Cloning of a novel G protein-coupled receptor, SLT, a subtype of the melanin-concentrating hormone receptor.
about
Identification and characterization of a second melanin-concentrating hormone receptor, MCH-2RBrain regulation of energy balance and body weight.Melanin-concentrating hormone 1 receptor-deficient mice are lean, hyperactive, and hyperphagic and have altered metabolismThe role of melanin-concentrating hormone and its receptors in energy homeostasisThe Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsConformational features of human melanin-concentrating hormone: an NMR and computational analysis.Periplakin interferes with G protein activation by the melanin-concentrating hormone receptor-1 by binding to the proximal segment of the receptor C-terminal tail.MIZIP, a highly conserved, vertebrate specific melanin-concentrating hormone receptor 1 interacting zinc-finger protein.High-throughput screening of novel antagonists on melanin-concentrating hormone receptor-1.The pharmacological properties of a novel MCH1 receptor antagonist isolated from combinatorial libraries.Synthesis and biological evaluation in vitro of a selective, high potency peptide agonist of human melanin-concentrating hormone action at human melanin-concentrating hormone receptor 1.Human immune cells express ppMCH mRNA and functional MCHR1 receptor.Melanin-concentrating hormone functions in the nervous system: food intake and stress.Identification and characterization of single-nucleotide polymorphisms in MCH-R1 and MCH-R2.Melanin-concentrating hormone and its receptors: state of the art.Melanin-concentrating hormone: a new sleep factor?Melanin-concentrating hormone neuron system: the Wide Web that controls the feeding.Therapeutic potential of melanin-concentrating hormone-1 receptor antagonists for the treatment of obesity.Human Th2 cells selectively express the orexigenic peptide, pro-melanin-concentrating hormone.Characterization of two melanin-concentrating hormone genes in zebrafish reveals evolutionary and physiological links with the mammalian MCH system.Peripheral injections of melanin-concentrating hormone receptor 1 antagonist S38151 decrease food intake and body weight in rodent obesity modelsControl of ventricular ciliary beating by the melanin concentrating hormone-expressing neurons of the lateral hypothalamus: a functional imaging survey.Electrophysiological effects of MCH on neurons in the hypothalamus.MCH receptors/gene structure-in vivo expression.Cellular models for the study of the pharmacology and signaling of melanin-concentrating hormone receptors.Recent progress in the discovery of melanin-concentrating hormone 1-receptor antagonists.The MCH(1) receptor, an anti-obesity target, is allosterically inhibited by 8-methylquinoline derivatives possessing subnanomolar binding and long residence times.Different structural requirements for melanin-concentrating hormone (MCH) interacting with rat MCH-R1 (SLC-1) and mouse B16 cell MCH-R.Microinjections of melanin concentrating hormone into the nucleus tractus solitarius of the rat elicit depressor and bradycardic responses.Interaction of melanin-concentrating hormone (MCH), neuropeptide E-I (NEI), neuropeptide G-E (NGE), and alpha-MSH with melanocortin and MCH receptors on mouse B16 melanoma cells.Chronic intracerebroventricular infusion of MCH causes obesity in mice. Melanin-concentrating hormone.Mice lacking melanin-concentrating hormone receptor 1 demonstrate increased heart rate associated with altered autonomic activity.Melanin-concentrating hormone depresses L-, N-, and P/Q-type voltage-dependent calcium channels in rat lateral hypothalamic neurons.Melanin-concentrating hormone stimulates human growth hormone secretion: a novel effect of MCH on the hypothalamic-pituitary axis.
P2860
Q24629423-728A93CE-3060-4458-95C2-0949D74FA616Q26865811-69E28D7D-2E78-4F3D-9D10-1FEF261343D9Q28204017-0972D0F3-F9AD-42F7-B95C-40ACE81CDBC6Q28708877-9E524CD3-CE61-44E6-811A-34DA51F6CEEBQ30486707-783DBEDB-E4CB-4C39-A135-8BBF877E970AQ30759680-2DCE3350-0C6C-4C05-B638-B56E6171D2D2Q33209763-E1676376-D98B-4A77-8B85-2A20A7354E2CQ33288886-3AF86593-2CA1-4CD9-BFA4-90ABB580A5ADQ33337524-E9A79B16-DBD3-49E5-ABAB-57C84D33D0DDQ33388063-5962AF23-80D4-4465-875C-A78C9016C9AFQ34113677-823DCA9F-15B2-4754-AC11-DBF676CF39ABQ34148711-83B24448-ED08-47AE-8964-FEA957EB4AA0Q34217708-08BA4F92-0AB0-4451-886D-5AEBB86FB283Q34344806-98D0E94F-235A-42EC-9378-79278568251BQ34677477-64632BD3-968E-42A5-A38B-4E35E9843244Q34822618-C9ED0498-8FD8-48BF-ADAD-560399F1AB41Q34992280-0C2760D5-DF3F-47D7-A337-B0772D161370Q35871913-ECBB0AFB-E942-4A15-81AD-0DCBC1FFD901Q35927964-9FC6A5C7-BD4C-4B1B-ADA1-0020C84FD7ABQ36189550-028A8C3C-D480-4890-977C-139BD84A7BE6Q36481257-A03AAD81-2BE5-40D6-94DD-15A7C36C07CFQ37339653-787A3A22-D593-4C8A-BCBD-F46D2AA9CF21Q37435500-01636DDD-40B1-4468-9C87-5CFF5BF489CFQ37569137-11ABFB93-C26C-42A3-B8F5-D6BC0C5A4E71Q37810288-EC832892-43E6-4354-89CD-2EDA8DDEEA98Q37865016-370DEFA9-0FD9-45D6-A796-48F8004AF398Q38265769-B5562758-882B-4075-86C6-F7FF8E58D0AAQ40656891-26192F94-673E-4A24-825D-0840C2626112Q42951893-AAB7FBEB-CAE1-4D14-A351-E13EA5549857Q43788100-213AF960-6CFC-47BD-8F6F-8F7167A7C400Q44230855-A30D82E2-5781-473A-A749-D8F690E414A7Q44886430-353ED70B-21A5-41FD-8715-24D80AD2B624Q48561716-CA4F8A22-036E-4DD7-93B3-F73F6BCFD341Q48589059-0621B29F-A948-4478-A6C9-997B07935C80
P2860
Cloning of a novel G protein-coupled receptor, SLT, a subtype of the melanin-concentrating hormone receptor.
description
2001 nî lūn-bûn
@nan
2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Cloning of a novel G protein-c ...... oncentrating hormone receptor.
@ast
Cloning of a novel G protein-c ...... oncentrating hormone receptor.
@en
type
label
Cloning of a novel G protein-c ...... oncentrating hormone receptor.
@ast
Cloning of a novel G protein-c ...... oncentrating hormone receptor.
@en
prefLabel
Cloning of a novel G protein-c ...... oncentrating hormone receptor.
@ast
Cloning of a novel G protein-c ...... oncentrating hormone receptor.
@en
P2093
P356
P1476
Cloning of a novel G protein-c ...... oncentrating hormone receptor.
@en
P2093
Nishimura O
Shimomura Y
Shintani Y
P304
P356
10.1006/BBRC.2001.4893
P407
P577
2001-05-01T00:00:00Z