Syntrophin gamma 2 regulates SCN5A gating by a PDZ domain-mediated interaction.
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Voltage-gated ion channel dysfunction precedes cardiomyopathy development in the dystrophic heartalpha-1-syntrophin mutation and the long-QT syndrome: a disease of sodium channel disruptionPhysiological and Pathophysiological Insights of Nav1.4 and Nav1.5 ComparisonChannelopathies from mutations in the cardiac sodium channel protein complexA mutation in telethonin alters Nav1.5 functionInteraction of alpha1-syntrophin with multiple isoforms of heterotrimeric G protein alpha subunitsTyrosine-phosphorylated and nonphosphorylated sodium channel beta1 subunits are differentially localized in cardiac myocytesDecreased inward rectifier potassium current IK1 in dystrophin-deficient ventricular cardiomyocytes.Transcriptome profiling of the demosponge Amphimedon queenslandica reveals genome-wide events that accompany major life cycle transitions.Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin.Diseases caused by mutations in Nav1.5 interacting proteinsHuman macrophage SCN5A activates an innate immune signaling pathway for antiviral host defense.The PDZ motif of the α1C subunit is not required for surface trafficking and adrenergic modulation of CaV1.2 channel in the heart.The Relationship Between Gastric Myoelectric Activity and SCN5A Mutation Suggesting Sodium Channelopathy in Patients With Brugada Syndrome and Functional Dyspepsia - A Pilot Study.Nav channel mechanosensitivity: activation and inactivation accelerate reversibly with stretch."CRASH"ing with the worm: insights into L1CAM functions and mechanisms.Membrane tension accelerates rate-limiting voltage-dependent activation and slow inactivation steps in a Shaker channelQuantification of gastrointestinal sodium channelopathy.Mechanosensitive ion channels in interstitial cells of Cajal and smooth muscle of the gastrointestinal tract.unc-44 Ankyrin and stn-2 gamma-syntrophin regulate sax-7 L1CAM function in maintaining neuronal positioning in Caenorhabditis elegansAlternative splicing regulates activation-induced cytidine deaminase (AID): implications for suppression of AID mutagenic activity in normal and malignant B cells.Sodium channel mutation in irritable bowel syndrome: evidence for an ion channelopathy.A novel mechanism for the treatment of angina, arrhythmias, and diastolic dysfunction: inhibition of late I(Na) using ranolazine.Dysfunction in ankyrin-based cellular pathways and human cardiac arrhythmia.Biology of cardiac sodium channel Nav1.5 expression.Targeting ion channels for the treatment of gastrointestinal motility disordersGastrointestinal motility and its enteric actors in mechanosensitivity: past and present.Late sodium current: A mechanism for angina, heart failure, and arrhythmia.Ranolazine inhibits shear sensitivity of endogenous Na+ current and spontaneous action potentials in HL-1 cells.Regulation of TRPC1 and TRPC4 cation channels requires an alpha1-syntrophin-dependent complex in skeletal mouse myotubes.Modulation of host gene expression by the K15 protein of Kaposi's sarcoma-associated herpesvirus.Cytoskeletal basis of ion channel function in cardiac muscle.Membrane permeable local anesthetics modulate Na(V)1.5 mechanosensitivityRanolazine decreases mechanosensitivity of the voltage-gated sodium ion channel Na(v)1.5: a novel mechanism of drug action.Mechanosensitivity of Nav1.5, a voltage-sensitive sodium channel.Hydrogen sulfide is a partially redox-independent activator of the human jejunum Na+ channel, Nav1.5.Infant sudden death: Mutations responsible for impaired Nav1.5 channel trafficking and function.Distribution and function of voltage-gated sodium channels in the nervous system.Fluid flow modulates electrical activity in cardiac hERG potassium channels.Species dependent expression of intestinal smooth muscle mechanosensitive sodium channels.
P2860
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P2860
Syntrophin gamma 2 regulates SCN5A gating by a PDZ domain-mediated interaction.
description
2002 nî lūn-bûn
@nan
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Syntrophin gamma 2 regulates SCN5A gating by a PDZ domain-mediated interaction.
@ast
Syntrophin gamma 2 regulates SCN5A gating by a PDZ domain-mediated interaction.
@en
type
label
Syntrophin gamma 2 regulates SCN5A gating by a PDZ domain-mediated interaction.
@ast
Syntrophin gamma 2 regulates SCN5A gating by a PDZ domain-mediated interaction.
@en
prefLabel
Syntrophin gamma 2 regulates SCN5A gating by a PDZ domain-mediated interaction.
@ast
Syntrophin gamma 2 regulates SCN5A gating by a PDZ domain-mediated interaction.
@en
P2093
P2860
P356
P1476
Syntrophin gamma 2 regulates SCN5A gating by a PDZ domain-mediated interaction.
@en
P2093
Gianrico Farrugia
Jonathan Makielski
Michael Ackerman
Peter Strege
Simon J Gibbons
Steven M Miller
P2860
P304
P356
10.1074/JBC.M209938200
P407
P577
2002-11-11T00:00:00Z