Multiple active states and oligomerization of CCR5 revealed by functional properties of monoclonal antibodies. - Wikidata - wikimedia - TriplyDB

Multiple active states and oligomerization of CCR5 revealed by functional properties of monoclonal antibodies.

Multiple active states and oligomerization of CCR5 revealed by functional properties of monoclonal antibodies.

http://www.wikidata.org/entity/Q30857101

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CCR5 monoclonal antibodies for HIV-1 therapy Allosteric potentiators of metabotropic glutamate receptor subtype 1a differentially modulate independent signaling pathways in baby hamster kidney cells Opportunities for functional selectivity in GPCR antibodies P2X1 Receptor Antagonists Inhibit HIV-1 Fusion by Blocking Virus-Coreceptor Interactions Dopamine receptor activation increases HIV entry into primary human macrophages A single-residue change in the HIV-1 V3 loop associated with maraviroc resistance impairs CCR5 binding affinity while increasing replicative capacity.Chemokine receptor oligomerization and allostery.Constrained use of CCR5 on CD4+ lymphocytes by R5X4 HIV-1: efficiency of Env-CCR5 interactions and low CCR5 expression determine a range of restricted CCR5-mediated entry.Role of antibodies in developing drugs that target G-protein-coupled receptor dimers.CCR5 expression levels influence NFAT translocation, IL-2 production, and subsequent signaling events during T lymphocyte activation.The antibodies against the computationally designed mimic of the glycoprotein hormone receptor transmembrane domain provide insights into receptor activation and suppress the constitutively activated receptor mutants.New insights into the mechanisms whereby low molecular weight CCR5 ligands inhibit HIV-1 infection The isolation of novel phage display-derived human recombinant antibodies against CCR5, the major co-receptor of HIV Natural anti-CCR5 antibodies in HIV-infection and -exposure CCR5 conformations are dynamic and modulated by localization, trafficking and G protein association CCR5: From Natural Resistance to a New Anti-HIV Strategy.Conformational dynamics of single G protein-coupled receptors in solution Long-lasting CCR5 internalization by antibodies in a subset of long-term nonprogressors: a possible protective effect against disease progression Susceptibility of HIV type 2 primary isolates to CCR5 and CXCR4 monoclonal antibodies, ligands, and small molecule inhibitors CCR5 susceptibility to ligand-mediated down-modulation differs between human T lymphocytes and myeloid cells.Stimulus bias provides evidence for conformational constraints in the structure of a G protein-coupled receptor Functional monoclonal antibody acts as a biased agonist by inducing internalization of metabotropic glutamate receptor 7.Receptors as microprocessors: pharmacological nuance on metabotropic glutamate receptors 1alpha.Therapeutic potential of β-arrestin- and G protein-biased agonists.Highly potent, fully recombinant anti-HIV chemokines: reengineering a low-cost microbicide.Antibodies against G-protein coupled receptors: novel uses in screening and drug development.Heterosexual transmission of human immunodeficiency virus type 1 subtype C: Macrophage tropism, alternative coreceptor use, and the molecular anatomy of CCR5 utilization.Conformation state-sensitive antibodies to G-protein-coupled receptors.Class B β-arrestin2-dependent CCR5 signalosome retention with natural antibodies to CCR5.HIV-1 Nef down-modulates C-C and C-X-C chemokine receptors via ubiquitin and ubiquitin-independent mechanism Induction of HIV-blocking anti-CCR5 IgA in Peyers's patches without histopathological alterations.Chemokines and their receptors in the allergic airway inflammatory process.Immunotherapeutic restoration in HIV-infected individuals.HIV-1 Entry, Inhibitors, and Resistance Allosteric and biased g protein-coupled receptor signaling regulation: potentials for new therapeutics.New paradigms in chemokine receptor signal transduction: Moving beyond the two-site model.Activation of CCR5 by chemokines involves an aromatic cluster between transmembrane helices 2 and 3.Blocking HIV-1 infection via CCR5 and CXCR4 receptors by acting in trans on the CCR2 chemokine receptor.Properties of 7ND-CCL2 are modulated upon fusion to Fc.Video views and reviews.

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P2860

Multiple active states and oligomerization of CCR5 revealed by functional properties of monoclonal antibodies.

http://www.wikidata.org/entity/Q30857101

description

2002 nî lūn-bûn

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2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի փետրվարին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

Multiple active states and oli ...... ties of monoclonal antibodies.

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Multiple active states and oli ...... ties of monoclonal antibodies.

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type

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Multiple active states and oli ...... ties of monoclonal antibodies.

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Multiple active states and oli ...... ties of monoclonal antibodies.

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Multiple active states and oli ...... ties of monoclonal antibodies.

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Multiple active states and oli ...... ties of monoclonal antibodies.

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Molecular Biology of the Cell

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Multiple active states and oli ...... ties of monoclonal antibodies.

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P2093

Cédric Blanpain

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Detlef Schlndorff

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Emmanuel Le Poul

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Gilbert Vassart

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Hassan Issafras

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Jean-Marie Vanderwinden

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Josef Cihak

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Manfred Stangassinger

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Marc Parmentier

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Matthias Mack

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P2860

Arrestin binding to the G protein-coupled N-formyl peptide receptor is regulated by the conserved "DRY" sequence

AT1-receptor heterodimers show enhanced G-protein activation and altered receptor sequestration

Molecular cloning and functional expression of a new human CC-chemokine receptor gene

Characterization of the CCR2 chemokine receptor: functional CCR2 receptor expression in B cells

Subtypes of the somatostatin receptor assemble as functional homo- and heterodimers

International union of pharmacology. XXII. Nomenclature for chemokine receptors

Chemokines and disease

New targets for inhibitors of HIV-1 replication

Monitoring receptor oligomerization using time-resolved fluorescence resonance energy transfer and bioluminescence resonance energy transfer. The human delta -opioid receptor displays constitutive oligomerization at the cell surface, which is not re

Constitutive and agonist-dependent homo-oligomerization of the thyrotropin-releasing hormone receptor. Detection in living cells using bioluminescence resonance energy transfer

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723-737

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scholarly article

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10.1091/MBC.01-03-0129

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2

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13

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Stefano Marullo

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2002-02-01T00:00:00Z

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11507981

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11854425

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65662

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