Selection of phage-displayed fab antibodies on the active conformation of ras yields a high affinity conformation-specific antibody preventing the binding of c-Raf kinase to Ras.
about
Two-state selection of conformation-specific antibodiesPhage display and pharmacogenomics.Ras/Raf signalling and emerging pharmacotherapeutic targets.Generation of a single chain antibody variable fragment (scFv) to sense selectively RhoB activation.Anti-(Raf-1) RNA aptamers that inhibit Ras-induced Raf-1 activation.Point mutants of c-raf-1 RBD with elevated binding to v-Ha-Ras.Identification of a GTP-bound Rho specific scFv molecular sensor by phage display selection.
P2860
Q33408112-82B4CB46-7F88-4C8F-8186-8D087C924FE7Q34188535-C3CBB0A5-263B-412A-8053-7324D99AE35DQ34660771-D7D38AAC-66FE-4D23-A9A7-51EA6DE862CFQ35388015-B0958C90-C9E4-444F-BA7F-759DD25CFEBBQ40749465-55C2866B-DD55-4D0B-B7D2-26EE1DA88D27Q42799900-16712B23-AB12-43A5-82A2-B5F027062342Q43151828-6CF337D0-EDC6-403C-B357-9A255AE1D782
P2860
Selection of phage-displayed fab antibodies on the active conformation of ras yields a high affinity conformation-specific antibody preventing the binding of c-Raf kinase to Ras.
description
1999 nî lūn-bûn
@nan
1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Selection of phage-displayed f ...... inding of c-Raf kinase to Ras.
@ast
Selection of phage-displayed f ...... inding of c-Raf kinase to Ras.
@en
type
label
Selection of phage-displayed f ...... inding of c-Raf kinase to Ras.
@ast
Selection of phage-displayed f ...... inding of c-Raf kinase to Ras.
@en
prefLabel
Selection of phage-displayed f ...... inding of c-Raf kinase to Ras.
@ast
Selection of phage-displayed f ...... inding of c-Raf kinase to Ras.
@en
P2093
P2860
P1433
P1476
Selection of phage-displayed f ...... binding of c-Raf kinase to Ras
@en
P2093
A P de Bruïne
A Wittinghofer
H R Hoogenboom
P2860
P304
P356
10.1016/S0014-5793(99)01617-8
P407
P50
P577
1999-12-01T00:00:00Z