Transcript scanning reveals novel and extensive splice variations in human l-type voltage-gated calcium channel, Cav1.2 alpha1 subunit.
about
X linked cone-rod dystrophy, CORDX3, is caused by a mutation in the CACNA1F geneMolecular mechanism for divergent regulation of Cav1.2 Ca2+ channels by calmodulin and Ca2+-binding protein-1L-type calcium channel targeting and local signalling in cardiac myocytesShould pharmacologists care about alternative splicing? IUPHAR Review 4Calcium Channel Mutations in Cardiac Arrhythmia SyndromesThe cardiac L-type calcium channel distal carboxy terminus autoinhibition is regulated by calcium.Atherosclerosis-related molecular alteration of the human CaV1.2 calcium channel alpha1C subunit.Ca(v)1.2 splice variant with exon 9* is critical for regulation of cerebral artery diameter.Diversity and developmental expression of L-type calcium channel beta2 proteins and their influence on calcium current in murine heart.Calcium Channel CaVα₁ Splice Isoforms - Tissue Specificity and Drug Action.The effect of trichostatin-A and tumor necrosis factor on expression of splice variants of the MaxiK and L-type channels in human myometrium.Smooth muscle-selective alternatively spliced exon generates functional variation in Cav1.2 calcium channels.Vascular smooth muscle phenotypic diversity and functionRegulation of the mutually exclusive exons 8a and 8 in the CaV1.2 calcium channel transcript by polypyrimidine tract-binding protein.CaBP1 regulates voltage-dependent inactivation and activation of Ca(V)1.2 (L-type) calcium channels.Ca(V)1.2 channel N-terminal splice variants modulate functional surface expression in resistance size artery smooth muscle cellsAlternative splicing generates a novel truncated Cav1.2 channel in neonatal rat heart.Functional properties of a newly identified C-terminal splice variant of Cav1.3 L-type Ca2+ channelsAlternative splicing at C terminus of Ca(V)1.4 calcium channel modulates calcium-dependent inactivation, activation potential, and current density.RNA editing of the IQ domain in Ca(v)1.3 channels modulates their Ca²⁺-dependent inactivation.The Brugada syndrome mutation A39V does not affect surface expression of neuronal rat Cav1.2 channels.mRNA transcript diversity creates new opportunities for pharmacological intervention.Functional Characterization of Schizophrenia-Associated Variation in CACNA1C.CACNA1C (Cav1.2) in the pathophysiology of psychiatric diseaseRegulation of maximal open probability is a separable function of Ca(v)beta subunit in L-type Ca2+ channel, dependent on NH2 terminus of alpha1C (Ca(v)1.2alpha).Modulation of distinct isoforms of L-type calcium channels by G(q)-coupled receptors in Xenopus oocytes: antagonistic effects of Gβγ and protein kinase C.A novel Ca(V)1.2 N terminus expressed in smooth muscle cells of resistance size arteries modifies channel regulation by auxiliary subunits.Arrhythmogenesis in Timothy Syndrome is associated with defects in Ca(2+)-dependent inactivationUnderstanding alternative splicing of Cav1.2 calcium channels for a new approach towards individualized medicine.Post-transcriptional modifications and "Calmodulation" of voltage-gated calcium channel function: Reflections by two collaborators of David T YueAlternative splicing: functional diversity among voltage-gated calcium channels and behavioral consequences.Ca(v)1 L-type Ca2+ channel signaling complexes in neurons.Highly variable mRNA expression and splicing of L-type voltage-dependent calcium channel alpha subunit 1C in human heart tissuesA naturally occurring truncated Cav1.2 α1-subunit inhibits Ca2+ current in A7r5 cells.A CaV1.1 Ca2+ channel splice variant with high conductance and voltage-sensitivity alters EC coupling in developing skeletal muscle.Alternative splicing of Cav1.2 channel exons in smooth muscle cells of resistance-size arteries generates currents with unique electrophysiological properties.Aberrant Splicing Promotes Proteasomal Degradation of L-type CaV1.2 Calcium Channels by Competitive Binding for CaVβ Subunits in Cardiac Hypertrophy.Linker flexibility of IVS3-S4 loops modulates voltage-dependent activation of L-type Ca2+ channels.How and why are calcium currents curtailed in the skeletal muscle voltage-gated calcium channels?T-type calcium channels and vascular function: the new kid on the block?
P2860
Q24305973-5842E7D7-C31B-4198-9043-47CBDBD2ABD9Q24306198-5F722EE3-CD62-4745-B404-8565E4C8D0A2Q26853101-8B57FB20-AAC4-44A8-997C-C10C7ED54A88Q27025761-85D5C018-FF99-4A35-8124-273A33CF37A4Q28081380-11C7A22C-599A-4FCF-97CA-8BFDA2C43BEFQ30414950-C130C9A3-447E-432B-8D0D-FD8AF75C6E22Q33261956-F67A3490-E052-4E0D-80CC-3CC4DD86A8D7Q33498339-343FD98E-05A8-45F3-8F13-435CA528B1DEQ33499148-5807EE87-105C-48CA-9812-E13EC5769CA9Q33719513-C095904D-5B27-4E62-9C6C-580F88442AFBQ33901069-2C38271D-535D-4306-831B-A3255DACE82BQ34350275-B6FE73A4-E8DB-42A2-B6A9-1B771FE6700FQ34432730-4F93DF91-2BE1-43D6-8944-5C013DA84484Q34695458-8835BF24-DE18-4310-AA67-45698E3B687CQ34799937-19B2A60A-8164-4924-99CE-721FD8BFBF97Q34868795-C334A2B1-B33D-40F9-9C1D-BE3E6639D47AQ35580904-BBF49B4B-C03C-49E9-A2E4-83CFC3BD4A2FQ35604964-4EB6B21F-8755-4CDB-AC60-B9DE14EC89CAQ35668930-31C8C0A5-8530-4C93-A5EF-F8B3E1A0958CQ35728647-2220905B-0C5E-42F2-B4BD-40E81B279492Q35839314-C38AA997-BE06-4B13-85BD-D46C1B8D4902Q35913120-E151C205-A302-4673-9554-B5FA3EEBDDF0Q36045144-04447C4F-92BE-40A8-8650-5218B195BC48Q36281961-101E4F6D-2405-417A-B90B-B68554896021Q36295788-A7C04C86-4D17-4CB1-B127-7C09D4E0F2ECQ36507732-EADAA904-2926-42B0-9254-45DA02814360Q36512670-0D070F80-5632-463E-8C97-B1F052F41F4DQ36540252-65E974A8-0BE9-400E-947D-6AB8E828F1E0Q36681427-A3840F88-6E51-4224-BD9D-612AEAA233B0Q36714856-85E92B51-FBBC-438E-98D4-49CDD89D9A55Q36763193-9D6C614E-1F6C-4AEF-844F-B56E684204B9Q37081747-B818EF6C-7E82-499D-884F-60FE3326E194Q37208437-6E52C264-4739-4219-B459-5451A8464671Q37234587-4EB5C83A-2EC4-4E3B-80F2-91ACF78922D9Q37260318-27625EBD-4DF3-4449-8B1C-17A1F527E66EQ37298267-569990C4-C663-451F-A49C-237F304F8B3AQ37330436-B05EE78F-56B2-43F9-8BDD-D0CDCD04728BQ37613802-73629EA3-FFE8-41B6-ADF0-19A5F4F6EDEDQ37672288-9B401924-C265-42F1-BE21-4DE507314EC1Q37822589-2C721E75-3F5B-43C4-B52D-2620AAD2494C
P2860
Transcript scanning reveals novel and extensive splice variations in human l-type voltage-gated calcium channel, Cav1.2 alpha1 subunit.
description
2004 nî lūn-bûn
@nan
2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Transcript scanning reveals no ...... hannel, Cav1.2 alpha1 subunit.
@ast
Transcript scanning reveals no ...... hannel, Cav1.2 alpha1 subunit.
@en
type
label
Transcript scanning reveals no ...... hannel, Cav1.2 alpha1 subunit.
@ast
Transcript scanning reveals no ...... hannel, Cav1.2 alpha1 subunit.
@en
prefLabel
Transcript scanning reveals no ...... hannel, Cav1.2 alpha1 subunit.
@ast
Transcript scanning reveals no ...... hannel, Cav1.2 alpha1 subunit.
@en
P2093
P2860
P356
P1476
Transcript scanning reveals no ...... channel, Cav1.2 alpha1 subunit
@en
P2093
Chye Yun Yu
David T Yue
Songqing Lu
Tuck Wah Soong
Zhen Zhi Tang
P2860
P304
44335-44343
P356
10.1074/JBC.M407023200
P407
P577
2004-08-06T00:00:00Z