Parathyroid hormone-related peptide stimulates osteogenic cell proliferation through protein kinase C activation of the Ras/mitogen-activated protein kinase signaling pathway.
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Parathyroid hormone is essential for normal fetal bone formationThe TIP39-PTH2 receptor system: unique peptidergic cell groups in the brainstem and their interactions with central regulatory mechanisms.Phospholipase C signaling via the parathyroid hormone (PTH)/PTH-related peptide receptor is essential for normal bone responses to PTH.Discoveries, drugs and skeletal disorders.Regulation of Erk1/2 activation by osteopontin in PC3 human prostate cancer cellsTreatment with N- and C-terminal peptides of parathyroid hormone-related protein partly compensate the skeletal abnormalities in IGF-I deficient mice.Recombinant human parathyroid hormone related protein 1-34 and 1-84 and their roles in osteoporosis treatment.The calcium-sensing receptor mediates bone turnover induced by dietary calcium and parathyroid hormone in neonates.Contributions of parathyroid hormone (PTH)/PTH-related peptide receptor signaling pathways to the anabolic effect of PTH on boneMolecular and cellular mechanisms of the anabolic effect of intermittent PTHDisruption of parathyroid hormone and parathyroid hormone-related peptide receptor phosphorylation prolongs ERK1/2 MAPK activation and enhances c-fos expressionEmerging and potential therapies for osteoporosis.Osteoblastic activation in the hematopoietic stem cell niche.The parathyroid hormone-related protein receptor is expressed in breast cancer bone metastases and promotes autocrine proliferation in breast carcinoma cellsRole of Regulators of G Protein Signaling Proteins in Bone Physiology and Pathophysiology.Emerging pharmacologic therapies for osteoporosis.Intermittent parathyroid hormone (1-34) application regulates cAMP-response element binding protein activity to promote the proliferation and osteogenic differentiation of bone mesenchymal stromal cells, via the cAMP/PKA signaling pathway.Differentiation and proliferation of periosteal osteoblast progenitors are differentially regulated by estrogens and intermittent parathyroid hormone administrationRole of regulator of G protein signaling proteins in bone.Osteogenic Differentiation of Periosteal Cells During Fracture Healing.Heterotrimeric G proteins in the control of parathyroid hormone actions.PTHrP promotes colon cancer cell migration and invasion in an integrin α6β4-dependent manner through activation of Rac1.Antiproliferative and survival properties of PMA in MCF-7 breast cancer cell.Proline-rich motifs in the parathyroid hormone (PTH)/PTH-related protein receptor C terminus mediate scaffolding of c-Src with beta-arrestin2 for ERK1/2 activation.Up-regulation of per mRNA expression by parathyroid hormone through a protein kinase A-CREB-dependent mechanism in chondrocytes.Impact of the mitogen-activated protein kinase pathway on parathyroid hormone-related protein actions in osteoblasts.Parathyroid hormone induction of the osteocalcin gene. Requirement for an osteoblast-specific element 1 sequence in the promoter and involvement of multiple-signaling pathways.Continuous and intermittent exposure of neonatal rat calvarial cells to PTHrP (1-36) inhibits bone nodule mineralization in vitro by downregulating bone sialoprotein expression via the cAMP signaling pathway.Parathyroid Hormone Activates Phospholipase C (PLC)-Independent Protein Kinase C Signaling Pathway via Protein Kinase A (PKA)-Dependent Mechanism: A New Defined Signaling Route Would Induce Alternative Consideration to Previous Conceptions.Platelet-released supernatants increase migration and proliferation, and decrease osteogenic differentiation of bone marrow-derived mesenchymal progenitor cells under in vitro conditions.Type 1 receptor parathyroid hormone (PTH1R) influences breast cancer cell proliferation and apoptosis induced by high levels of glucose.
P2860
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P2860
Parathyroid hormone-related peptide stimulates osteogenic cell proliferation through protein kinase C activation of the Ras/mitogen-activated protein kinase signaling pathway.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Parathyroid hormone-related pe ...... tein kinase signaling pathway.
@ast
Parathyroid hormone-related pe ...... tein kinase signaling pathway.
@en
type
label
Parathyroid hormone-related pe ...... tein kinase signaling pathway.
@ast
Parathyroid hormone-related pe ...... tein kinase signaling pathway.
@en
prefLabel
Parathyroid hormone-related pe ...... tein kinase signaling pathway.
@ast
Parathyroid hormone-related pe ...... tein kinase signaling pathway.
@en
P2093
P2860
P356
P1476
Parathyroid hormone-related pe ...... tein kinase signaling pathway.
@en
P2093
P2860
P304
32204-32213
P356
10.1074/JBC.M101084200
P407
P577
2001-06-11T00:00:00Z