Asymptomatic human CD4+ cytotoxic T-cell epitopes identified from herpes simplex virus glycoprotein B - Wikidata - wikimedia - TriplyDB

Asymptomatic human CD4+ cytotoxic T-cell epitopes identified from herpes simplex virus glycoprotein B

Asymptomatic human CD4+ cytotoxic T-cell epitopes identified from herpes simplex virus glycoprotein B

http://www.wikidata.org/entity/Q30847945

about

Towards a rational design of an asymptomatic clinical herpes vaccine: the old, the new, and the unknown Asymptomatic HLA-A*02:01-restricted epitopes from herpes simplex virus glycoprotein B preferentially recall polyfunctional CD8+ T cells from seropositive asymptomatic individuals and protect HLA transgenic mice against ocular herpes.Specificities of human CD4+ T cell responses to an inactivated flavivirus vaccine and infection: correlation with structure and epitope prediction Current status and prospects for development of an HSV vaccine A single intramuscular vaccination of mice with the HSV-1 VC2 virus with mutations in the glycoprotein K and the membrane protein UL20 confers full protection against lethal intravaginal challenge with virulent HSV-1 and HSV-2 strains.Engagement of TLR2 reverses the suppressor function of conjunctiva CD4+CD25+ regulatory T cells and promotes herpes simplex virus epitope-specific CD4+CD25- effector T cell responses.HLA-A02:01-restricted epitopes identified from the herpes simplex virus tegument protein VP11/12 preferentially recall polyfunctional effector memory CD8+ T cells from seropositive asymptomatic individuals and protect humanized HLA-A*02:01 transgeni Of mice and not humans: how reliable are animal models for evaluation of herpes CD8(+)-T cell-epitopes-based immunotherapeutic vaccine candidates?Phenotypic and functional characterization of herpes simplex virus glycoprotein B epitope-specific effector and memory CD8+ T cells from symptomatic and asymptomatic individuals with ocular herpes Therapeutic immunization with a mixture of herpes simplex virus 1 glycoprotein D-derived “asymptomatic” human CD8+ T-cell epitopes decreases spontaneous ocular shedding in latently infected HLA transgenic rabbits: association with low frequency of l A Herpes Simplex Virus Type 1 Human Asymptomatic CD8+ T-Cell Epitopes-Based Vaccine Protects Against Ocular Herpes in a "Humanized" HLA Transgenic Rabbit Model.Immunodominant "asymptomatic" herpes simplex virus 1 and 2 protein antigens identified by probing whole-ORFome microarrays with serum antibodies from seropositive asymptomatic versus symptomatic individuals Discovery of potential diagnostic and vaccine antigens in herpes simplex virus 1 and 2 by proteome-wide antibody profiling.A genital tract peptide epitope vaccine targeting TLR-2 efficiently induces local and systemic CD8+ T cells and protects against herpes simplex virus type 2 challenge Developing an asymptomatic mucosal herpes vaccine: the present and the future.Future of an "Asymptomatic" T-cell Epitope-Based Therapeutic Herpes Simplex Vaccine A lentiviral vector-based, herpes simplex virus 1 (HSV-1) glycoprotein B vaccine affords cross-protection against HSV-1 and HSV-2 genital infections.Peripheral blood CD4 T-cell and plasmacytoid dendritic cell (pDC) reactivity to herpes simplex virus 2 and pDC number do not correlate with the clinical or virologic severity of recurrent genital herpes.Targeting the genital tract mucosa with a lipopeptide/recombinant adenovirus prime/boost vaccine induces potent and long-lasting CD8+ T cell immunity against herpes: importance of MyD88.Mucosal herpes immunity and immunopathology to ocular and genital herpes simplex virus infections.Current trends in negative immuno-synergy between two sexually transmitted infectious viruses: HIV-1 and HSV-1/2.The Herpes Simplex Virus Latency-Associated Transcript Gene Is Associated with a Broader Repertoire of Virus-Specific Exhausted CD8+ T Cells Retained within the Trigeminal Ganglia of Latently Infected HLA Transgenic Rabbits Asymptomatic memory CD8+ T cells: from development and regulation to consideration for human vaccines and immunotherapeutics A novel HLA (HLA-A*0201) transgenic rabbit model for preclinical evaluation of human CD8+ T cell epitope-based vaccines against ocular herpes.Single dose of glycoprotein K (gK)-deleted HSV-1 live-attenuated virus protects mice against lethal vaginal challenge with HSV-1 and HSV-2 and induces lasting T cell memory immune responses New concepts in herpes simplex virus vaccine development: notes from the battlefield.Human Asymptomatic Epitopes Identified from the Herpes Simplex Virus Tegument Protein VP13/14 (UL47) Preferentially Recall Polyfunctional Effector Memory CD44high CD62Llow CD8+ TEM Cells and Protect Humanized HLA-A*02:01 Transgenic Mice against Ocul HSV-2 vaccine: current status and insight into factors for developing an efficient vaccine.Prior Corneal Scarification and Injection of Immune Serum are Not Required Before Ocular HSV-1 Infection for UV-B-Induced Virus Reactivation and Recurrent Herpetic Corneal Disease in Latently Infected Mice.Immunology in the Clinic Review Series; focus on host responses: T cell responses to herpes simplex viruses.Immune response of T cells during herpes simplex virus type 1 (HSV-1) infection.Bolstering the Number and Function of HSV-1-Specific CD8+ Effector Memory T Cells and Tissue-Resident Memory T Cells in Latently Infected Trigeminal Ganglia Reduces Recurrent Ocular Herpes Infection and Disease.CXCL10/CXCR3-Dependent Mobilization of Herpes Simplex Virus-Specific CD8+ TEM and CD8+ TRM Cells within Infected Tissues Allows Efficient Protection against Recurrent Herpesvirus Infection and Disease.Asian elephant T cell responses to Elephant Endotheliotropic Herpesvirus (EEHV).Human Asymptomatic Epitope Peptide/CXCL10-Based Prime/Pull Vaccine Induces Herpes Simplex Virus-Specific Gamma Interferon-Positive CD107 CD8 T Cells That Infiltrate the Corneas and Trigeminal Ganglia of Humanized HLA Transgenic Rabbits and Protect ag

P2860

Q21296712-6E6A20ED-1651-44F1-BB61-B9256D5764EE Q33755236-35B26F51-804F-41DC-92A6-015D39A95AF4 Q33900413-7560CF62-7513-4586-B30D-3210CA80ABA9 Q33931016-AECF345F-5E6A-4D42-AAB2-7D59876CA6DC Q34414463-78DDEB8F-854E-4868-9E8F-F4A63E26EE2A Q35027578-3E9B1A42-E2D0-48F1-8228-0D9820821742 Q35122383-6129EE18-7105-4D7E-9928-99C331ABB281 Q35173777-B12A4077-285A-42A6-9322-D789B2662AD2 Q35487893-AB4B5B17-63B2-448E-B303-7B6FCA22F8F2 Q35745358-7916D7A6-467D-4687-91FE-5DB425EEAB96 Q35769258-B67FDD21-E15B-461F-808E-F08D9DB16DFC Q35868029-F2C5929E-6FEF-463E-924B-E83621EC6F67 Q35868054-A6616D71-8750-4CB4-9215-1244CE267CFE Q35871689-6EEC150C-26A9-4C02-BEAB-BFDA0ECDBDF1 Q35881975-E5E824CF-CB25-474B-BB6A-4A59E204A3B6 Q36025675-B665D7A4-A412-446C-80E5-943E1AFC3FEE Q36086635-0AF602AE-C4A8-449D-B3E8-EC8F5B60D6CC Q36246306-52424F24-B236-49BD-86CA-8C2B9FD5F393 Q36339059-1F5BDD6C-664F-4F6C-9038-A8FE822498C9 Q36520832-0DB3ADF5-F471-4EDF-9A0E-B8B9F0C8146F Q36555158-53BDDA38-65A2-4371-814B-A5F6E0B90BB6 Q36736366-20CBEC87-937F-4AEB-A6CA-B9946116ADCE Q36977847-38F4E880-13FE-44A9-9994-EE2FBE2EC48E Q37118262-B907A5ED-211B-4C95-BCD1-627BD1FD446D Q37305004-74C118F0-E884-441A-9F90-6C9953BAED25 Q37384857-C4AF7042-3C6D-43B6-8C61-ACF8B2D818E5 Q37560770-0714C896-0949-4581-A609-686A3BDDFCEA Q37611796-DA34F8CF-0680-47EE-ABB5-A2B026082C8F Q37699104-11046338-BDE9-45CE-9667-26DF28EE394D Q37963480-640ADCBC-2427-42FE-BDAF-95A39CA7D395 Q39221171-9CBE3270-5AF8-47FF-B4A3-E95FA851E011 Q40187650-4C079B75-D1A3-48C3-9475-45556DBCE21C Q40216595-71755E30-E098-4F47-8381-1FBF5CFC7A24 Q47269094-36CACC96-2A9C-482F-86D5-CDB86EBF1B29 Q57753552-215F33BC-2762-456F-8D07-E7D2B79AF0E5

P2860

Asymptomatic human CD4+ cytotoxic T-cell epitopes identified from herpes simplex virus glycoprotein B

http://www.wikidata.org/entity/Q30847945

description

2008 nî lūn-bûn

@nan

2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

Asymptomatic human CD4+ cytoto ...... s simplex virus glycoprotein B

@ast

Asymptomatic human CD4+ cytoto ...... s simplex virus glycoprotein B

@en

type

label

Asymptomatic human CD4+ cytoto ...... s simplex virus glycoprotein B

@ast

Asymptomatic human CD4+ cytoto ...... s simplex virus glycoprotein B

@en

prefLabel

Asymptomatic human CD4+ cytoto ...... s simplex virus glycoprotein B

@ast

Asymptomatic human CD4+ cytoto ...... s simplex virus glycoprotein B

@en

P1433

Q30847945-9D08A7C9-3FCB-42D5-B0C6-61A076A7A573

P1476

Q30847945-0F5AC1F5-28FB-4C76-936A-C43DBDE0D129

P2093

Q30847945-3936E7F4-1328-40E5-B123-389C88A9D7DF

Q30847945-5900AC0E-1537-485B-95A1-EEC9A2F5374A

Q30847945-5DA52D86-4DB9-4B93-BF97-278B4B8E2CEE

Q30847945-6EA90ADB-7019-4DFD-8F5D-BDC60EC0BC2D

Q30847945-78145B08-D274-479D-9AA2-B88555877EA7

Q30847945-7DE043D2-CABB-473C-B8F6-6563287388CB

Q30847945-91C59830-9B09-4574-BA7D-FB0E1A5E8D4A

Q30847945-E6650456-162A-44EA-BA0C-36CD2FCA4FEE

P2860

Q30847945-0324C5BA-897F-4C92-A45D-E7F1C4B26114

Q30847945-0C211AA9-BFD8-487F-9B5E-6CADAC62F700

Q30847945-0CC12206-6932-4E51-A357-9ED3082ABF7D

Q30847945-0D4E7C88-F946-4D73-A143-90200A9E3821

Q30847945-16523BB0-B5E1-40AE-800C-017A26DF0B5A

Q30847945-18334E75-A137-4B80-86E1-C03FCCFC0F12

Q30847945-1E6337BC-2AB8-4914-8258-33A112357839

Q30847945-1EB77B7A-CF8B-4AC3-A54F-E538656978A2

Q30847945-1FE49024-02BC-496C-8233-AACA3F806AA8

Q30847945-21F656FC-2C0C-42A5-810B-1D728AD26EE4

P304

Q30847945-93836F24-729B-4370-A179-E6AEF7BB630A

P31

Q30847945-9365120F-8D35-4170-8525-CC145A61B2C4

P356

Q30847945-76C2C44A-995B-487B-8915-8A0A545C9559

P433

Q30847945-1CE1BEA3-20A7-47BE-87AD-E4475A658DC3

P478

Q30847945-3A605683-5A10-4DFA-9D48-E991C4812902

P577

Q30847945-05170579-33D8-4A7D-9980-548C143DAC52

P698

Q30847945-3A8D6F2B-FE30-443E-B170-276CA732ADBC

P921

Q30847945-7DA6CC80-D7B0-4C3C-9015-7B85E1E90585

P932

Q30847945-911F639B-E489-4932-8E10-23889C97EE08

P356

P1433

Journal of Virology

P1476

Asymptomatic human CD4+ cytoto ...... s simplex virus glycoprotein B

@en

P2093

Alex Nguyen

http://www.w3.org/2001/XMLSchema#string

Aziz Alami Chentoufi

http://www.w3.org/2001/XMLSchema#string

Bernard Maillère

http://www.w3.org/2001/XMLSchema#string

Guillaume Durand

http://www.w3.org/2001/XMLSchema#string

Ilham Bettahi

http://www.w3.org/2001/XMLSchema#string

Lbachir BenMohamed

http://www.w3.org/2001/XMLSchema#string

Nicholas R Binder

http://www.w3.org/2001/XMLSchema#string

Noureddine Berka

http://www.w3.org/2001/XMLSchema#string

P2860

Herpes Simplex: Insights on Pathogenesis and Possible Vaccines

HSV-1 DNA in tears and saliva of normal adults

HLA antigens associated with susceptibility to herpes simplex virus infection

Herpes simplex virus epidemiology and ocular importance.

Herpes simplex virus type 2 vaccines: new ground for optimism?

Nine major HLA class I supertypes account for the vast preponderance of HLA-A and -B polymorphism.

Asymptomatic reactivation of herpes simplex virus in women after the first episode of genital herpes.

Viral encephalitis: familiar infections and emerging pathogens.

Limits in reliability of glycoprotein G-based type-specific serologic assays for herpes simplex virus types 1 and 2.

The human immunodeficiency virus: infectivity and mechanisms of pathogenesis.

P304

11792-11802

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1128/JVI.00692-08

http://www.w3.org/2001/XMLSchema#string

P433

23

http://www.w3.org/2001/XMLSchema#string

P478

82

http://www.w3.org/2001/XMLSchema#string

P577

2008-09-17T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

18799581

http://www.w3.org/2001/XMLSchema#string

P921

P932

2583686

http://www.w3.org/2001/XMLSchema#string