF1F8A47

P407

Q30664676-F1807994-0E34-4F02-92FF-F3DA3F13049A

P433

Q30664676-A99BB12C-B914-4CD5-AA6C-C59818FB8CB4

P478

Q30664676-6A5C0F3B-AC94-4A8B-9715-13EB45B9959C

P50

Q30664676-992DF67D-2F5F-4CBE-A9CA-5B92FC5D0811

P577

Q30664676-A8678587-6511-4711-8058-E27EFD57DB33

P698

Q30664676-941CB5D6-7168-4061-8DDC-38FC2AEED78D

P932

Q30664676-8CF700F5-9252-4E3E-852E-EEC1C42AF4DF

P356

P1433

Journal of Clinical Investigation

P1476

Detection of oncogenic IDH1 mu ...... roscopy of 2-hydroxyglutarate.

@en

P2093

A Gregory Sorensen

http://www.w3.org/2001/XMLSchema#string

Andrew Chi

http://www.w3.org/2001/XMLSchema#string

Bruce R Rosen

http://www.w3.org/2001/XMLSchema#string

Elizabeth Gerstner

http://www.w3.org/2001/XMLSchema#string

Otto Rapalino

http://www.w3.org/2001/XMLSchema#string

Ovidiu C Andronesi

http://www.w3.org/2001/XMLSchema#string

Tracy T Batchelor

http://www.w3.org/2001/XMLSchema#string

P2860

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

Recurring mutations found by sequencing an acute myeloid leukemia genome

An integrated genomic analysis of human glioblastoma multiforme

IDH1 and IDH2 mutations in gliomas

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas

The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases

The prognostic IDH1( R132 ) mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma.

Metabolic profiles of cancer cells

P304

3659-3663

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1172/JCI67229

http://www.w3.org/2001/XMLSchema#string

P407

P433

9

http://www.w3.org/2001/XMLSchema#string

P478

123

http://www.w3.org/2001/XMLSchema#string

P50

Daniel P Cahill

P577

2013-09-03T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

23999439

http://www.w3.org/2001/XMLSchema#string

P932

3754248

http://www.w3.org/2001/XMLSchema#string