Persistence of p53 mutations and resistance of keratinocytes to apoptosis are associated with the increased susceptibility of mice lacking the XPC gene to UV carcinogenesis.
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Differential role of transcription-coupled repair in UVB-induced G2 arrest and apoptosis in mouse epidermisError-prone translesion replication of damaged DNA suppresses skin carcinogenesis by controlling inflammatory hyperplasiaThe DNA damage-binding protein XPC is a frequent target for inactivation in squamous cell carcinomasXPC silencing in normal human keratinocytes triggers metabolic alterations that drive the formation of squamous cell carcinomas.p53 suppression overwhelms DNA polymerase eta deficiency in determining the cellular UV DNA damage responseReduced XPC DNA repair gene mRNA levels in clinically normal parents of xeroderma pigmentosum patients.Catalase overexpression reduces UVB-induced apoptosis in a human xeroderma pigmentosum reconstructed epidermis.
P2860
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P2860
Persistence of p53 mutations and resistance of keratinocytes to apoptosis are associated with the increased susceptibility of mice lacking the XPC gene to UV carcinogenesis.
description
1999 nî lūn-bûn
@nan
1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Persistence of p53 mutations a ...... XPC gene to UV carcinogenesis.
@ast
Persistence of p53 mutations a ...... XPC gene to UV carcinogenesis.
@en
type
label
Persistence of p53 mutations a ...... XPC gene to UV carcinogenesis.
@ast
Persistence of p53 mutations a ...... XPC gene to UV carcinogenesis.
@en
prefLabel
Persistence of p53 mutations a ...... XPC gene to UV carcinogenesis.
@ast
Persistence of p53 mutations a ...... XPC gene to UV carcinogenesis.
@en
P2093
P2860
P356
P1433
P1476
Persistence of p53 mutations a ...... XPC gene to UV carcinogenesis.
@en
P2093
Ananthaswamy HN
Khaskina P
P2860
P2888
P304
P356
10.1038/SJ.ONC.1203147
P407
P577
1999-12-01T00:00:00Z
P5875
P6179
1050596806