Rapid identification of high affinity peptide ligands using positional scanning synthetic peptide combinatorial libraries.
about
pCAP-based peptide substrates: the new tool in the box of tyrosine phosphatase assaysShifting from the single to the multitarget paradigm in drug discoveryA Single T Cell Receptor Bound to Major Histocompatibility Complex Class I and Class II Glycoproteins Reveals Switchable TCR ConformersMixture-based heterocyclic combinatorial positional scanning libraries: discovery of bicyclic guanidines having potent antifungal activities against Candida albicans and Cryptococcus neoformansMetal-specific CD4+ T-cell responses induced by beryllium exposure in HLA-DP2 transgenic miceIdentification of Protein Palmitoylation Inhibitors from a Scaffold Ranking LibraryPeptide-binding motifs of two common equine class I MHC molecules in Thoroughbred horsesThe common equine class I molecule Eqca-1*00101 (ELA-A3.1) is characterized by narrow peptide binding and T cell epitope repertoires.Identification of novel hexapeptides bioactive against phytopathogenic fungi through screening of a synthetic peptide combinatorial libraryKinase peptide specificity: improved determination and relevance to protein phosphorylationA synthetic combinatorial strategy for developing alpha-conotoxin analogs as potent alpha7 nicotinic acetylcholine receptor antagonists.Derivation of an amino acid similarity matrix for peptide: MHC binding and its application as a Bayesian prior.Surface-active fungicidal D-peptide inhibitors of the plasma membrane proton pump that block azole resistance.Combinatorial peptide libraries: mining for cell-binding peptides.In vitro and direct in vivo testing of mixture-based combinatorial libraries for the identification of highly active and specific opiate ligands.Cerebrospinal fluid-infiltrating CD4+ T cells recognize Borrelia burgdorferi lysine-enriched protein domains and central nervous system autoantigens in early lyme encephalitisQuantitative peptide binding motifs for 19 human and mouse MHC class I molecules derived using positional scanning combinatorial peptide libraries.Using specificity to strategically target proteases.Two MHC class I molecules associated with elite control of immunodeficiency virus replication, Mamu-B*08 and HLA-B*2705, bind peptides with sequence similarity.The specificity of the transforming growth factor beta receptor kinases determined by a spatially addressable peptide libraryPeptide binding predictions for HLA DR, DP and DQ moleculesA high-content screening (HCS) assay for the identification of chemical inducers of PML oncogenic domains (PODs).The role of MHC class I allele Mamu-A*07 during SIV(mac)239 infectionInhibitor screening of proprotein convertases using positional scanning libraries.Library of libraries: approach to synthetic combinatorial library design and screening of "pharmacophore" motifs.Identification of beryllium-dependent peptides recognized by CD4+ T cells in chronic beryllium diseaseHTS by NMR of combinatorial libraries: a fragment-based approach to ligand discovery.The mathematics of a successful deconvolution: a quantitative assessment of mixture-based combinatorial libraries screened against two formylpeptide receptorsSelective agonists and antagonists of formylpeptide receptors: duplex flow cytometry and mixture-based positional scanning libraries.Creation and functional screening of a multi-use peptide library.Identification of tetrapeptides from a mixture based positional scanning library that can restore nM full agonist function of the L106P, I69T, I102S, A219V, C271Y, and C271R human melanocortin-4 polymorphic receptors (hMC4Rs).High-Throughput Screening by Nuclear Magnetic Resonance (HTS by NMR) for the Identification of PPIs AntagonistsHigh-Throughput Screening (HTS) by NMR Guided Identification of Novel Agents Targeting the Protein Docking Domain of YopH.Direct Phenotypic Screening in Mice: Identification of Individual, Novel Antinociceptive Compounds from a Library of 734,821 Pyrrolidine Bis-piperazines.Tagged versus untagged libraries: methods for the generation and screening of combinatorial chemical libraries."Libraries from libraries": chemical transformation of combinatorial libraries to extend the range and repertoire of chemical diversity.Small-Molecule Inhibitors Targeting Topoisomerase I as Novel Antituberculosis Agents.Myelin basic protein-specific TCR/HLA-DRB5*01:01 transgenic mice support the etiologic role of DRB5*01:01 in multiple sclerosis.Discovery of Mixed Pharmacology Melanocortin-3 Agonists and Melanocortin-4 Receptor Tetrapeptide Antagonist Compounds (TACOs) Based on the Sequence Ac-Xaa1-Arg-(pI)DPhe-Xaa4-NH2.Identification of high potency microbial and self ligands for a human autoreactive class II-restricted T cell clone.
P2860
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P2860
Rapid identification of high affinity peptide ligands using positional scanning synthetic peptide combinatorial libraries.
description
1992 nî lūn-bûn
@nan
1992 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Rapid identification of high a ...... ptide combinatorial libraries.
@ast
Rapid identification of high a ...... ptide combinatorial libraries.
@en
type
label
Rapid identification of high a ...... ptide combinatorial libraries.
@ast
Rapid identification of high a ...... ptide combinatorial libraries.
@en
prefLabel
Rapid identification of high a ...... ptide combinatorial libraries.
@ast
Rapid identification of high a ...... ptide combinatorial libraries.
@en
P2093
P1433
P1476
Rapid identification of high a ...... ptide combinatorial libraries.
@en
P2093
P304
P577
1992-12-01T00:00:00Z