High-efficiency reprogramming of fibroblasts into cardiomyocytes requires suppression of pro-fibrotic signalling. - Wikidata - wikimedia - TriplyDB

High-efficiency reprogramming of fibroblasts into cardiomyocytes requires suppression of pro-fibrotic signalling.

High-efficiency reprogramming of fibroblasts into cardiomyocytes requires suppression of pro-fibrotic signalling.

http://www.wikidata.org/entity/Q30665262

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Cardiac fibrosis in myocardial infarction-from repair and remodeling to regeneration Bmi1 Is a Key Epigenetic Barrier to Direct Cardiac Reprogramming.Core Transcription Factors, MicroRNAs, and Small Molecules Drive Transdifferentiation of Human Fibroblasts Towards The Cardiac Cell Lineage.Reprogramming cell fates by small molecules.Direct reprogramming of fibroblasts into cardiomyocytes Transcriptional control of cardiac fibroblast plasticity.Cardiac Fibrosis: The Fibroblast Awakens Targeting Mll1 H3K4 methyltransferase activity to guide cardiac lineage specific reprogramming of fibroblasts.MiR-590 Promotes Transdifferentiation of Porcine and Human Fibroblasts Toward a Cardiomyocyte-Like Fate by Directly Repressing Specificity Protein 1.Direct Cardiac Cellular Reprogramming for Cardiac Regeneration.In situ reprogramming to transdifferentiate fibroblasts into cardiomyocytes using adenoviral vectors: Implications for clinical myocardial regeneration.Meta-Analysis of Transcriptome Regulation During Induction to Cardiac Myocyte Fate From Mouse and Human Fibroblasts.Direct cellular reprogramming for cardiac repair and regeneration.Small molecules for reprogramming and transdifferentiation.Molecular barriers to direct cardiac reprogramming.Discovery and progress of direct cardiac reprogramming.Re-patterning of H3K27me3, H3K4me3 and DNA methylation during fibroblast conversion into induced cardiomyocytes.Epigenetic Control of Reprogramming and Transdifferentiation by Histone Modifications.Improving cardiac reprogramming for heart regeneration.Assessing Cardiomyocyte Subtypes Following Transcription Factor-mediated Reprogramming of Mouse Embryonic Fibroblasts.Vitamin D attenuates myofibroblast differentiation and extracellular matrix accumulation in nasal polyp-derived fibroblasts through smad2/3 signaling pathway.Single cell qPCR reveals that additional HAND2 and microRNA-1 facilitate the early reprogramming progress of seven-factor-induced human myocytes.Single-Construct Polycistronic Doxycycline-Inducible Vectors Improve Direct Cardiac Reprogramming and Can Be Used to Identify the Critical Timing of Transgene Expression.Intrinsic remote conditioning of the myocardium as a comprehensive cardiac response to ischemia and reperfusion.Comparative Gene Expression Analyses Reveal Distinct Molecular Signatures between Differentially Reprogrammed Cardiomyocytes.Fibroblast Growth Factors and Vascular Endothelial Growth Factor Promote Cardiac Reprogramming under Defined Conditions.The downregulation of putative anticancer target BORIS/CTCFL in an addicted myeloid cancer cell line modulates the expression of multiple protein coding and ncRNA genes.Chemical Enhancement of In Vitro and In Vivo Direct Cardiac Reprogramming.Single-cell transcriptomics reconstructs fate conversion from fibroblast to cardiomyocyte.Heart regeneration for clinical application update 2016: from induced pluripotent stem cells to direct cardiac reprogramming.Regenerating the human heart: direct reprogramming strategies and their current limitations.ZNF281 enhances cardiac reprogramming by modulating cardiac and inflammatory gene expression.Nanotechnology-Based Cardiac Targeting and Direct Cardiac Reprogramming: The Betrothed.Initiating Events in Direct Cardiomyocyte Reprogramming.Specific Cell (Re-)Programming: Approaches and Perspectives.Chemical compound-based direct reprogramming for future clinical applications.S-phase Synchronization Facilitates the Early Progression of Induced-Cardiomyocyte Reprogramming through Enhanced Cell-Cycle Exit.A Loss of Function Screen of Epigenetic Modifiers and Splicing Factors during Early Stage of Cardiac Reprogramming.Direct Reprograming to Regenerate Myocardium and Repair Its Pacemaker and Conduction System.Direct Cardiac Reprogramming: Progress and Promise.

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High-efficiency reprogramming of fibroblasts into cardiomyocytes requires suppression of pro-fibrotic signalling.

http://www.wikidata.org/entity/Q30665262

description

2015 nî lūn-bûn

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2015 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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name

High-efficiency reprogramming ...... on of pro-fibrotic signalling.

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High-efficiency reprogramming ...... on of pro-fibrotic signalling.

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type

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High-efficiency reprogramming ...... on of pro-fibrotic signalling.

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High-efficiency reprogramming ...... on of pro-fibrotic signalling.

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prefLabel

High-efficiency reprogramming ...... on of pro-fibrotic signalling.

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High-efficiency reprogramming ...... on of pro-fibrotic signalling.

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Nature Communications

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High-efficiency reprogramming ...... on of pro-fibrotic signalling.

@en

P2093

Emily J Sharpe

http://www.w3.org/2001/XMLSchema#string

Kenneth L Jones

http://www.w3.org/2001/XMLSchema#string

Kunhua Song

http://www.w3.org/2001/XMLSchema#string

Mark Y Jeong

http://www.w3.org/2001/XMLSchema#string

Peter M Buttrick

http://www.w3.org/2001/XMLSchema#string

Pilar Londono

http://www.w3.org/2001/XMLSchema#string

Rebecca O'Rourke

http://www.w3.org/2001/XMLSchema#string

Timothy A McKinsey

http://www.w3.org/2001/XMLSchema#string

Yingqiong Cao

http://www.w3.org/2001/XMLSchema#string

Yuanbiao Zhao

http://www.w3.org/2001/XMLSchema#string

P2860

Regenerating the heart

Small molecules enable cardiac reprogramming of mouse fibroblasts with a single factor, Oct4.

Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities

Direct conversion of fibroblasts to functional neurons by defined factors

The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation

The basics of epithelial-mesenchymal transition

The human genome browser at UCSC

Inhibition of TGFβ signaling increases direct conversion of fibroblasts to induced cardiomyocytes

miR-1/133a clusters cooperatively specify the cardiomyogenic lineage by adjustment of myocardin levels during embryonic heart development

Myofibroblasts: trust your heart and let fate decide.

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8243

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10.1038/NCOMMS9243

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6

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Catherine Proenza

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2015-09-10T00:00:00Z

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281734455

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1024401701

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26354680

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4579788

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