Identification of potential anticancer drug targets through the selection of growth-inhibitory genetic suppressor elements.
about
Large-scale exploration of growth inhibition caused by overexpression of genomic fragments in Saccharomyces cerevisiaeResponse projected clustering for direct association with physiological and clinical response dataTumor-specific silencing of COPZ2 gene encoding coatomer protein complex subunit ζ 2 renders tumor cells dependent on its paralogous gene COPZ1Selection-subtraction approach (SSA): a universal genetic screening technique that enables negative selectionIdentification of cell surface and secreted proteins essential for tumor cell survival using a genetic suppressor element screen.Phenotype-based identification of host genes required for replication of African swine fever virusIdentification of cellular genes affecting the infectivity of foot-and-mouth disease virus.Function-based gene identification using enzymatically generated normalized shRNA library and massive parallel sequencing.Soluble L1CAM promotes breast cancer cell adhesion and migration in vitro, but not invasion.Alternative ways of modulating JAK-STAT pathway: Looking beyond phosphorylation.Modification of the L1-CAM carboxy-terminus in pancreatic adenocarcinoma cellsFunctional interrogation of breast cancer: from models to drugs.Txr1: a transcriptional regulator of thrombospondin-1 that modulates cellular sensitivity to taxanes.A screen for genetic suppressor elements of hepatitis C virus identifies a supercharged protein inhibitor of viral replication.Impact of the N-Terminal Domain of STAT3 in STAT3-Dependent Transcriptional ActivityIdentification of novel cancer therapeutic targets using a designed and pooled shRNA library screenL1, a novel target of beta-catenin signaling, transforms cells and is expressed at the invasive front of colon cancersSTAT3 suppresses transcription of proapoptotic genes in cancer cells with the involvement of its N-terminal domainComparison of pancreas juice proteins from cancer versus pancreatitis using quantitative proteomic analysis.Nuclear translocation and signalling of L1-CAM in human carcinoma cells requires ADAM10 and presenilin/gamma-secretase activity.Drug target discovery using retroviruses.The cytoplasmic part of L1-CAM controls growth and gene expression in human tumors that is reversed by therapeutic antibodies.L1-CAM is commonly expressed in testicular germ cell tumours.
P2860
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P2860
Identification of potential anticancer drug targets through the selection of growth-inhibitory genetic suppressor elements.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Identification of potential an ...... y genetic suppressor elements.
@ast
Identification of potential an ...... y genetic suppressor elements.
@en
type
label
Identification of potential an ...... y genetic suppressor elements.
@ast
Identification of potential an ...... y genetic suppressor elements.
@en
prefLabel
Identification of potential an ...... y genetic suppressor elements.
@ast
Identification of potential an ...... y genetic suppressor elements.
@en
P2093
P1433
P1476
Identification of potential an ...... y genetic suppressor elements.
@en
P2093
Anil Maliyekkel
Bey Dih Chang
Igor B Roninson
Justin Sadhu
Mirza Baig
Sergey A Axenovich
Stacey Fellars
Tatyana A Holzmayer
Thomas Primiano
P356
10.1016/S1535-6108(03)00169-7
P577
2003-07-01T00:00:00Z