Engineering antigen-specific T cells from genetically modified human hematopoietic stem cells in immunodeficient mice. - Wikidata - wikimedia - TriplyDB

Engineering antigen-specific T cells from genetically modified human hematopoietic stem cells in immunodeficient mice.

Engineering antigen-specific T cells from genetically modified human hematopoietic stem cells in immunodeficient mice.

http://www.wikidata.org/entity/Q30974719

about

In vivo suppression of HIV by antigen specific T cells derived from engineered hematopoietic stem cells Advancing animal models of human type 1 diabetes by engraftment of functional human tissues in immunodeficient mice Gene therapy strategies for HIV/AIDS: preclinical modeling in humanized mice In Vivo Murine-Matured Human CD3+ Cells as a Preclinical Model for T Cell-Based Immunotherapies.Probing the effector and suppressive functions of human T cell subsets using antigen-specific engineered T cell receptors Stem cell-based anti-HIV gene therapy.Antitumor activity from antigen-specific CD8 T cells generated in vivo from genetically engineered human hematopoietic stem cells.Cocaine-mediated impact on HIV infection in humanized BLT mice.BLT humanized mice as a small animal model of HIV infection.Targeted cytotoxic therapy: adapting a rapidly progressing anticancer paradigm for depletion of persistent HIV-infected cell reservoirs.Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID "Meet the Experts" 2015 Workshop Summary.HIV-specific Immunity Derived From Chimeric Antigen Receptor-engineered Stem Cells.Hematopoietic stem cells for cancer immunotherapy Stem cell-based approaches to treating HIV infection.Potential clinical applications for human pluripotent stem cell-derived blood components.Ex vivo gene transfer and correction for cell-based therapies.Curing HIV: lessons from cancer therapy Engineering HIV-Specific Immunity with Chimeric Antigen Receptors.Targeting type I interferon-mediated activation restores immune function in chronic HIV infection.Chimeric antigen receptor engineered stem cells: a novel HIV therapy.Human pluripotent stem cells produce natural killer cells that mediate anti-HIV-1 activity by utilizing diverse cellular mechanisms.Pre-clinical development of gene modification of haematopoietic stem cells with chimeric antigen receptors for cancer immunotherapy.Stem-cell Based Engineered Immunity Against HIV Infection in the Humanized Mouse Model.Engineering hematopoietic stem cells to create melanoma specific CTL.Human immune system development and survival of non-obese diabetic (NOD)-scid IL2rγ(null) (NSG) mice engrafted with human thymus and autologous haematopoietic stem cells.Novel drugs and treatment strategies for HIV-1.The Use of the Humanized Mouse Model in Gene Therapy and Immunotherapy for HIV and Cancer.

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Engineering antigen-specific T cells from genetically modified human hematopoietic stem cells in immunodeficient mice.

http://www.wikidata.org/entity/Q30974719

description

2009 nî lūn-bûn

@nan

2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Engineering antigen-specific T ...... cells in immunodeficient mice.

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Engineering antigen-specific T ...... cells in immunodeficient mice.

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Engineering antigen-specific T ...... cells in immunodeficient mice.

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Engineering antigen-specific T ...... cells in immunodeficient mice.

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JOURNAL.PONE.0008208

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Engineering antigen-specific T ...... cells in immunodeficient mice.

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Alan Young

http://www.w3.org/2001/XMLSchema#string

Alexis Lieberman

http://www.w3.org/2001/XMLSchema#string

Aviva Joseph

http://www.w3.org/2001/XMLSchema#string

Harris Goldstein

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Hwee Ng

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Jerome A Zack

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Joanne Kim

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Michael Bennett

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Otto Yang

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Qing Xu

http://www.w3.org/2001/XMLSchema#string

P2860

Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection

Cancer regression in patients after transfer of genetically engineered lymphocytes

Costimulation of naive CD8(+) lymphocytes induces CD4 expression and allows human immunodeficiency virus type 1 infection.

Transfer of specificity for human immunodeficiency virus type 1 into primary human T lymphocytes by introduction of T-cell receptor genes

Detection of individual mouse splenic T cells producing IFN-gamma and IL-5 using the enzyme-linked immunospot (ELISPOT) assay.

Long-term in vivo provision of antigen-specific T cell immunity by programming hematopoietic stem cells.

The CD4 molecule on CD8+ T lymphocytes directly enhances the immune response to viral and cellular antigens

Generation of functional antigen-specific T cells in defined genetic backgrounds by retrovirus-mediated expression of TCR cDNAs in hematopoietic precursor cells.

Long-term culture and fine specificity of human cytotoxic T-lymphocyte clones reactive with human immunodeficiency virus type 1.

Transfer of a TCR gene derived from a patient with a marked antitumor response conveys highly active T-cell effector functions.

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scholarly article

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10.1371/JOURNAL.PONE.0008208

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