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Involvement of human MOF in ATM functionRadiation and breast cancer: a review of current evidenceCommon ataxia telangiectasia mutated haplotypes and risk of breast cancer: a nested case-control studyAtaxia telangiectasia mutated (ATM) kinase and ATM and Rad3 related kinase mediate phosphorylation of Brca1 at distinct and overlapping sites. In vivo assessment using phospho-specific antibodiesAspirin blocks proliferation in colon cells by inducing a G1 arrest and apoptosis through activation of the checkpoint kinase ATMHemizygosity for Atm and Brca1 influence the balance between cell transformation and apoptosis.ATM modulates the loading of recombination proteins onto a chromosomal translocation breakpoint hotspot.Atm heterozygous mice are more sensitive to radiation-induced cataracts than are their wild-type counterparts.Chromosome instability in human lung cancers: possible underlying mechanisms and potential consequences in the pathogenesis.Multifunctional role of ATM/Tel1 kinase in genome stability: from the DNA damage response to telomere maintenanceMetastasis of neuroendocrine tumors are characterized by increased cell proliferation and reduced expression of the ATM geneATM, a central controller of cellular responses to DNA damage.ATM activation in the presence of oxidative stress.Mitogen-activated protein kinase activation in UV-induced signal transduction.Genetic polymorphisms and gene-dosage effect in ovarian cancer risk and response to paclitaxel/cisplatin chemotherapyGenes and pathways driving glioblastomas in humans and murine disease models.Molecular basis of mantle cell lymphoma.The ATM missense mutation p.Ser49Cys (c.146C>G) and the risk of breast cancer.Comparative genomic hybridization identifies loss of 18q22-qter as an early and specific event in tumorigenesis of midgut carcinoidsBridging the gap between in vitro and in vivo: Dose and schedule predictions for the ATR inhibitor AZD6738Breast cancer susceptibility and the DNA damage response.miR-214-mediated downregulation of RNF8 induces chromosomal instability in ovarian cancer cellsGenetic susceptibility to iatrogenic malignancy.ATM haplotypes and breast cancer risk in Jewish high-risk women.Neurons in Vulnerable Regions of the Alzheimer's Disease Brain Display Reduced ATM Signaling.Recent progress in mouse models for tumor suppressor genes and its implications in human cancer.Genetic variations in DNA repair genes, radiosensitivity to cancer and susceptibility to acute tissue reactions in radiotherapy-treated cancer patients.RADIOSENSITIVITY TO HIGH ENERGY IRON IONS IS INFLUENCED BY HETEROZYGOSITY for ATM, RAD9 and BRCA1.Skin: A mirror of internal malignancy.Connecting the Dots: Interplay between Ubiquitylation and SUMOylation at DNA Double-Strand BreaksDouble-strand breaks and the concept of short- and long-term epigenetic memory.DNA repair: the link between primary immunodeficiency and cancer.Aberrant methylation of the ATM promoter correlates with increased radiosensitivity in a human colorectal tumor cell line.Doxorubicin activates ATM-dependent phosphorylation of multiple downstream targets in part through the generation of reactive oxygen species.Recent advances in targeting DNA repair pathways for the treatment of ovarian cancer and their clinical relevance.Alterations of ATM and CADM1 in chromosomal 11q22.3-23.2 region are associated with the development of invasive cervical carcinoma.Chk2 activation and phosphorylation-dependent oligomerization.Induction of base damages representing a high risk site for double-strand DNA break formation in genomic DNA by exposure of cells to DNA damaging agents.Analysis of secondary V(D)J rearrangements in mature, peripheral T cells of ataxia-telangiectasia heterozygotes.Signal transduction through the B cell antigen receptor is normal in ataxia-telangiectasia B lymphocytes.
P2860
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P2860
description
2000 nî lūn-bûn
@nan
2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Cancer risk and the ATM gene: a continuing debate.
@ast
Cancer risk and the ATM gene: a continuing debate.
@en
type
label
Cancer risk and the ATM gene: a continuing debate.
@ast
Cancer risk and the ATM gene: a continuing debate.
@en
prefLabel
Cancer risk and the ATM gene: a continuing debate.
@ast
Cancer risk and the ATM gene: a continuing debate.
@en
P2860
P356
P1476
Cancer risk and the ATM gene: a continuing debate.
@en
P2093
P2860
P304
P356
10.1093/JNCI/92.10.795
P407
P577
2000-05-01T00:00:00Z