The IA-2 gene family: homologs in Caenorhabditis elegans, Drosophila and zebrafish.

The IA-2 gene family: homologs in Caenorhabditis elegans, Drosophila and zebrafish.

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http://www.wikidata.org/entity/Q30981023
The zinc-finger transcription factor INSM1 is expressed during embryo development and interacts with the Cbl-associated protein.Multimerization of the protein-tyrosine phosphatase (PTP)-like insulin-dependent diabetes mellitus autoantigens IA-2 and IA-2beta with receptor PTPs (RPTPs). Inhibition of RPTPalpha enzymatic activityAutoimmune type 1 diabetes: resolved and unresolved issuesDeletion of Ia-2 and/or Ia-2β in mice decreases insulin secretion by reducing the number of dense core vesiclesPatterns of gene expression in the developing adult sea urchin central nervous system reveal multiple domains and deep-seated neural pentamery.Loss of the transcriptional repressor PAG-3/Gfi-1 results in enhanced neurosecretion that is dependent on the dense-core vesicle membrane protein IDA-1/IA-2.The dense core transmembrane vesicle protein IA-2 is a regulator of vesicle number and insulin secretion.Identification and expression of the family of classical protein-tyrosine phosphatases in zebrafish.IA-2beta, but not IA-2, is induced by ghrelin and inhibits glucose-stimulated insulin secretion.The Jerusalem Perinatal Study cohort, 1964-2005: methods and a review of the main resultsIda-1, the Caenorhabditis elegans orthologue of mammalian diabetes autoantigen IA-2, potentially acts as a common modulator between Parkinson's disease and Diabetes: role of Daf-2/Daf-16 insulin like signalling pathwayGene silencing of phogrin unveils its essential role in glucose-responsive pancreatic beta-cell growthSex, diabetes and the kidney.Pathophysiologic changes in IA-2/IA-2β null mice are secondary to alterations in the secretion of hormones and neurotransmitters.Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster.Dense core vesicle dynamics in Caenorhabditis elegans neurons and the role of kinesin UNC-104.Overexpression of the autoantigen IA-2 puts beta cells into a pre-apoptotic state: autoantigen-induced, but non-autoimmune-mediated, tissue destruction.
P2860

The IA-2 gene family: homologs in Caenorhabditis elegans, Drosophila and zebrafish.

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http://www.wikidata.org/entity/Q30981023
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2001 nî lūn-bûn
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2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2001年の論文
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2001年論文
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2001年論文
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2001年論文
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2001年論文
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2001年论文
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The IA-2 gene family: homologs in Caenorhabditis elegans, Drosophila and zebrafish.
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The IA-2 gene family: homologs in Caenorhabditis elegans, Drosophila and zebrafish.
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type
label
The IA-2 gene family: homologs in Caenorhabditis elegans, Drosophila and zebrafish.
@ast
The IA-2 gene family: homologs in Caenorhabditis elegans, Drosophila and zebrafish.
@en
prefLabel
The IA-2 gene family: homologs in Caenorhabditis elegans, Drosophila and zebrafish.
@ast
The IA-2 gene family: homologs in Caenorhabditis elegans, Drosophila and zebrafish.
@en
P1433
P1476
P2093
P2888
P304
P31
P356
P433
P478
P577
P5875
P6179
P698
P921
P356
P1433
P1476
The IA-2 gene family: homologs in Caenorhabditis elegans, Drosophila and zebrafish.
@en
P2093
P2888
P304
P31
P356
P433
P478
P577
P5875
P6179
P698
P921