Prediction of organic anion-transporting polypeptide 1B1- and 1B3-mediated hepatic uptake of statins based on transporter protein expression and activity data.
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Investigating Transporter-Mediated Drug-Drug Interactions Using a Physiologically Based Pharmacokinetic Model of Rosuvastatin.Abundance of Hepatic Transporters in Caucasians: A Meta-Analysis.More Power to OATP1B1: An Evaluation of Sample Size in Pharmacogenetic Studies Using a Rosuvastatin PBPK Model for Intestinal, Hepatic, and Renal Transporter-Mediated Clearances.Hepatic drug transporters: the journey so far.The regulation of human hepatic drug transporter expression by activation of xenobiotic-sensing nuclear receptors.Assessment of drug metabolism enzyme and transporter pharmacogenetics in drug discovery and early development: perspectives of the I-PWG.Epigenetic regulation of drug transporter expression in human tissues.The role of organic anion transporting polypeptides in drug absorption, distribution, excretion and drug-drug interactions.Clinical Pharmacokinetics of Sacubitril/Valsartan (LCZ696): A Novel Angiotensin Receptor-Neprilysin Inhibitor.Mixed effects of OATP1B1, BCRP and NTCP polymorphisms on the population pharmacokinetics of pravastatin in healthy volunteers.PBPK modeling of irbesartan: incorporation of hepatic uptake.Application of the extended clearance concept classification system (ECCCS) to predict the victim drug-drug interaction potential of statins.Association of genetic variations with pharmacokinetics and lipid-lowering response to atorvastatin in healthy Korean subjectsA physiologically based pharmacokinetic (PBPK) parent-metabolite model of the chemotherapeutic zoptarelin doxorubicin-integration of in vitro results, Phase I and Phase II data and model application for drug-drug interaction potential analysis.In vitro studies with two human organic anion transporters: OAT2 and OAT7.Erratum to: Clinical Pharmacokinetics of Sacubitril/Valsartan (LCZ696): A Novel Angiotensin Receptor-Neprilysin Inhibitor.Epigallocatechin-3-gallate decreases the transport and metabolism of simvastatin in rats.The influences of SLCO1B1 and ABCB1 genotypes on the pharmacokinetics of simvastatin, in relation to CYP3A4 inhibition.Role of Hepatic Drug Transporters in Drug Development.In vitro and clinical evaluation of OATP-mediated drug interaction potential of sacubitril/valsartan (LCZ696).Mechanistic Modeling of Pitavastatin Disposition in Sandwich-Cultured Human Hepatocytes: A Proteomics-Informed Bottom-Up Approach.The influence of the intestinal microflora to the efficacy of Rosuvastatin.Ginsenoside Rb1 and Rd Remarkably Inhibited the Hepatic Uptake of Ophiopogonin D in Shenmai Injection Mediated by OATPs/oatps
P2860
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P2860
Prediction of organic anion-transporting polypeptide 1B1- and 1B3-mediated hepatic uptake of statins based on transporter protein expression and activity data.
description
2014 nî lūn-bûn
@nan
2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Prediction of organic anion-tr ...... expression and activity data.
@ast
Prediction of organic anion-tr ...... expression and activity data.
@en
type
label
Prediction of organic anion-tr ...... expression and activity data.
@ast
Prediction of organic anion-tr ...... expression and activity data.
@en
prefLabel
Prediction of organic anion-tr ...... expression and activity data.
@ast
Prediction of organic anion-tr ...... expression and activity data.
@en
P2093
P356
P1476
Prediction of organic anion-tr ...... expression and activity data.
@en
P2093
Annett Kunze
Birk Poller
Gian Camenisch
P304
P356
10.1124/DMD.114.058412
P50
P577
2014-07-02T00:00:00Z