High-density mutagenesis by combined DNA shuffling and phage display to assign essential amino acid residues in protein-protein interactions: application to study structure-function of plasminogen activation inhibitor 1 (PAI-I).
about
Structural consequences of target epitope-directed functional alteration of an antibody. The case of anti-hen lysozyme antibody, HyHEL-10Recombinant single-chain variable fragment antibodies directed against Clostridium difficile toxin B produced by use of an optimized phage display systemLaboratory-directed protein evolutionRetention of thrombin inhibitory activity by recombinant serpins expressed as integral membrane proteins tethered to the surface of mammalian cells.Survey of the year 2000 commercial optical biosensor literature.Phage display of the serpin alpha-1 proteinase inhibitor randomized at consecutive residues in the reactive centre loop and biopanned with or without thrombin.Sex in a test tube: testing the benefits of in vitro recombination.The length of the reactive center loop modulates the latency transition of plasminogen activator inhibitor-1.Structural factors affecting the choice between latency transition and polymerization in inhibitory serpins.The distal hinge of the reactive site loop and its proximity: a target to modulate plasminogen activator inhibitor-1 activity.Mapping of the epitope of a monoclonal antibody protecting plasminogen activator inhibitor-1 against inactivating agents.Mutational analysis of plasminogen activator inhibitor-1.
P2860
Q27641047-2ECBFC6B-2BA0-4AB8-AB29-D9EAE10CEE2BQ30782773-58B22D9F-9E04-4636-B1B6-B81C7594C1C0Q33222949-BB5F0A1F-2F2A-4D03-A1EC-758D25BA9095Q34040373-9DEA6792-6B0A-4A0B-94D2-5E64DD2E9836Q34464911-3C33BDD1-B429-4B29-AE0D-E267E0EDC117Q37464698-6FB880D5-77BE-4F2F-8C76-692A4D703921Q38952339-C2B346D0-006F-4477-9CDE-B6BED89E2F64Q41857439-39B456F4-F599-4FA0-8736-07FDF4C310FBQ41869912-E6B0AF34-C57B-4E7E-8997-DB9D2ADBA7FAQ43739493-19DF7060-190B-4575-9EB2-DFC00E58E93FQ44402629-C9F91AAA-0678-4A16-B861-3C4A7941C547Q44402632-E6AA875E-9DE2-4366-86AC-BA64947B1496
P2860
High-density mutagenesis by combined DNA shuffling and phage display to assign essential amino acid residues in protein-protein interactions: application to study structure-function of plasminogen activation inhibitor 1 (PAI-I).
description
2000 nî lūn-bûn
@nan
2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
High-density mutagenesis by co ...... ctivation inhibitor 1 (PAI-I).
@ast
High-density mutagenesis by co ...... ctivation inhibitor 1 (PAI-I).
@en
type
label
High-density mutagenesis by co ...... ctivation inhibitor 1 (PAI-I).
@ast
High-density mutagenesis by co ...... ctivation inhibitor 1 (PAI-I).
@en
prefLabel
High-density mutagenesis by co ...... ctivation inhibitor 1 (PAI-I).
@ast
High-density mutagenesis by co ...... ctivation inhibitor 1 (PAI-I).
@en
P2093
P356
P1476
High-density mutagenesis by co ...... ctivation inhibitor 1 (PAI-I).
@en
P2093
P304
P356
10.1006/JMBI.2000.4035
P407
P577
2000-09-01T00:00:00Z