The NC2 repressor is dispensable in yeast mutated for the Sin4p component of the holoenzyme and plays roles similar to Mot1p in vivo.
about
NC2alpha interacts with BTAF1 and stimulates its ATP-dependent association with TATA-binding proteinGlobal distribution of negative cofactor 2 subunit-alpha on human promotersDirect stimulation of transcription by negative cofactor 2 (NC2) through TATA-binding protein (TBP)Cooperative action of NC2 and Mot1p to regulate TATA-binding protein function across the genomeThe yeast RNA polymerase II-associated factor Iwr1p is involved in the basal and regulated transcription of specific genes.Genetic analysis connects SLX5 and SLX8 to the SUMO pathway in Saccharomyces cerevisiae.The dual control of TFIIB recruitment by NC2 is gene specific.Mot1 activates and represses transcription by direct, ATPase-dependent mechanisms.Hypoxia actively represses transcription by inducing negative cofactor 2 (Dr1/DrAP1) and blocking preinitiation complex assemblyEfficient binding of NC2.TATA-binding protein to DNA in the absence of TATAMot1 regulates the DNA binding activity of free TATA-binding protein in an ATP-dependent manner.Mapping and functional characterization of the TAF11 interaction with TFIIA.Yeast NC2 associates with the RNA polymerase II preinitiation complex and selectively affects transcription in vivo.Mot1 associates with transcriptionally active promoters and inhibits association of NC2 in Saccharomyces cerevisiae.Multiple functions of the nonconserved N-terminal domain of yeast TATA-binding protein.Reconstitution of active human core Mediator complex reveals a critical role of the MED14 subunit.An early function during transcription for the yeast mRNA export factor Dbp5p/Rat8p suggested by its genetic and physical interactions with transcription factor IIH componentsThe critical cis-acting element required for IMD2 feedback regulation by GDP is a TATA box located 202 nucleotides upstream of the transcription start siteTranscription initiation of the yeast IMD2 gene is abolished in response to nutrient limitation through a sequence in its coding region.The NC2 alpha and beta subunits play different roles in vivo.TBP, Mot1, and NC2 establish a regulatory circuit that controls DPE-dependent versus TATA-dependent transcriptionRegulation of nuclear import and export of negative cofactor 2Ncb2 is involved in activated transcription of CDR1 in azole-resistant clinical isolates of Candida albicans.Dr1 (NC2) is present at tRNA genes and represses their transcription in human cells.Specific defects in different transcription complexes compensate for the requirement of the negative cofactor 2 repressor in Saccharomyces cerevisiae.Saccharomyces cerevisiae Ccr4-not complex contributes to the control of Msn2p-dependent transcription by the Ras/cAMP pathway.
P2860
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P2860
The NC2 repressor is dispensable in yeast mutated for the Sin4p component of the holoenzyme and plays roles similar to Mot1p in vivo.
description
2000 nî lūn-bûn
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2000年の論文
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The NC2 repressor is dispensab ...... oles similar to Mot1p in vivo.
@ast
The NC2 repressor is dispensab ...... oles similar to Mot1p in vivo.
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type
label
The NC2 repressor is dispensab ...... oles similar to Mot1p in vivo.
@ast
The NC2 repressor is dispensab ...... oles similar to Mot1p in vivo.
@en
prefLabel
The NC2 repressor is dispensab ...... oles similar to Mot1p in vivo.
@ast
The NC2 repressor is dispensab ...... oles similar to Mot1p in vivo.
@en
P2093
P2860
P1476
The NC2 repressor is dispensab ...... oles similar to Mot1p in vivo.
@en
P2093
P2860
P304
P356
10.1046/J.1365-2958.2000.01839.X
P407
P577
2000-04-01T00:00:00Z