%D9%87%DB%8C%D8%AF%D8%B1%D9%88%DA%A9%D8%B3%DB%8C_%D9%85%D8%AA%DB%8C%D9%84%D9%82%D9%84%D9%88%D8%AA%D8%A7%D8%B1%DB%8C%D9%84_%DA%A9%D9%88%D8%A2%D9%86%D8%B2%DB%8C%D9%88%D9%85_%D8%A23-hidroxi-3-metilglutaril-coenzim_AHMG-CoAHMG-CoA%D9%87%DB%8C%D8%AF%D8%B1%D9%88%DA%A9%D8%B3%DB%8C_%D9%85%D8%AA%DB%8C%D9%84%E2%80%8C%DA%AF%D9%84%D9%88%D8%AA%D8%A7%D8%B1%DB%8C%D9%84_%DA%A9%D9%88%D8%A2%D9%86%D8%B2%DB%8C%D9%85_%D8%A23-Hydroxy-3-m%C3%A9thylglutaryl-coenzyme_A3-hidroxi-3-metilglutaril-coencima_A3-idrossi-3-metilglutaril-coenzima_A%E3%83%92%E3%83%89%E3%83%AD%E3%82%AD%E3%82%B7%E3%83%A1%E3%83%81%E3%83%AB%E3%82%B0%E3%83%AB%E3%82%BF%E3%83%AA%E3%83%ABCoA%EB%B2%A0%ED%83%80-%ED%95%98%EC%9D%B4%EB%93%9C%EB%A1%9D%EC%8B%9C_%EB%B2%A0%ED%83%80-%EB%A9%94%ED%8B%B8%EA%B8%80%EB%A3%A8%ED%83%80%EB%A6%B4-CoA3-Hydroksy-3-metyloglutarylokoenzym_AHMG-KoAHMG-KoAQ307532%E7%BE%9F%E7%94%B2%E5%9F%BA%E6%88%8A%E4%BA%8C%E9%85%B8%E5%8D%95%E9%85%B0%E8%BE%85%E9%85%B6A
about
Synthesis and Degradation of Ketone BodiesHMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoAHuman metabolism overviewSynthesis and Degradation of Ketone BodiesReduction of HMG-CoA produces mevalonateacetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASHHMG CoA => acetoacetic acid + acetyl CoAHMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACAbeta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoAMevalonate pathwayFerroptosisCerebral Organic Acidurias, including diseasesCholesterol metabolism (includes both Bloch and Kandutsch-Russell pathways)
P527
Pharmacodynamics and pharmacokinetics of the HMG-CoA reductase inhibitors. Similarities and differences.Inhibition, post-hydroxymethylglutaryl-CoA regulation and relation to cell growth of cholesterol biosynthesis in cultured human skin fibroblasts.Studies on rat hepatic mitochondrial hydroxymethylglutaryl-CoA synthase during the perinatal periodStatins: 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase inhibitors demonstrate anti-atherosclerotic character due to their antioxidant capacity
P921
Q30230825-E0BB483D-AEDF-44CD-A7E7-8F07F455C3A6Q34340158-5C0AA656-D6DF-41F1-84FA-C90E63F8FD34Q44012317-8F5AEA83-8B88-4449-B152-ECBB6112A9DDQ44055637-9FEAE826-148A-4BD4-9B32-809904EA0CEDQ50294067-67C859B2-7F73-43B2-93E3-6672F7BDBE33Q50294343-076E7361-0F9E-4C34-96F4-02B6FE0A7DFBQ50294344-2AEF18D6-A59E-46F6-BAD1-EC6A9949A140Q50294345-88B845A9-9EA8-4FB9-84D3-FA59EB5CC047Q50294977-DCFC18B5-71C9-4D3F-A1C5-AC8C303E1461Q54990302-DD30D33E-D475-4C35-8EB0-90BF6909A9B9Q55446273-E3F1984F-FAC0-42D7-B5CF-94E821B19169Q62060121-4EA6FF84-BC39-4350-B5A4-5326298DFED1Q75741423-972A3B88-6F06-4D82-B571-70F0FC7B6419
P527
description
chemesch Verbindung
@lb
chemical compound
@en
chemical compound
@en-ca
chemical compound
@en-gb
chemická sloučenina
@cs
chemická zlúčenina
@sk
chemiese verbinding
@af
chemische Verbindung
@de
chemische Verbindung
@de-ch
chemische verbinding
@nl
name
(3S)-3-hydroxy-3-methylglutaryl-CoA
@en
3-hidroxi-3-metilglutaril-coencima A
@gl
3-hidroxi-3-metilglutaril-coenzim A
@ca
3-hydroksy-3-metylglutaryl-CoA
@nn
3-hydroxy-3-méthylglutaryl-coenzyme A
@fr
3-idrossi-3-metilglutaril-coenzima A
@it
HMG-CoA
@es
HMG-CoA
@nl
HMG-CoA
@pl
HMG-KoA
@sh
type
label
(3S)-3-hydroxy-3-methylglutaryl-CoA
@en
3-hidroxi-3-metilglutaril-coencima A
@gl
3-hidroxi-3-metilglutaril-coenzim A
@ca
3-hydroksy-3-metylglutaryl-CoA
@nn
3-hydroxy-3-méthylglutaryl-coenzyme A
@fr
3-idrossi-3-metilglutaril-coenzima A
@it
HMG-CoA
@es
HMG-CoA
@nl
HMG-CoA
@pl
HMG-KoA
@sh
altLabel
(S)-3-hydroxy-3-methylglutaryl-coenzyme A
@en
3-Hydroxy-3-methylglutaryl-CoA
@en
3-hidroxi-3-metilglutaril-CoA
@gl
3-hydroksy-3-metylglutaryl-koenzym A
@nn
3-hydroxy-3-methylglutaryl-coenzyme A
@en
3-idrossi-3-metilglutaril-CoA
@it
3-ヒドロキシ-3-メチルグルタリルCoA
@ja
3-羟-3-甲戊二酸单酰辅酶A
@zh
3-羟基-3-甲基戊二酰辅酶A
@zh
3-羟基-3-甲基戊二酸单酰辅酶A
@zh
prefLabel
(3S)-3-hydroxy-3-methylglutaryl-CoA
@en
3-hidroxi-3-metilglutaril-coencima A
@gl
3-hidroxi-3-metilglutaril-coenzim A
@ca
3-hydroksy-3-metylglutaryl-CoA
@nn
3-hydroxy-3-méthylglutaryl-coenzyme A
@fr
3-idrossi-3-metilglutaril-coenzima A
@it
HMG-CoA
@es
HMG-CoA
@nl
HMG-CoA
@pl
HMG-KoA
@sh
P592
P646
P661
P662
P665
P683
P2017
C[C@](CC(=O)O)(CC(=O)SCCNC(=O) ...... C3=C2N=CN=C3N)O)OP(=O)(O)O)O)O
P2063
LMFA07050116
P2064
P2067
911.157468
P231
P232
P233
CC(C)(COP(=O)(O)OP(=O)(O)OCC1C ...... (=O)NCCSC(=O)CC(C)(CC(=O)O)O)O
P234
1S/C27H44N7O20P3S/c1-26(2,21(4 ...... t14-,19-,20-,21+,25-,27+/m1/s1
P235
CABVTRNMFUVUDM-VRHQGPGLSA-N
P2566
100.014.820
P274
C₂₇H₄₄N₇O₂₀P₃S
P3117
DTXSID00935181
P592
CHEMBL1794644