Identification of potent and selective mechanism-based inhibitors of the cysteine protease cruzain using solid-phase parallel synthesis.

Identification of potent and selective mechanism-based inhibitors of the cysteine protease cruzain using solid-phase parallel synthesis.

Item
http://www.wikidata.org/entity/Q31036035
Peptide-bond modification for metal coordination: peptides containing two hydroxamate groups.Risedronate metal complexes potentially active against Chagas disease.Novel cruzain inhibitors for the treatment of Chagas' disease.Chemical-biological characterization of a cruzain inhibitor reveals a second target and a mammalian off-target.Use of cysteine-reactive small molecules in drug discovery for trypanosomal disease.Design, Synthesis, and Biological Evaluation of Peptidomimetic N-Substituted Cbz-4-Hyp-Hpa-Amides as Novel Inhibitors of Plasmodium falciparum.Synthesis, 2D-NMR and molecular modelling studies of pentacycloundecane lactam-peptides and peptoids as potential HIV-1 wild type C-SA protease inhibitors.2-(3,4-dihydro-4-oxothieno[2,3-d]pyrimidin-2-ylthio) acetamides as a new class of falcipain-2 inhibitors. 3. design, synthesis and biological evaluation.2-amido-3-(1H-indol-3-yl)-N-substituted-propanamides as a new class of falcipain-2 inhibitors. 1. Design, synthesis, biological evaluation and binding model studies.Cysteine protease inhibitors as potential antiparasitic agents
P2860

Identification of potent and selective mechanism-based inhibitors of the cysteine protease cruzain using solid-phase parallel synthesis.

Item
http://www.wikidata.org/entity/Q31036035
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Identification of potent and s ...... olid-phase parallel synthesis.
@ast
Identification of potent and s ...... olid-phase parallel synthesis.
@en
type
label
Identification of potent and s ...... olid-phase parallel synthesis.
@ast
Identification of potent and s ...... olid-phase parallel synthesis.
@en
prefLabel
Identification of potent and s ...... olid-phase parallel synthesis.
@ast
Identification of potent and s ...... olid-phase parallel synthesis.
@en
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P356
P1433
P1476
Identification of potent and s ...... olid-phase parallel synthesis.
@en
P2093
P304
P31
P356
P407
P433
P478
P577
P698