Cell surface-bound heat shock protein 70 (Hsp70) mediates perforin-independent apoptosis by specific binding and uptake of granzyme B. - Wikidata - wikimedia - TriplyDB

Cell surface-bound heat shock protein 70 (Hsp70) mediates perforin-independent apoptosis by specific binding and uptake of granzyme B.

Cell surface-bound heat shock protein 70 (Hsp70) mediates perforin-independent apoptosis by specific binding and uptake of granzyme B.

http://www.wikidata.org/entity/Q30967103

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Heat Shock Protein-Peptide and HSP-Based Immunotherapies for the Treatment of Cancer Heat Shock Protein 70 (Hsp70) Peptide Activated Natural Killer (NK) Cells for the Treatment of Patients with Non-Small Cell Lung Cancer (NSCLC) after Radiochemotherapy (RCTx) - From Preclinical Studies to a Clinical Phase II Trial Irradiation-induced up-regulation of HLA-E on macrovascular endothelial cells confers protection against killing by activated natural killer cells The human HSP70 family of chaperones: where do we stand?Heat shock proteins and heat shock factor 1 in carcinogenesis and tumor development: an update Immunotherapeutic targeting of membrane Hsp70-expressing tumors using recombinant human granzyme B Correlation of Hsp70 Serum Levels with Gross Tumor Volume and Composition of Lymphocyte Subpopulations in Patients with Squamous Cell and Adeno Non-Small Cell Lung Cancer.Granzyme B produced by human plasmacytoid dendritic cells suppresses T-cell expansion.Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia.Plasmodium falciparum-infected erythrocytes induce granzyme B by NK cells through expression of host-Hsp70.Trichosanthin increases Granzyme B penetration into tumor cells by upregulation of CI-MPR on the cell surface Cationic sites on granzyme B contribute to cytotoxicity by promoting its uptake into target cells.Tumor imaging and targeting potential of an Hsp70-derived 14-mer peptide.Delivery and therapeutic potential of human granzyme B.Circulating heat shock protein 70 and progression in patients with chronic myeloid leukemia.Inducible heat shock protein 70 expression as a potential predictive marker of metastasis in breast tumors.Prediction of the clinical outcome in invasive candidiasis patients based on molecular fingerprints of five anti-Candida antibodies in serum Death by a thousand cuts: granzyme pathways of programmed cell death Intracellular versus extracellular granzyme B in immunity and disease: challenging the dogma.HSP70s: From Tumor Transformation to Cancer Therapy.Insulin-degrading enzyme sorting in exosomes: a secretory pathway for a key brain amyloid-beta degrading protease Surface expression of Hsp25 and Hsp72 differentially regulates tumor growth and metastasis.Chaperokine-induced signal transduction pathways.Chaperone proteins and brain tumors: potential targets and possible therapeutics.Dendritic cell activation and maturation induced by recombinant calreticulin fragment 39-272.Chronic inflammation in cancer development.A Novel Strategy for TNF-Alpha Production by 2-APB Induced Downregulated SOCE and Upregulated HSP70 in O. tsutsugamushi-Infected Human Macrophages Therapeutic aspects of chaperones/heat-shock proteins in neuro-oncology.Transport capabilities of eleven gram-positive bacteria: comparative genomic analyses.Heat shock proteins in cancer.Dissecting the role of hyperthermia in natural killer cell mediated anti-tumor responses.Membranes: a meeting point for lipids, proteins and therapies The therapeutic implications of clinically applied modifiers of heat shock protein 70 (Hsp70) expression by tumor cells.Influence of Hsp70 and HLA-E on the killing of leukemic blasts by cytokine/Hsp70 peptide-activated human natural killer (NK) cells.Heat-shock proteins in cancer vaccines: agents of antigen cross-presentation.Heat-shock proteins as powerful weapons in vaccine development.Lytic granule polarization, rather than degranulation, is the preferred target of inhibitory receptors in NK cells.The battlefield of perforin/granzyme cell death pathways.Molecular chaperones and protein-folding catalysts as intercellular signaling regulators in immunity and inflammation.Kill and spread the word: stimulation of antitumor immune responses in the context of radiotherapy.

P2860

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P2860

Cell surface-bound heat shock protein 70 (Hsp70) mediates perforin-independent apoptosis by specific binding and uptake of granzyme B.

http://www.wikidata.org/entity/Q30967103

description

2003 nî lūn-bûn

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2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի հուլիսին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

Cell surface-bound heat shock ...... ding and uptake of granzyme B.

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Cell surface-bound heat shock ...... ding and uptake of granzyme B.

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type

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Cell surface-bound heat shock ...... ding and uptake of granzyme B.

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Cell surface-bound heat shock ...... ding and uptake of granzyme B.

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prefLabel

Cell surface-bound heat shock ...... ding and uptake of granzyme B.

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Cell surface-bound heat shock ...... ding and uptake of granzyme B.

@en

P1433

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P1433

Journal of Biological Chemistry

P1476

Cell surface-bound heat shock ...... ding and uptake of granzyme B.

@en

P2093

Antonio DeMaio

http://www.w3.org/2001/XMLSchema#string

Catharina Gross

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Gabriele Multhoff

http://www.w3.org/2001/XMLSchema#string

Nelson Arispe

http://www.w3.org/2001/XMLSchema#string

Walter Koelch

http://www.w3.org/2001/XMLSchema#string

P2860

Granzyme B directly and efficiently cleaves several downstream caspase substrates: implications for CTL-induced apoptosis

The carboxy-terminal domain of Hsc70 provides binding sites for a distinct set of chaperone cofactors

Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex

Molecular chaperones in cellular protein folding

Stress proteins and immunity mediated by cytotoxic T lymphocytes.

Plasminogen activation in degradation and penetration of extracellular matrices and basement membranes by invasive bacteria.

Lymphocyte apoptosis: refining the paths to perdition.

HSP70 peptidembearing and peptide-negative preparations act as chaperokines.

Generation of cytotoxic T lymphocytes in vitro. II. Effect of repeated exposure to alloantigens on the cytotoxic activity of long-term mixed leukocyte cultures.

Lipid interaction differentiates the constitutive and stress-induced heat shock proteins Hsc70 and Hsp70.

P304

41173-41181

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scholarly article

P356

10.1074/JBC.M302644200

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P407

P433

42

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P478

278

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P577

2003-07-21T00:00:00Z

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P698

12874291

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