"Mutagenesis" by peptide aptamers identifies genetic network members and pathway connections.
about
The Cbk1p pathway is important for polarized cell growth and cell separation in Saccharomyces cerevisiaeCbk1p, a protein similar to the human myotonic dystrophy kinase, is essential for normal morphogenesis in Saccharomyces cerevisiae.Reversible transdominant inhibition of a metabolic pathway. In vivo evidence of interaction between two sequential tricarboxylic acid cycle enzymes in yeast.Establishment of a chemical synthetic lethality screen in cultured human cellsIn vitro evolution of recognition specificity mediated by SH3 domains reveals target recognition rules.A CDC6 protein-binding peptide selected using a bacterial two-hybrid-like system is a cell cycle inhibitor.Production of cyclic peptides and proteins in vivoOligonucleotide-conjugated beads for transdominant genetic experimentsGenetic selection for modulators of a retinoic-acid-responsive reporter in human cellsIntracellular expression of Peptide fusions for demonstration of protein essentiality in bacteria.Enrichment during transdominant genetic experiments using a flow sorter.Genetic selection for dissociative inhibitors of designated protein-protein interactions.Targeted modification and transportation of cellular proteins.Chemical genetics: ligand-based discovery of gene function.Genetic synthetic lethality screen at the single gene level in cultured human cells.Convergent evolution with combinatorial peptides.Peptide aptamers: recent developments for cancer therapy.An antiproliferative genetic screening identifies a peptide aptamer that targets calcineurin and up-regulates its activity.Identifying small-molecule modulators of protein-protein interactions.Cyclin D3 activates Caspase 2, connecting cell proliferation with cell death.Selective inhibition of TGF-beta responsive genes by Smad-interacting peptide aptamers from FoxH1, Lef1 and CBP.NDR kinases regulate essential cell processes from yeast to humans.Smad4 cooperates with lymphoid enhancer-binding factor 1/T cell-specific factor to increase c-myc expression in the absence of TGF-beta signaling.The eleven-year switch of peptide aptamers.Alterations in the Smad pathway in human cancersAptamers and their potential to selectively target aspects of EGF, Wnt/β-catenin and TGFβ-smad family signaling.Pneumocystis carinii interactions with lung epithelial cells and matrix proteins induce expression and activity of the PcSte20 kinase with subsequent phosphorylation of the downstream cell wall biosynthesis kinase PcCbk1.
P2860
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P2860
"Mutagenesis" by peptide aptamers identifies genetic network members and pathway connections.
description
1999 nî lūn-bûn
@nan
1999 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
"Mutagenesis" by peptide aptam ...... mbers and pathway connections.
@ast
"Mutagenesis" by peptide aptam ...... mbers and pathway connections.
@en
type
label
"Mutagenesis" by peptide aptam ...... mbers and pathway connections.
@ast
"Mutagenesis" by peptide aptam ...... mbers and pathway connections.
@en
prefLabel
"Mutagenesis" by peptide aptam ...... mbers and pathway connections.
@ast
"Mutagenesis" by peptide aptam ...... mbers and pathway connections.
@en
P2093
P2860
P356
P1476
"Mutagenesis" by peptide aptam ...... mbers and pathway connections.
@en
P2093
A Colman-Lerner
P2860
P304
P356
10.1073/PNAS.96.15.8567
P407
P577
1999-07-01T00:00:00Z