Highly efficient, nonpeptidic oligoguanidinium vectors that selectively internalize into mitochondria.
about
Combinatorial drug design targeting multiple cancer signaling networks controlled by mitochondrial Hsp90Cationic membrane peptides: atomic-level insight of structure-activity relationships from solid-state NMRLysosomotropic properties of weakly basic anticancer agents promote cancer cell selectivity in vitroSynthetic ligands able to interact with the p53 tetramerization domain. Towards understanding a protein surface recognition event.The subcellular distribution of small molecules: a meta-analysis.On guanidinium and cellular uptake.Semitelechelic HPMA copolymers functionalized with triphenylphosphonium as drug carriers for membrane transduction and mitochondrial localization.Controlled Endolysosomal Release of Agents by pH-responsive Polymer Blend ParticlesMolecular recognition of oxoanions based on guanidinium receptors.The design of guanidinium-rich transporters and their internalization mechanisms.Nanovehicular intracellular delivery systems.Compartmentalized cancer drug discovery targeting mitochondrial Hsp90 chaperones.The subcellular distribution of small molecules: from pharmacokinetics to synthetic biologyMitochondrial delivery of doxorubicin by triphenylphosphonium-functionalized hyperbranched nanocarriers results in rapid and severe cytotoxicity.Dendrimer-type peptoid-decorated hexaphenylxylenes and tetraphenylmethanes: synthesis and structure in solution and in the gas phase.Mitochondria-Targeted Triphenylphosphonium-Based Compounds: Syntheses, Mechanisms of Action, and Therapeutic and Diagnostic Applications.Highly efficient intracellular drug delivery with a negatively charged hyperbranched polysulfonamine.Guanidinylated neomycin delivers large, bioactive cargo into cells through a heparan sulfate-dependent pathway.Cellular Antisense Activity of PNA-Oligo(bicycloguanidinium) Conjugates Forming Self-Assembled Nanoaggregates.Triphenylphosphonium Moiety Modulates Proteolytic Stability and Potentiates Neuroprotective Activity of Antioxidant Tetrapeptides in Vitro.A cationic morpholino antisense oligomer conjugate: synthesis, cellular uptake and inhibition of Gli1 in the hedgehog signalling pathwayCell-penetrating poly(disulfide)s: the dependence of activity, depolymerization kinetics and intracellular localization on their lengthCell-penetrating poly(disulfide)s: focus on substrate-initiated co-polymerizationNon-peptidic cell-penetrating agents: synthesis of oligomeric chiral bicyclic guanidinium vectors
P2860
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P2860
Highly efficient, nonpeptidic oligoguanidinium vectors that selectively internalize into mitochondria.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Highly efficient, nonpeptidic ...... internalize into mitochondria.
@ast
Highly efficient, nonpeptidic ...... internalize into mitochondria.
@en
type
label
Highly efficient, nonpeptidic ...... internalize into mitochondria.
@ast
Highly efficient, nonpeptidic ...... internalize into mitochondria.
@en
prefLabel
Highly efficient, nonpeptidic ...... internalize into mitochondria.
@ast
Highly efficient, nonpeptidic ...... internalize into mitochondria.
@en
P2093
P356
P1476
Highly efficient, nonpeptidic ...... internalize into mitochondria.
@en
P2093
Javier de Mendoza
Jimena Fernández-Carneado
Michiel Van Gool
Pilar Prados
Susanna Castel
Vera Martos
P304
P356
10.1021/JA044006Q
P407
P577
2005-01-01T00:00:00Z