Establishment of a binding assay for protein kinase C isozymes using synthetic C1 peptides and development of new medicinal leads with protein kinase C isozyme and C1 domain selectivity.
about
Identification of the activator-binding residues in the second cysteine-rich regulatory domain of protein kinase Cθ (PKCθ)Targeting of protein kinase C-epsilon during Fcgamma receptor-dependent phagocytosis requires the epsilonC1B domain and phospholipase C-gamma1.PKC-ε pseudosubstrate and catalytic activity are necessary for membrane delivery during IgG-mediated phagocytosis.Diacylglycerol-dependent binding recruits PKCtheta and RasGRP1 C1 domains to specific subcellular localizations in living T lymphocytes.Two new lyngbyatoxin derivatives from the Cyanobacterium, Moorea producens.Structural Basis for the Failure of the C1 Domain of Ras Guanine Nucleotide Releasing Protein 2 (RasGRP2) to Bind Phorbol Ester with High Affinity.Potential for pharmacological manipulation of human embryonic stem cells.The many hats of protein kinase Cδ: one enzyme with many functions.A comparison of the membrane binding properties of C1B domains of PKCgamma, PKCdelta, and PKCepsilon.A novel diacylglycerol-lactone shows marked selectivity in vitro among C1 domains of protein kinase C (PKC) isoforms alpha and delta as well as selectivity for RasGRP compared with PKCalpha.Alcohol binding in the C1 (C1A+C1B) domain of protein kinase C epsilon.Interfacial partitioning of a loop hinge residue contributes to diacylglycerol affinity of conserved region 1 domains.Modeling studies on the structural determinants for the DAG/phorbol ester binding to C1 domain.The C1 domain of Vav3, a novel potential therapeutic target.REDOR NMR Reveals Multiple Conformers for a Protein Kinase C Ligand in a Membrane Environment.Mutant protein kinase Cgamma found in spinocerebellar ataxia type 14 is susceptible to aggregation and causes cell death.Ethanol-Induced Changes in PKCε: From Cell to Behavior.
P2860
Q27683701-1882EE7D-5C4B-4F08-B827-0762BCC3B5C5Q30476704-29235072-0808-499B-BA00-78CF224FBBB1Q30540719-A4C2DA75-47E1-47EB-97C6-88FDAE1AAFCAQ34360144-11994ABA-B4FD-40C8-BC3F-81D7F84F35A6Q34780449-B9444895-C9C4-4118-B037-B7F5EB30E425Q36987649-2E361B98-51E2-4517-BF21-6CD931563F03Q38003694-FA7D4CEA-4EA1-4995-B969-97B66E991132Q38268437-924E5288-65AD-45B0-A7C0-753F66779AF2Q39857220-89A6C851-8512-4A90-BFC6-C5B29BB4E7E7Q40415755-C0E96A26-5F11-447A-AAD6-15AAE77C71EBQ40696736-A465F057-BA63-4EDB-9783-684AFEC16CB9Q42206669-193C92C7-3BD2-4EB2-BDB0-099FC796B201Q46231206-052EA445-77ED-43D2-85EF-A940D9F8EB06Q47777161-3344D8E4-D775-4F66-9AEA-E8C6A92488F3Q49384958-F9D46B68-985B-4EB0-A549-CF54D95E3F65Q50764411-4932D669-05BF-49E7-90DC-ED77F99CBF9CQ54980051-EDE40AA1-2684-4EC2-AEE5-4C684FB1D8D2
P2860
Establishment of a binding assay for protein kinase C isozymes using synthetic C1 peptides and development of new medicinal leads with protein kinase C isozyme and C1 domain selectivity.
description
2002 nî lūn-bûn
@nan
2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Establishment of a binding ass ...... yme and C1 domain selectivity.
@ast
Establishment of a binding ass ...... yme and C1 domain selectivity.
@en
type
label
Establishment of a binding ass ...... yme and C1 domain selectivity.
@ast
Establishment of a binding ass ...... yme and C1 domain selectivity.
@en
prefLabel
Establishment of a binding ass ...... yme and C1 domain selectivity.
@ast
Establishment of a binding ass ...... yme and C1 domain selectivity.
@en
P2093
P1476
Establishment of a binding ass ...... yme and C1 domain selectivity.
@en
P2093
Akifumi Nakahara
Hajime Ohigashi
Hiroaki Konishi
Hiroyuki Fukuda
Kaori Kashiwagi
Mayumi Shindo
Naoaki Saito
Ushio Kikkawa
Yu Nakagawa
P304
P356
10.1016/S0163-7258(02)00196-1
P577
2002-02-01T00:00:00Z