Angiotensin-converting enzyme degrades Alzheimer amyloid beta-peptide (A beta ); retards A beta aggregation, deposition, fibril formation; and inhibits cytotoxicity.
about
Transthyretin and the brain re-visited: is neuronal synthesis of transthyretin protective in Alzheimer's disease?beta-Amyloid degradation and Alzheimer's diseaseA modern understanding of the traditional and nontraditional biological functions of angiotensin-converting enzymeAbeta42-to-Abeta40- and angiotensin-converting activities in different domains of angiotensin-converting enzymeAssessment of Alzheimer's disease case-control associations using family-based methodsMechanisms of Aβ Clearance and Degradation by Glial CellsCerebrovascular disease in ageing and Alzheimer's diseaseEndothelin-converting enzymes and related metalloproteases in Alzheimer's diseaseThe genetics of Alzheimer diseaseAlzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzymeβ-Amyloid1-42, HIV-1Ba-L (clade B) infection and drugs of abuse induced degeneration in human neuronal cells and protective effects of ashwagandha (Withania somnifera) and its constituent Withanolide ALidocaine attenuates cognitive impairment after isoflurane anesthesia in old rats.Puromycin-sensitive aminopeptidase is the major peptidase responsible for digesting polyglutamine sequences released by proteasomes during protein degradationConfronting complexity in late-onset Alzheimer disease: application of two-stage analysis approach addressing heterogeneity and epistasisFocusing the amyloid cascade hypothesis on N-truncated Abeta peptides as drug targets against Alzheimer's diseaseDegradation of soluble and fibrillar amyloid beta-protein by matrix metalloproteinase (MT1-MMP) in vitroAn association analysis of Alzheimer disease candidate genes detects an ancestral risk haplotype clade in ACE and putative multilocus association between ACE, A2M, and LRRTM3.The association of angiotensin-converting enzyme with biomarkers for Alzheimer's diseaseMultiple insulin degrading enzyme variants alter in vitro reporter gene expressionProteases and proteolysis in Alzheimer disease: a multifactorial view on the disease process.GLP-1 receptor stimulation reduces amyloid-beta peptide accumulation and cytotoxicity in cellular and animal models of Alzheimer's disease.ACE variants and association with brain Aβ levels in Alzheimer's diseaseExploratory data from complete genomes of familial alzheimer disease age-at-onset outliers.Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammationAmyloid beta-protein is degraded by cellular angiotensin-converting enzyme (ACE) and elevated by an ACE inhibitor.Ameliorative effects of a combination of baicalin, jasminoidin and cholic acid on ibotenic acid-induced dementia model in rats.No association between DCP1 genotype and late-onset Alzheimer disease.Ginsenoside Rg1 decreases Aβ(1-42) level by upregulating PPARγ and IDE expression in the hippocampus of a rat model of Alzheimer's disease.Association of polymorphisms in the Angiotensin-converting enzyme gene with Alzheimer disease in an Israeli Arab communityAshwagandha (Withania somnifera) reverses β-amyloid1-42 induced toxicity in human neuronal cells: implications in HIV-associated neurocognitive disorders (HAND).Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein.The renin-angiotensin-aldosterone system and Alzheimer s disease?Hypertension and cognitive functionInfluence of Coding Variability in APP-Aβ Metabolism Genes in Sporadic Alzheimer's Disease.Interactions between oestrogen and the renin angiotensin system - potential mechanisms for gender differences in Alzheimer's disease.Exploring the contribution of estrogen to amyloid-Beta regulation: a novel multifactorial computational modeling approach.Impact of Angiotensin receptor blockers on Alzheimer disease neuropathology in a large brain autopsy series.Lack of association between angiotensin-converting enzyme and dementia of the Alzheimer's type in an elderly Arab population in Wadi Ara, IsraelThe Role of the Renin-Angiotensin System in Amyloid Metabolism of Alzheimer's DiseaseAmyloid-beta protein clearance and degradation (ABCD) pathways and their role in Alzheimer's disease.
P2860
Q21202832-4928ED53-A523-413B-B7BF-BA9CF93ECA2EQ21284467-43FBA4C2-4629-4DA1-8DFC-A456A6613280Q24306614-8BF122D4-E17B-4A55-B0B1-D45F66309D5FQ24317730-8CA90883-B22B-4E09-8D07-ADDCF334413DQ24622654-C5F06902-8081-4B17-B1C7-83CD54F9B68EQ26741609-B431ACB2-8845-44A6-98D5-2193F536D101Q26771852-DDAEF0A0-F8C5-4290-9CF5-9128E0CBABE7Q26862901-B7C35E60-A9F3-4EE0-88FA-FB0B31734E5EQ27026166-AE0E70C4-DEE2-4DC0-8B54-6EBD307BB066Q28216644-07F1AD12-5467-4A35-AD6D-BFB8598566A8Q28545117-E47F7252-E63D-48EB-BEFB-75C6E0894560Q30421873-F362F620-C276-46BA-9D4D-4F2886F3CE09Q33275164-6DE84B7A-41ED-4F72-8781-E20D153CA7ECQ33583920-A8E2B1F1-AB66-4838-AF98-1BF61C831EC5Q33624303-93A52926-711A-407E-8657-235E1DE2FAF6Q33643056-E81211F0-9A0D-4342-908B-CF16792B0883Q33652202-716AB762-114B-4C35-91B8-DB0653A18495Q33821846-886EF562-2E08-4925-A25D-F9EE1533FC28Q33952436-DCB75868-66AA-4923-B5F0-F89D9754DBBCQ34110227-AE311BAC-59FD-42E1-B219-508535CC5429Q34167980-941B2A19-D8D4-4E15-9CAC-4089F61FF2BDQ34310258-63C7742D-F57F-41C1-86F7-DDB04CAAB319Q34350733-BF4E266E-29C7-4986-9CEF-11580B251262Q34394932-1F93F2F3-BAF1-43DC-A0B4-CE7DADECE559Q34449990-36D691AA-B2CC-45B3-9FA4-94AE15349C57Q34599205-B8A6A2AF-1CB8-40AA-954C-790D0C08443FQ34626057-DB529CAE-8B7D-4305-B8D5-EA1114E46427Q34632017-A8C86282-9BAD-42A2-B3FA-E46882E3C0C9Q34658026-2C3EA352-A8B8-4D1F-B359-D6D2EA04B0E7Q35023273-ABF504E5-9FC1-408A-915F-839A5BBECCC1Q35097358-D8BD4051-A306-4942-B4B1-AA0F46550325Q35154546-7337059E-5831-4421-91F9-7C1C9E9EBF9EQ35178724-9371C353-73F9-477F-B565-ECDAE5B465FBQ36036376-75DE11B6-CF9D-427C-9261-3878E06C8745Q36576477-8E701FF3-F178-478A-9180-A4DE085BCFADQ36648823-8C9FB2A6-BBD3-4693-92C5-87E223B87933Q36716390-1506C07F-E547-43DD-BB23-D5885DB2AC0EQ36718037-914959FE-4CCD-4172-82CF-C9254E2DEB97Q36721915-FE4FE8FF-931B-4987-B367-B8AF66A92484Q36764094-D76A813F-310F-4F05-B779-7D7FAC39E171
P2860
Angiotensin-converting enzyme degrades Alzheimer amyloid beta-peptide (A beta ); retards A beta aggregation, deposition, fibril formation; and inhibits cytotoxicity.
description
2001 nî lūn-bûn
@nan
2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Angiotensin-converting enzyme ...... on; and inhibits cytotoxicity.
@ast
Angiotensin-converting enzyme ...... on; and inhibits cytotoxicity.
@en
type
label
Angiotensin-converting enzyme ...... on; and inhibits cytotoxicity.
@ast
Angiotensin-converting enzyme ...... on; and inhibits cytotoxicity.
@en
prefLabel
Angiotensin-converting enzyme ...... on; and inhibits cytotoxicity.
@ast
Angiotensin-converting enzyme ...... on; and inhibits cytotoxicity.
@en
P2093
P356
P1476
Angiotensin-converting enzyme ...... on; and inhibits cytotoxicity.
@en
P2093
P304
47863-47868
P356
10.1074/JBC.M104068200
P407
P577
2001-10-16T00:00:00Z