DNA microarray profiling of genes differentially regulated by the histone deacetylase inhibitors vorinostat and LBH589 in colon cancer cell lines. - Wikidata - wikimedia - TriplyDB

DNA microarray profiling of genes differentially regulated by the histone deacetylase inhibitors vorinostat and LBH589 in colon cancer cell lines.

DNA microarray profiling of genes differentially regulated by the histone deacetylase inhibitors vorinostat and LBH589 in colon cancer cell lines.

http://www.wikidata.org/entity/Q30931932

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A novel small molecule hydroxamate preferentially inhibits HDAC6 activity and tumour growth HDAC Inhibitors as Epigenetic Regulators of the Immune System: Impacts on Cancer Therapy and Inflammatory Diseases Mechanisms of Histone Deacetylase Inhibitor-Regulated Gene Expression in Cancer Cells Elevated peritoneal fluid TNF-α incites ovarian early growth response factor 1 expression and downstream protease mediators: a correlation with ovulatory dysfunction in endometriosis.Romidepsin in peripheral and cutaneous T-cell lymphoma: mechanistic implications from clinical and correlative data The HDAC inhibitor LBH589 (panobinostat) is an inhibitory modulator of aromatase gene expression.Histone deacetylase inhibition synergistically enhances pemetrexed cytotoxicity through induction of apoptosis and autophagy in non-small cell lung cancer.Toll-like signaling and the cytokine IL-6 regulate histone deacetylase dependent neuronal survival Histone Deacetylase Inhibitors: Advancing Therapeutic Strategies in Hematological and Solid Malignancies.Histone deacetylase (HDAC) inhibitors in recent clinical trials for cancer therapy.Loss-of-function RNAi screens in breast cancer cells identify AURKB, PLK1, PIK3R1, MAPK12, PRKD2, and PTK6 as sensitizing targets of rapamycin activity The dual EGFR/HER2 inhibitor lapatinib synergistically enhances the antitumor activity of the histone deacetylase inhibitor panobinostat in colorectal cancer models.Radiosensitization of glioblastoma cells using a histone deacetylase inhibitor (SAHA) comparing carbon ions with X-rays.Emerging therapeutics for advanced thyroid malignancies: rationale and targeted approaches.DNA methylation and histone modifications regulate SOX11 expression in lymphoid and solid cancer cells.Metabolism as a key to histone deacetylase inhibition.Microarray gene expression profiling reveals potential mechanisms of tumor suppression by the class I HDAC-selective benzoylhydrazide inhibitors.Inhibition of the proliferation of acquired aromatase inhibitor-resistant breast cancer cells by histone deacetylase inhibitor LBH589 (panobinostat).Concerted changes in transcriptional regulation of genes involved in DNA methylation, demethylation, and folate-mediated one-carbon metabolism pathways in the NCI-60 cancer cell line panel in response to cancer drug treatment Hepatic stem cells and transforming growth factor β in hepatocellular carcinoma Suberoylanilide hydroxamic acid induces limited changes in the transcriptome of primary CD4(+) T cells.Histone deacetylase inhibition promotes osteoblast maturation by altering the histone H4 epigenome and reduces Akt phosphorylation.Influence of a novel histone deacetylase inhibitor panobinostat (LBH589) on the growth of ovarian cancer.Profile of panobinostat and its potential for treatment in solid tumors: an update.Erasers of histone acetylation: the histone deacetylase enzymes.Targeting histone deacetylases: development of vorinostat for the treatment of cancer.Preclinical activity of LBH589 alone or in combination with chemotherapy in a xenogeneic mouse model of human acute lymphoblastic leukemia.Mixed effects of suberoylanilide hydroxamic acid (SAHA) on the host transcriptome and proteome and their implications for HIV reactivation from latency.Epigenetic drugs for cancer treatment and prevention: mechanisms of action.The histone deacetylase inhibitor PXD101 increases the efficacy of irinotecan in in vitro and in vivo colon cancer models.Epigenetic modulation with histone deacetylase inhibitors in combination with immunotherapy.Transcriptional Selectivity of Epigenetic Therapy in Cancer.Selective inhibition of esophageal cancer cells by combination of HDAC inhibitors and Azacytidine DNA Hypomethylating Drugs in Cancer Therapy.Basic nuclear processes affected by histone acetyltransferases and histone deacetylase inhibitors.The histone deacetylase inhibitor vorinostat prevents TNFα-induced necroptosis by regulating multiple signaling pathways.Sustained inhibition of deacetylases is required for the antitumor activity of the histone deactylase inhibitors panobinostat and vorinostat in models of colorectal cancer.DAPK plays an important role in panobinostat-induced autophagy and commits cells to apoptosis under autophagy deficient conditions.Transcriptional regulation of Nox4 by histone deacetylases in human endothelial cells.Novel α-substituted tropolones promote potent and selective caspase-dependent leukemia cell apoptosis.

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DNA microarray profiling of genes differentially regulated by the histone deacetylase inhibitors vorinostat and LBH589 in colon cancer cell lines.

http://www.wikidata.org/entity/Q30931932

description

2009 nî lūn-bûn

@nan

2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

DNA microarray profiling of ge ...... 89 in colon cancer cell lines.

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DNA microarray profiling of ge ...... 89 in colon cancer cell lines.

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type

label

DNA microarray profiling of ge ...... 89 in colon cancer cell lines.

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DNA microarray profiling of ge ...... 89 in colon cancer cell lines.

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prefLabel

DNA microarray profiling of ge ...... 89 in colon cancer cell lines.

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DNA microarray profiling of ge ...... 89 in colon cancer cell lines.

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Robert D Ladner

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P2860

Aven, a novel inhibitor of caspase activation, binds Bcl-xL and Apaf-1

HDAC6 is a microtubule-associated deacetylase

A nuclear protein, synthesized in growth-arrested human hepatoblastoma cells, is a novel member of the short-chain alcohol dehydrogenase family

Metallothionein 1G acts as an oncosupressor in papillary thyroid carcinoma

Identification of a novel nuclear protein synthesized in growth-arrested human hepatoblastoma HepG2 cells

Histone deacetylase 3 localizes to the mitotic spindle and is required for kinetochore-microtubule attachment.

Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial

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