The XPC-HR23B complex displays high affinity and specificity for damaged DNA in a true-equilibrium fluorescence assay.
about
Defining the function of xeroderma pigmentosum group F protein in psoralen interstrand cross-link-mediated DNA repair and mutagenesisHuman XPC-hHR23B interacts with XPA-RPA in the recognition of triplex-directed psoralen DNA interstrand crosslinks.Determination of protein-DNA binding constants and specificities from statistical analyses of single molecules: MutS-DNA interactionsGlobal-genome Nucleotide Excision Repair Controlled by Ubiquitin/Sumo ModifiersXeroderma pigmentosum group C sensor: unprecedented recognition strategy and tight spatiotemporal regulationBinding of the human nucleotide excision repair proteins XPA and XPC/HR23B to the 5R-thymine glycol lesion and structure of the cis-(5R,6S) thymine glycol epimer in the 5'-GTgG-3' sequence: destabilization of two base pairs at the lesion siteStructure of (5′ S )-8,5′-Cyclo-2′-deoxyguanosine in DNATwist-open mechanism of DNA damage recognition by the Rad4/XPC nucleotide excision repair complexXPC: Going where no DNA damage sensor has gone beforeBiochemical analysis of the damage recognition process in nucleotide excision repair.Xeroderma pigmentosum complementation group E protein (XPE/DDB2): purification of various complexes of XPE and analyses of their damaged DNA binding and putative DNA repair properties.Biochemical and structural domain analysis of xeroderma pigmentosum complementation group C protein.An aromatic sensor with aversion to damaged strands confers versatility to DNA repairA mathematical model for human nucleotide excision repair: damage recognition by random order assembly and kinetic proofreading.The role of Bcl-x(L) protein in nucleotide excision repair-facilitated cell protection against cisplatin-induced apoptosis.Rad23 stabilizes Rad4 from degradation by the Ub/proteasome pathwayThe relationships between XPC binding to conformationally diverse DNA adducts and their excision by the human NER system: is there a correlation?Nucleotide Excision Repair Lesion-Recognition Protein Rad4 Captures a Pre-Flipped Partner Base in a Benzo[a]pyrene-Derived DNA Lesion: How Structure Impacts the Binding PathwayStochastic and reversible assembly of a multiprotein DNA repair complex ensures accurate target site recognition and efficient repair.Effect of the multifunctional proteins RPA, YB-1, and XPC repair factor on AP site cleavage by DNA glycosylase NEIL1.In vivo recruitment of XPC to UV-induced cyclobutane pyrimidine dimers by the DDB2 gene product.Polymorphisms in XPC provide prognostic information in acute myeloid leukemia.Kinetic gating mechanism of DNA damage recognition by Rad4/XPCStructural insights into the recognition of cisplatin and AAF-dG lesion by Rad14 (XPA)Faster DNA Repair of Ultraviolet-Induced Cyclobutane Pyrimidine Dimers and Lower Sensitivity to Apoptosis in Human Corneal Epithelial Cells than in Epidermal Keratinocytes.Molecular mechanisms of xeroderma pigmentosum (XP) proteins.The efficiencies of damage recognition and excision correlate with duplex destabilization induced by acetylaminofluorene adducts in human nucleotide excision repair.Pre-steady-state binding of damaged DNA by XPC-hHR23B reveals a kinetic mechanism for damage discrimination.New synthetic substrates of mammalian nucleotide excision repair systemEukaryotic nucleotide excision repair: from understanding mechanisms to influencing biology.Xeroderma pigmentosum complementation group C protein (XPC) serves as a general sensor of damaged DNA.Xeroderma pigmentosum group C protein interacts with histones: regulation by acetylated states of histone H3.Comparative analysis of interaction of human and yeast DNA damage recognition complexes with damaged DNA in nucleotide excision repair.Local action of the chromatin assembly factor CAF-1 at sites of nucleotide excision repair in vivo.Repair-Resistant DNA Lesions.Single-Molecule Imaging Reveals that Rad4 Employs a Dynamic DNA Damage Recognition ProcessStructure of the XPC binding domain of hHR23A reveals hydrophobic patches for protein interaction.Clinicopathological significance and prognostic value of Xeroderma pigmentosum complementary group C (XPC) expression in sporadic breast cancer patients.Human and yeast DNA damage recognition complexes bind with high affinity DNA structures mimicking in size transcription bubble.Enhanced spontaneous DNA twisting/bending fluctuations unveiled by fluorescence lifetime distributions promote mismatch recognition by the Rad4 nucleotide excision repair complex.
P2860
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P2860
The XPC-HR23B complex displays high affinity and specificity for damaged DNA in a true-equilibrium fluorescence assay.
description
2002 nî lūn-bûn
@nan
2002 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The XPC-HR23B complex displays ...... quilibrium fluorescence assay.
@ast
The XPC-HR23B complex displays ...... quilibrium fluorescence assay.
@en
type
label
The XPC-HR23B complex displays ...... quilibrium fluorescence assay.
@ast
The XPC-HR23B complex displays ...... quilibrium fluorescence assay.
@en
prefLabel
The XPC-HR23B complex displays ...... quilibrium fluorescence assay.
@ast
The XPC-HR23B complex displays ...... quilibrium fluorescence assay.
@en
P2093
P356
P1433
P1476
The XPC-HR23B complex displays ...... quilibrium fluorescence assay.
@en
P2093
Fumio Hanaoka
Georg Lipps
Gerhard Krauss
Kaoru Sugasawa
Shigenori Iwai
Thomas Hey
P304
P356
10.1021/BI012202T
P407
P577
2002-05-01T00:00:00Z