The orexin OX1 receptor activates a novel Ca2+ influx pathway necessary for coupling to phospholipase C.
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Physiology of the orexinergic/hypocretinergic system: a revisit in 2012The role of orexin in post-stroke inflammation, cognitive decline, and depressionRole of orexin receptors in obesity: from cellular to behavioral evidenceOX1 orexin receptors couple to adenylyl cyclase regulation via multiple mechanismsOrexin A and B evoke noradrenaline release from rat cerebrocortical slicesOrexin-A induces anxiety-like behavior through interactions with glutamatergic receptors in the bed nucleus of the stria terminalis of ratsOrexin signaling in recombinant neuron-like cells.Phospholipase C activator m-3M3FBS affects Ca2+ homeostasis independently of phospholipase C activationShort food deprivation inhibits orexin receptor 1 expression and orexin-A induced intracellular calcium signaling in acutely isolated duodenal enterocytes.Immunoprofiling of Adult-Derived Human Liver Stem/Progenitor Cells: Impact of Hepatogenic Differentiation and InflammationOrexins/hypocretins: waking up the scientific world.Mapping of the mRNAs for the hypocretin/orexin and melanin-concentrating hormone receptors: networks of overlapping peptide systems.Hypocretin-1 causes G protein activation and increases ACh release in rat pons.Functions of the orexinergic/hypocretinergic system.Activation of orexin 1 receptors in the periaqueductal gray of male rats leads to antinociception via retrograde endocannabinoid (2-arachidonoylglycerol)-induced disinhibition.OX1 orexin/hypocretin receptor activation of phospholipase D.Brain orexin promotes obesity resistance.Orexin receptor agonist Yan 7874 is a weak agonist of orexin/hypocretin receptors and shows orexin receptor-independent cytotoxicity.Orexin: pathways to obesity resistance?Dual orexin actions on dorsal raphe and laterodorsal tegmentum neurons: noisy cation current activation and selective enhancement of Ca2+ transients mediated by L-type calcium channels.Hypocretin/Orexin neuropeptides: participation in the control of sleep-wakefulness cycle and energy homeostasis.Differential actions of orexin receptors in brainstem cholinergic and monoaminergic neurons revealed by receptor knockouts: implications for orexinergic signaling in arousal and narcolepsy.Microarray-assisted fine mapping of quantitative trait loci on chromosome 15 for susceptibility to seizure-induced cell death in mice.Orexin/hypocretin receptor signalling: a functional perspective.Orexin 1 receptor antagonists in compulsive behavior and anxiety: possible therapeutic use.Central functions of the orexinergic system.Orexin/hypocretin receptor signalling cascades.Orexin/hypocretin based pharmacotherapies for the treatment of addiction: DORA or SORA?The hypocretin/orexin system: an increasingly important role in neuropsychiatry.Orexin/hypocretin activates mTOR complex 1 (mTORC1) via an Erk/Akt-independent and calcium-stimulated lysosome v-ATPase pathway.Genomic organization and regulation of the human orexin (hypocretin) receptor 2 gene: identification of alternative promoters.The sustainability of interactions between the orexin-1 receptor and beta-arrestin-2 is defined by a single C-terminal cluster of hydroxy amino acids and modulates the kinetics of ERK MAPK regulation.Orphan G protein-coupled receptor, GPR41, induces apoptosis via a p53/Bax pathway during ischemic hypoxia and reoxygenation.Regulation of OX1 orexin/hypocretin receptor-coupling to phospholipase C by Ca2+ influx.Orexins protect neuronal cell cultures against hypoxic stress: an involvement of Akt signalingIn the presence of L-NAME SERCA blockade induces endothelium-dependent contraction of mouse aorta through activation of smooth muscle prostaglandin H2/thromboxane A2 receptors.Arachidonic acid release mediated by OX1 orexin receptors.G-protein-coupled OX1 orexin/hcrtr-1 hypocretin receptors induce caspase-dependent and -independent cell death through p38 mitogen-/stress-activated protein kinase.Expression of orexin A and its receptor 1 in the human prostate.Calcium affects OX1 orexin (hypocretin) receptor responses by modifying both orexin binding and the signal transduction machinery.
P2860
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P2860
The orexin OX1 receptor activates a novel Ca2+ influx pathway necessary for coupling to phospholipase C.
description
2000 nî lūn-bûn
@nan
2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
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2000年论文
@wuu
name
The orexin OX1 receptor activa ...... r coupling to phospholipase C.
@ast
The orexin OX1 receptor activa ...... r coupling to phospholipase C.
@en
type
label
The orexin OX1 receptor activa ...... r coupling to phospholipase C.
@ast
The orexin OX1 receptor activa ...... r coupling to phospholipase C.
@en
prefLabel
The orexin OX1 receptor activa ...... r coupling to phospholipase C.
@ast
The orexin OX1 receptor activa ...... r coupling to phospholipase C.
@en
P2093
P2860
P356
P1476
The orexin OX1 receptor activa ...... or coupling to phospholipase C
@en
P2093
Akerman KE
Kukkonen JP
Shariatmadari R
P2860
P304
30806-30812
P356
10.1074/JBC.M002603200
P407
P50
P577
2000-10-01T00:00:00Z