about
Single, double and quadruple alanine substitutions at oligomeric interfaces identify hydrophobicity as the key determinant of human neutrophil alpha defensin HNP1 functionTargeted mutations of Bacillus anthracis dihydrofolate reductase condense complex structure−activity relationshipsTargeting the binding interface on a shared receptor subunit of a cytokine family enables the inhibition of multiple member cytokines with selectable target spectrum.Solution Structure of the QUA1 Dimerization Domain of pXqua, the Xenopus Ortholog of QuakingReshaping an enzyme binding pocket for enhanced and inverted stereoselectivity: use of smallest amino acid alphabets in directed evolutionGPCRdb: the G protein-coupled receptor database - an introductionPhage display and peptide mapping of an immunoglobulin light chain fibril-related conformational epitopeA WXW motif is required for the anticancer activity of the TAT-RasGAP317-326 peptideProtein-protein interaction hotspots carved into sequencesAllitridi inhibits multiple cardiac potassium channels expressed in HEK 293 cellsPaFlexPepDock: parallel ab-initio docking of peptides onto their receptors with full flexibility based on RosettaRole of phenylalanine and valine10 residues in the antimicrobial activity and cytotoxicity of piscidin-1The scope of phage display for membrane proteins.In silico saturation mutagenesis and docking screening for the analysis of protein-ligand interaction: the Endothelial Protein C Receptor case study.A dock and coalesce mechanism driven by hydrophobic interactions governs Cdc42 binding with its effector protein ACKIdentification of residues critical for catalysis in a class C beta-lactamase by combinatorial scanning mutagenesis.Phage-display as a tool for quantifying protein stability determinants.A protein interaction surface in nonribosomal peptide synthesis mapped by combinatorial mutagenesis and selection.Phage display of functional, full-length human and viral membrane proteins.Chemical and genetic wrappers for improved phage and RNA display.Identification and characterization of beta-lactamase inhibitor protein-II (BLIP-II) interactions with beta-lactamases using phage display.Molecular and conformational basis of a specific and high-affinity interaction between AlbA and albicidin phytotoxin.Sequence motifs in MADS transcription factors responsible for specificity and diversification of protein-protein interaction.Rosetta FlexPepDock ab-initio: simultaneous folding, docking and refinement of peptides onto their receptors.QnrS1 structure-activity relationships.Molecular inhibition of telomerase recruitment using designer peptides: an in silico approach.Molecular determinants of polyubiquitin linkage selection by an HECT ubiquitin ligase.Highly conserved residues in the helical domain of dengue virus type 1 precursor membrane protein are involved in assembly, precursor membrane (prM) protein cleavage, and entry.N-glycosylation of ICAM-2 is required for ICAM-2-mediated complete suppression of metastatic potential of SK-N-AS neuroblastoma cellsMapping the epitopes of a neutralizing antibody fragment directed against the lethal factor of Bacillus anthracis and cross-reacting with the homologous edema factorRole of key salt bridges in thermostability of G. thermodenitrificans EstGtA2: distinctive patterns within the new bacterial lipolytic enzyme subfamily XIII.2 [corrected]A combinatorial mutagenesis approach for functional epitope mapping on phage-displayed target antigen: application to antibodies against epidermal growth factor.The TLQP-21 peptide activates the G-protein-coupled receptor C3aR1 via a folding-upon-binding mechanismMixture-based combinatorial libraries from small individual peptide libraries: a case study on α1-antitrypsin deficiency.Understanding the molecular basis of EGFR kinase domain/MIG-6 peptide recognition complex using computational analysesSite-directed mutagenesis of HgcA and HgcB reveals amino acid residues important for mercury methylationHigh throughput functional epitope mapping: revisiting phage display platform to scan target antigen surface.Lysine 624 of the amyloid precursor protein (APP) is a critical determinant of amyloid β peptide length: support for a sequential model of γ-secretase intramembrane proteolysis and regulation by the amyloid β precursor protein (APP) juxtamembrane reStructure-based rational design of peptide hydroxamic acid inhibitors to target tumor necrosis factor-α converting enzyme as potential therapeutics for hepatitis.The transmembrane prolines of the mitochondrial ADP/ATP carrier are involved in nucleotide binding and transport and its biogenesis
P2860
Q21132446-EAE4C137-B902-4A02-85E5-D384C13D63EFQ24594645-A34F4369-5945-4DF1-890E-F77A457C66CFQ27312407-3338361B-784E-4440-85DC-EDDBD306EA3AQ27676982-BA6F3903-FE62-424A-B2DC-7AD75F2B144DQ27700225-AFDBF9FE-96FF-443F-87C4-1C57EF737BA1Q28077608-E8AD3E51-0463-47B7-9C1A-38C201472144Q28388530-357DB0D5-0DA8-4F76-AC8B-8CD139F7A10FQ28393795-368737DF-B600-4D33-88CD-B7E31DB5BF50Q28469249-F3BBC6D8-7F34-4BCD-B66D-43DB1544ACCDQ28484383-61C63812-090B-48C9-AC55-2A0FA1B411A9Q28538537-28302D2A-7DEC-4694-9D97-2677E4F2C81DQ28542509-E75F9047-86EA-4460-A9C9-F2759E02AB08Q30155439-0C1DB76A-494E-4436-8E52-CAB649A0B824Q30381635-49115103-4C7A-432B-9D1A-B0EF02CF82BFQ30402373-997E5613-943C-4261-A292-D109B5FA9CC4Q30968138-A2ECD619-777D-4EB4-982F-B2EB36867FA1Q33201959-A654C315-3320-45EB-92B3-4DC05CF40B80Q33237794-21B5AC95-E739-401F-8DFF-0CA1FD61D0E4Q33356309-2CD177B1-1CAA-498A-A723-E72965E6F1FAQ33381323-489C1FB0-F2C1-440E-B637-C069AC38498EQ33544102-2831DE36-3FD4-4043-8408-EF0A7C19BBECQ33716416-3C385590-0EBD-4D00-83B0-35DFEBACD002Q33760996-830AAF32-7288-41BF-B534-B8EC2EC24118Q33900072-E1BA0DA1-E145-4B04-A5BB-88D2B3318648Q33909989-CD2F7331-BE60-4E13-9E8F-3FF94976AD5FQ34437608-DAE74CED-0BAC-4E23-9BCB-A9B39EB3E645Q34547388-62F155DE-DFE5-4FEE-88F5-7DF920C5ED32Q34580259-751BE0E3-EDD2-4F37-8CE0-5FD4E5FD5524Q34743122-1C23CF6F-B58E-48B2-BBF4-10294CCC02C0Q34761514-8D44E234-7F89-4904-BE91-7CF20A9CF4ACQ35014796-A239BC6E-1567-4E3F-8D85-EC63C7BC2A10Q35109650-2A1436D9-F858-4DD2-BA2E-A1D726DED348Q35159111-FA21A3B3-64BA-435F-9DED-5B43B7CE7824Q35170932-D6869E47-F6B5-4804-B23D-0AF344B763FDQ35247477-F5FAF4E9-4BAC-4F88-A7CB-D10EBD41F58DQ35366188-07FD06B6-23E5-43A7-9CE0-1983958C0E7AQ35498790-BD758A99-6F64-442E-9AD2-72597CB551B2Q35562694-6766E6D6-40B8-480C-8AF0-EB4A03207E24Q35659760-0200A521-DC29-4F98-A957-7679E1A43C07Q35879919-40298D40-C7D1-4A17-9C49-08DC87F22ECE
P2860
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Combinatorial alanine-scanning.
@ast
Combinatorial alanine-scanning.
@en
type
label
Combinatorial alanine-scanning.
@ast
Combinatorial alanine-scanning.
@en
prefLabel
Combinatorial alanine-scanning.
@ast
Combinatorial alanine-scanning.
@en
P1476
Combinatorial alanine-scanning.
@en
P2093
P304
P356
10.1016/S1367-5931(00)00206-4
P577
2001-06-01T00:00:00Z