Alanine-scanning mutagenesis of Aspergillus gamma-tubulin yields diverse and novel phenotypes
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The functions of myosin II and myosin V homologs in tip growth and septation in Aspergillus nidulansgamma-tubulin plays an essential role in the coordination of mitotic events.The role of microtubules in rapid hyphal tip growth of Aspergillus nidulans.Molecular and structural characterization of the spindle pole bodies in the fission yeast Schizosaccharomyces japonicus var japonicus.NME7 is a functional component of the γ-tubulin ring complexEffects of {gamma}-tubulin complex proteins on microtubule nucleation and catastrophe in fission yeast.Cytoplasmic dynein's mitotic spindle pole localization requires a functional anaphase-promoting complex, gamma-tubulin, and NUDF/LIS1 in Aspergillus nidulans.Gamma-tubulin and the C-terminal motor domain kinesin-like protein, KLPA, function in the establishment of spindle bipolarity in Aspergillus nidulans.Gamma-tubulin regulates the anaphase-promoting complex/cyclosome during interphase.The Drosophila gamma-tubulin small complex subunit Dgrip84 is required for structural and functional integrity of the spindle apparatus.Mutational analyses reveal a novel function of the nucleotide-binding domain of gamma-tubulin in the regulation of basal body biogenesis.Spatial regulation of the spindle assembly checkpoint and anaphase-promoting complex in Aspergillus nidulansThe Polo-like kinase PLKA in Aspergillus nidulans is not essential but plays important roles during vegetative growth and development.γ-Tubulin plays a key role in inactivating APC/C(Cdh1) at the G(1)-S boundaryTetrahymena thermophila contains a conventional gamma-tubulin that is differentially required for the maintenance of different microtubule-organizing centers.Distinct Dgrip84 isoforms correlate with distinct gamma-tubulins in Drosophila.Dual-Color imaging of nuclear division and mitotic spindle elongation in live cells of Aspergillus nidulans.Screening for microtubule-disrupting antifungal agents by using a mitotic-arrest mutant of Aspergillus nidulans and novel action of phenylalanine derivatives accompanying tubulin loss.The γ-tubulin-specific inhibitor gatastatin reveals temporal requirements of microtubule nucleation during the cell cycle.GTP regulates the microtubule nucleation activity of γ-tubulin.Overexpression of truncated gamma-tubulins disrupts mitotic aster formation in Xenopus oocyte extractsFunctional dissection of the gamma-tubulin complex by suppressor analysis of gtb1 and alp4 mutations in Schizosaccharomyces pombe.Different roles of two gamma-tubulin isotypes in the cytoskeleton of the Antarctic ciliate Euplotes focardii: remodelling of interaction surfaces may enhance microtubule nucleation at low temperature.In vivo analysis of the functions of gamma-tubulin-complex proteins.The GCP3-interacting proteins GIP1 and GIP2 are required for γ-tubulin complex protein localization, spindle integrity, and chromosomal stability.Regulation of hyphal morphogenesis by cdc42 and rac1 homologues in Aspergillus nidulans.Plant gamma-tubulin interacts with alphabeta-tubulin dimers and forms membrane-associated complexes.Role of microtubules in tip growth of fungi.Gamma-tubulin is essential for microtubule organization and development in Arabidopsis.Multi-sited mutations of beta-tubulin are involved in benzimidazole resistance and thermotolerance of fungal biocontrol agent Beauveria bassiana.Modulation of Alp4 function in Schizosaccharomyces pombe induces novel phenotypes that imply distinct functions for nuclear and cytoplasmic gamma-tubulin complexes.The carboxy-terminus of Alp4 alters microtubule dynamics to induce oscillatory nuclear movement led by the spindle pole body in Schizosaccharomyces pombe
P2860
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P2860
Alanine-scanning mutagenesis of Aspergillus gamma-tubulin yields diverse and novel phenotypes
description
2001 nî lūn-bûn
@nan
2001 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Alanine-scanning mutagenesis o ...... s diverse and novel phenotypes
@ast
Alanine-scanning mutagenesis o ...... s diverse and novel phenotypes
@en
type
label
Alanine-scanning mutagenesis o ...... s diverse and novel phenotypes
@ast
Alanine-scanning mutagenesis o ...... s diverse and novel phenotypes
@en
prefLabel
Alanine-scanning mutagenesis o ...... s diverse and novel phenotypes
@ast
Alanine-scanning mutagenesis o ...... s diverse and novel phenotypes
@en
P2093
P2860
P356
P1476
Alanine-scanning mutagenesis o ...... s diverse and novel phenotypes
@en
P2093
B R Oakley
C E Oakley
N Prigozhina
P2860
P304
P356
10.1091/MBC.12.7.2119
P577
2001-07-01T00:00:00Z