Misassembly of full-length Disrupted-in-Schizophrenia 1 protein is linked to altered dopamine homeostasis and behavioral deficits.
about
Drug Abuse and Psychosis: New Insights into Drug-induced PsychosisSimultaneous effects on parvalbumin-positive interneuron and dopaminergic system development in a transgenic rat model for sporadic schizophrenia.The impact of Disrupted-in-Schizophrenia 1 (DISC1) on the dopaminergic system: a systematic review.Aggregation of scaffolding protein DISC1 dysregulates phosphodiesterase 4 in Huntington's diseaseAn unpredicted aggregation-critical region of the actin-polymerizing protein TRIOBP-1/Tara, determined by elucidation of its domain structure.Transfer of disrupted-in-schizophrenia 1 aggregates between neuronal-like cells occurs in tunnelling nanotubes and is promoted by dopamine.Potential synergistic action of 19 schizophrenia risk genes in the thalamus.Role of DISC1 in Neuronal Trafficking and its Implication in Neuropsychiatric Manifestation and Neurotherapeutics.ErbB4 signaling in dopaminergic axonal projections increases extracellular dopamine levels and regulates spatial/working memory behaviors.A Mutation in NPAS3 That Segregates with Schizophrenia in a Small Family Leads to Protein Aggregation.Abnormal wake/sleep pattern in a novel gain-of-function model of DISC1Biophysical insights from a single chain camelid antibody directed against the Disrupted-in-Schizophrenia 1 protein.Adolescent stress leads to glutamatergic disturbance through dopaminergic abnormalities in the prefrontal cortex of genetically vulnerable mice.A structural organization for the Disrupted in Schizophrenia 1 protein, identified by high-throughput screening, reveals distinctly folded regions, which are bisected by mental illness-related mutations.FBXW7 regulates DISC1 stability via the ubiquitin-proteosome system.Quantitative Proteomics of Synaptosomal Fractions in a Rat Overexpressing Human DISC1 Gene Indicates Profound Synaptic Dysregulation in the Dorsal Striatum.Metabolic profile associated with distinct behavioral coping strategies of 129Sv and Bl6 mice in repeated motility test.DISC1 is a coordinator of intracellular trafficking to shape neuronal development and connectivity.Repeated Administration of D-Amphetamine Induces Distinct Alterations in Behavior and Metabolite Levels in 129Sv and Bl6 Mouse Strains.
P2860
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P2860
Misassembly of full-length Disrupted-in-Schizophrenia 1 protein is linked to altered dopamine homeostasis and behavioral deficits.
description
2016 nî lūn-bûn
@nan
2016 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Misassembly of full-length Dis ...... tasis and behavioral deficits.
@ast
Misassembly of full-length Dis ...... tasis and behavioral deficits.
@en
type
label
Misassembly of full-length Dis ...... tasis and behavioral deficits.
@ast
Misassembly of full-length Dis ...... tasis and behavioral deficits.
@en
prefLabel
Misassembly of full-length Dis ...... tasis and behavioral deficits.
@ast
Misassembly of full-length Dis ...... tasis and behavioral deficits.
@en
P2093
P2860
P50
P356
P1433
P1476
Misassembly of full-length Dis ...... stasis and behavioral deficits
@en
P2093
A Müller-Schiffmann
C Chwiesko
G Poschmann
I Prikulis
J P Huston
P2860
P2888
P304
P356
10.1038/MP.2015.194
P407
P577
2016-01-12T00:00:00Z