Resistance to itraconazole in Aspergillus nidulans and Aspergillus fumigatus is conferred by extra copies of the A. nidulans P-450 14alpha-demethylase gene, pdmA.
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Extra copies of the Aspergillus fumigatus squalene epoxidase gene confer resistance to terbinafine: genetic approach to studying gene dose-dependent resistance to antifungals in A. fumigatusExtensive Copy Number Variation in Fermentation-Related Genes Among Saccharomyces cerevisiae Wine Strains.Evaluation of amphotericin B and chloramphenicol as alternative drugs for treatment of chytridiomycosis and their impacts on innate skin defenses.Eisosome organization in the filamentous ascomycete Aspergillus nidulansRegulatory circuitry governing fungal development, drug resistance, and disease.Identification of novel genes conferring altered azole susceptibility in Aspergillus fumigatus.The fumitremorgin gene cluster of Aspergillus fumigatus: identification of a gene encoding brevianamide F synthetase.Calcineurin controls growth, morphology, and pathogenicity in Aspergillus fumigatusMutations in Aspergillus fumigatus resulting in reduced susceptibility to posaconazole appear to be restricted to a single amino acid in the cytochrome P450 14alpha-demethylase.Multiple resistance mechanisms among Aspergillus fumigatus mutants with high-level resistance to itraconazole.Itraconazole--perspectives for the management of invasive aspergillosis.Substitutions at methionine 220 in the 14alpha-sterol demethylase (Cyp51A) of Aspergillus fumigatus are responsible for resistance in vitro to azole antifungal drugs.A novel C2H2 transcription factor that regulates gliA expression interdependently with GliZ in Aspergillus fumigatus.Novel mitogen-activated protein kinase MpkC of Aspergillus fumigatus is required for utilization of polyalcohol sugarsCryptic species and azole resistance in the Aspergillus niger complex.Identification and characterization of a novel family of selective antifungal compounds (CANBEFs) that interfere with fungal protein synthesis.Identification and characterization of haemofungin, a novel antifungal compound that inhibits the final step of haem biosynthesis.Co-Occurrence of Two Allelic Variants of CYP51 in Erysiphe necator and Their Correlation with Over-Expression for DMI Resistance.Redundant synthesis of a conidial polyketide by two distinct secondary metabolite clusters in Aspergillus fumigatus.TrpE feedback mutants reveal roadblocks and conduits toward increasing secondary metabolism in Aspergillus fumigatus.Calcineurin target CrzA regulates conidial germination, hyphal growth, and pathogenesis of Aspergillus fumigatus.Stress, drugs, and evolution: the role of cellular signaling in fungal drug resistancePlasmids for increased efficiency of vector construction and genetic engineering in filamentous fungi.F901318 represents a novel class of antifungal drug that inhibits dihydroorotate dehydrogenase.In vitro evolution of itraconazole resistance in Aspergillus fumigatus involves multiple mechanisms of resistance.Interrogation of related clinical pan-azole-resistant Aspergillus fumigatus strains: G138C, Y431C, and G434C single nucleotide polymorphisms in cyp51A, upregulation of cyp51A, and integration and activation of transposon Atf1 in the cyp51A promoterNationwide survey of in vitro activities of itraconazole and voriconazole against clinical Aspergillus fumigatus isolates cultured between 1945 and 1998.A point mutation in the 14alpha-sterol demethylase gene cyp51A contributes to itraconazole resistance in Aspergillus fumigatus.Heat shock protein 90 is required for conidiation and cell wall integrity in Aspergillus fumigatus.Multicenter study of isavuconazole MIC distributions and epidemiological cutoff values for Aspergillus spp. for the CLSI M38-A2 broth microdilution method.Aspergillus fumigatus calcipressin CbpA is involved in hyphal growth and calcium homeostasis.Lipoxygenase Activity Accelerates Programmed Spore Germination in Aspergillus fumigatus.A new Aspergillus fumigatus resistance mechanism conferring in vitro cross-resistance to azole antifungals involves a combination of cyp51A alterations.Wild-type MIC distributions and epidemiological cutoff values for the triazoles and six Aspergillus spp. for the CLSI broth microdilution method (M38-A2 document)The chitin synthase genes chsA and chsC are not required for cell wall stress responses in the human pathogen Aspergillus fumigatus.The sho1 sensor regulates growth, morphology, and oxidant adaptation in Aspergillus fumigatus but is not essential for development of invasive pulmonary aspergillosis.Molecular Tools for the Detection and Deduction of Azole Antifungal Drug Resistance Phenotypes in Aspergillus Species.An LaeA- and BrlA-Dependent Cellular Network Governs Tissue-Specific Secondary Metabolism in the Human Pathogen Aspergillus fumigatus.Morphological changes and induction of antifungal resistance in Aspergillus fumigatus due to different CO2 levels.Fungal Isocyanide Synthases and Xanthocillin Biosynthesis in Aspergillus fumigatus.
P2860
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P2860
Resistance to itraconazole in Aspergillus nidulans and Aspergillus fumigatus is conferred by extra copies of the A. nidulans P-450 14alpha-demethylase gene, pdmA.
description
2001 nî lūn-bûn
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2001 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Resistance to itraconazole in ...... 4alpha-demethylase gene, pdmA.
@ast
Resistance to itraconazole in ...... 4alpha-demethylase gene, pdmA.
@en
type
label
Resistance to itraconazole in ...... 4alpha-demethylase gene, pdmA.
@ast
Resistance to itraconazole in ...... 4alpha-demethylase gene, pdmA.
@en
prefLabel
Resistance to itraconazole in ...... 4alpha-demethylase gene, pdmA.
@ast
Resistance to itraconazole in ...... 4alpha-demethylase gene, pdmA.
@en
P2093
P921
P356
P1476
Resistance to itraconazole in ...... 4alpha-demethylase gene, pdmA.
@en
P2093
P356
10.1093/JAC/48.1.75
P407
P577
2001-07-01T00:00:00Z