Small-molecule targeting of proliferating cell nuclear antigen chromatin association inhibits tumor cell growth.
about
The Mcm2-7 replicative helicase: a promising chemotherapeutic targetA novel mechanism for regulating the activity of proliferating cell nuclear antigen by a small proteinTargeting proliferating cell nuclear antigen and its protein interactions induces apoptosis in multiple myeloma cells.A Peptide mimicking a region in proliferating cell nuclear antigen specific to key protein interactions is cytotoxic to breast cancer.Mitochondrial ferritin, a new target for inhibiting neuronal tumor cell proliferation.A PCNA-derived cell permeable peptide selectively inhibits neuroblastoma cell growth.STAT1 modification improves therapeutic effects of interferons on lung cancer cellsPrognostic value and clinicopathological significance of proliferating cell nuclear antigen expression in gastric cancer: a systematic review and meta-analysisAldose reductase inhibition suppresses azoxymethane-induced colonic premalignant lesions in C57BL/KsJ-db/db mice.Retinoic acid inhibits the cytoproliferative response to weak 50‑Hz magnetic fields in neuroblastoma cells.Overexpression of PCNA Attenuates Oxidative Stress-Caused Delay of Gap-Filling during Repair of UV-Induced DNA DamageReview: The lord of the rings: Structure and mechanism of the sliding clamp loader.Replication factor C3 is a CREB target gene that regulates cell cycle progression through the modulation of chromatin loading of PCNA.Target validation and structure-activity analysis of a series of novel PCNA inhibitorsForging Ahead through Darkness: PCNA, Still the Principal Conductor at the Replication Fork.A small molecule inhibitor of monoubiquitinated Proliferating Cell Nuclear Antigen (PCNA) inhibits repair of interstrand DNA cross-link, enhances DNA double strand break, and sensitizes cancer cells to cisplatin.Deviating the level of proliferating cell nuclear antigen in Trypanosoma brucei elicits distinct mechanisms for inhibiting proliferation and cell cycle progression.Inhibition of DNA replication by an anti-PCNA aptamer/PCNA complex.The dark side of the ring: role of the DNA sliding surface of PCNA.Structure-Guided Synthesis and Mechanistic Studies Reveal Sweetspots on Naphthyl Salicyl Hydrazone Scaffold as Non-Nucleosidic Competitive, Reversible Inhibitors of Human Ribonucleotide Reductase.Potent competitive inhibition of human ribonucleotide reductase by a nonnucleoside small molecule.The Human Replicative Helicase, the CMG Complex, as a Target for Anti-cancer Therapy.Aldose reductase inhibitor, fidarestat prevents high-fat diet-induced intestinal polyps in ApcMin/+ mice.Proteomic Investigation to Identify Anticancer Targets of Nemopilema nomurai Jellyfish Venom in Human Hepatocarcinoma HepG2 Cells.DNA Sliding Clamps as Therapeutic TargetsA combination of curcumin and oligomeric proanthocyanidins offer superior anti-tumorigenic properties in colorectal cancer
P2860
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P2860
Small-molecule targeting of proliferating cell nuclear antigen chromatin association inhibits tumor cell growth.
description
2012 nî lūn-bûn
@nan
2012 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մարտին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Small-molecule targeting of pr ...... on inhibits tumor cell growth.
@ast
Small-molecule targeting of pr ...... on inhibits tumor cell growth.
@en
type
label
Small-molecule targeting of pr ...... on inhibits tumor cell growth.
@ast
Small-molecule targeting of pr ...... on inhibits tumor cell growth.
@en
prefLabel
Small-molecule targeting of pr ...... on inhibits tumor cell growth.
@ast
Small-molecule targeting of pr ...... on inhibits tumor cell growth.
@en
P2093
P2860
P356
P1476
Small-molecule targeting of pr ...... on inhibits tumor cell growth.
@en
P2093
Chris R Evelyn
Kelsey L Dillehay
Linda H Malkas
Matthew Wortman
Shanna J Smith
William L Seibel
Zhongyun Dong
Zongqing Tan
P2860
P304
P356
10.1124/MOL.112.077735
P577
2012-03-07T00:00:00Z