Highly conserved and disease-specific patterns of carboxyterminally truncated Abeta peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation.
about
Biological markers of amyloid beta-related mechanisms in Alzheimer's diseaseTransient dynamics of Aβ contribute to toxicity in Alzheimer's diseaseA window into the heterogeneity of human cerebrospinal fluid Aβ peptidesAlzheimer's disease--a panorama glimpseSystematic Aβ Analysis in Drosophila Reveals High Toxicity for the 1-42, 3-42 and 11-42 Peptides, and Emphasizes N- and C-Terminal ResiduesPresenilin-1, nicastrin, amyloid precursor protein, and gamma-secretase activity are co-localized in the lysosomal membraneAmyloid-beta isoform metabolism quantitation by stable isotope-labeled kineticsCerebrospinal fluid profile of amyloid beta peptides in patients with Alzheimer's disease determined by protein biochip technology.Update on the core and developing cerebrospinal fluid biomarkers for Alzheimer disease.CSF biomarkers for mild cognitive impairment.Characterization of amyloid beta peptides from brain extracts of transgenic mice overexpressing the London mutant of human amyloid precursor protein.Cerebrospinal fluid neurochemical phenotypes in vascular dementias: original data and mini-review.The amyloid-beta (Abeta) peptide pattern in cerebrospinal fluid in Alzheimer's disease: evidence of a novel carboxyterminally elongated Abeta peptide.Consensus paper of the WFSBP Task Force on Biological Markers of Dementia: the role of CSF and blood analysis in the early and differential diagnosis of dementia.CSF amyloid-beta-peptides in Alzheimer's disease, dementia with Lewy bodies and Parkinson's disease dementiaSelective modulation of amyloid-beta peptide degradation by flurbiprofen, fenofibrate, and related compounds regulates Abeta levels.Cerebrospinal fluid biomarkers of Alzheimer's disease.A novel Abeta isoform pattern in CSF reflects gamma-secretase inhibition in Alzheimer diseaseCyclohexanehexol inhibitors of Abeta aggregation prevent and reverse Alzheimer phenotype in a mouse model.The disintegrin/metalloproteinase ADAM10 is essential for the establishment of the brain cortexDirect antigen detection from immunoprecipitated beads using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry; a new method for immunobeads-mass spectrometry (iMS).Confounding factors influencing amyloid Beta concentration in cerebrospinal fluidCombined Analysis of CSF Tau, Aβ42, Aβ1-42% and Aβ1-40% in Alzheimer's Disease, Dementia with Lewy Bodies and Parkinson's Disease Dementia.Phagocytosis and LPS alter the maturation state of β-amyloid precursor protein and induce different Aβ peptide release signatures in human mononuclear phagocytes.Modulation of γ-secretase activity by multiple enzyme-substrate interactions: implications in pathogenesis of Alzheimer's diseaseCharacterization of cerebrospinal fluid aminoterminally truncated and oxidized amyloid-β peptides.Development of a magnetic immunosorbent for on-chip preconcentration of amyloid β isoforms: Representatives of Alzheimer's disease biomarkersStructural study of metastable amyloidogenic protein oligomers by photo-induced cross-linking of unmodified proteinsThe proton-pump inhibitor lansoprazole enhances amyloid beta production.beta-site amyloid precursor protein cleaving enzyme 1 increases amyloid deposition in brain parenchyma but reduces cerebrovascular amyloid angiopathy in aging BACE x APP[V717I] double-transgenic miceCSF beta-amyloid 1-42 - what are we measuring in Alzheimer's disease?CSF tau and β-amyloid as biomarkers for mild cognitive impairment.Beta-amyloid peptide variants in brains and cerebrospinal fluid from amyloid precursor protein (APP) transgenic mice: comparison with human Alzheimer amyloid.Magneto-immunocapture with on-bead fluorescent labeling of amyloid-β peptides: towards a microfluidized-bed-based operation.Microglial Amyloid-β1-40 Phagocytosis Dysfunction Is Caused by High-Mobility Group Box Protein-1: Implications for the Pathological Progression of Alzheimer's Disease.The mechanism of γ-Secretase dysfunction in familial Alzheimer disease.Cerebrospinal fluid protein biomarkers for Alzheimer's disease.An integrated microfluidic chip for immunocapture, preconcentration and separation of β-amyloid peptides.CSF proteome: a protein repository for potential biomarker identification.CSF biomarkers for Alzheimer's disease: use in early diagnosis and evaluation of drug treatment.
P2860
Q24622136-48F56B23-BAFF-4683-AE07-9CB8E2836DAAQ26827421-8812E4E0-09CB-4A14-9CC3-873C4B5135BDQ27010785-02B7A764-427A-4401-938E-3B17CB347246Q27011749-BB898D91-CA5C-4618-9CD8-2E2F35B0D7D5Q28546774-7CC00522-5C92-40D8-92A4-575FBC3513C0Q28568133-8712C582-D5DB-4E09-9083-47A6A3106DB3Q28681651-5480A83B-5158-4A9D-B7A4-78F7DCCECB88Q30822398-7DABBE63-BEB6-4751-9ADB-30C80AFA9263Q30845482-76DF74C9-0F5D-4BC3-BE3A-13BA416131F1Q30953185-26BD870A-B60F-4C3A-9E3B-C92AD253E5BEQ31128115-351F2C46-8724-475E-AFD5-5873AC53FE3DQ31146512-9FB40992-B2B3-409C-A9EF-16B4886CC4E1Q33187435-4322FF79-650F-4FCF-9391-032291BE2051Q33223171-9C907263-BB34-402D-AEFE-341D5DF65121Q33239180-211864CF-94F9-4708-A2BA-4BD1B1769AA8Q33496258-4F6CC479-3601-4632-A970-3A11F320398AQ33757828-A4277464-0026-4295-A908-1992C17E6C6AQ33877903-CA25BB79-7C88-42E3-BABB-5831240C0715Q33996719-F39A47F7-74DD-455A-B2F6-83FE987CED4EQ34067209-DC7BD900-F13D-4214-A4FB-627C561A43E4Q34077448-BEA98B9E-F258-4360-9A32-1F080B82C10BQ34078408-E87557C1-2228-494F-87E1-269B1E5E7C0FQ34123736-41E74ECD-95AC-4637-8293-DB94516839E9Q34220873-FF1C509D-CC96-400A-800A-3C6C77F5A8B0Q34221138-3E6E2E7B-6B3D-4EA9-9AB1-EE3CE779065BQ34244772-21A410EA-39F1-4BF5-91D7-7CF50E39CF95Q34308649-7F6384D6-3AA1-40C7-B9BE-DF0353801505Q34574518-76CB0B2B-11B7-4D90-A126-F53F319D38C7Q34631939-35687317-61CC-4231-B16A-91E11833378DQ35103410-8A4E82C4-4F61-4B03-95B4-EFB598AA864DQ35115904-BD580185-56C9-4E4C-94B8-F11DF061CF45Q35236838-4D099503-F6EE-47C7-A00C-EF3DC058BF3FQ35311113-6BC96EEA-8991-4CC4-B764-9F8407CEB0E4Q35709581-316BA23F-A8BF-43FF-BFC8-777B41F6EEECQ35975429-44129198-FDBE-4E71-AB11-811AF7721D6BQ36000134-714C9AC0-B28E-4DD0-9C45-C06885559362Q36045282-0AE4167A-F0B7-4CDA-8C5C-2177C19A96F3Q36117914-89332080-A0EC-4F98-B7B4-EA0AF5D738CFQ36168470-75180814-4911-44A7-A5C1-18C75613EC93Q36252166-7E8DA423-25D8-4AB6-B1FB-882175D99F0D
P2860
Highly conserved and disease-specific patterns of carboxyterminally truncated Abeta peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation.
description
2002 nî lūn-bûn
@nan
2002 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Highly conserved and disease-s ...... ith chronic neuroinflammation.
@ast
Highly conserved and disease-s ...... ith chronic neuroinflammation.
@en
type
label
Highly conserved and disease-s ...... ith chronic neuroinflammation.
@ast
Highly conserved and disease-s ...... ith chronic neuroinflammation.
@en
prefLabel
Highly conserved and disease-s ...... ith chronic neuroinflammation.
@ast
Highly conserved and disease-s ...... ith chronic neuroinflammation.
@en
P2093
P2860
P921
P1476
Highly conserved and disease-s ...... with chronic neuroinflammation
@en
P2093
H Esselmann
H-W Klafki
M Beyermann
P2860
P304
P356
10.1046/J.1471-4159.2002.00818.X
P407
P577
2002-05-01T00:00:00Z