FTO levels affect RNA modification and the transcriptome - Wikidata - wikimedia - TriplyDB

FTO levels affect RNA modification and the transcriptome

FTO levels affect RNA modification and the transcriptome

http://www.wikidata.org/entity/Q31080924

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Important Role of FTO in the Survival of Rare Panresistant Triple-Negative Inflammatory Breast Cancer Cells Facing a Severe Metabolic Challenge NSUN3 and ABH1 modify the wobble position of mt-tRNAMet to expand codon recognition in mitochondrial translation Changes in gene expression associated with FTO overexpression in mice.Highly adaptable triple-negative breast cancer cells as a functional model for testing anticancer agents.FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis.N6-methyl-adenosine (m6A) in RNA: an old modification with a novel epigenetic function.N6-adenosine methylation in MiRNAs.Pharmacological inhibition of FTO.Urinary biomarker and treatment mechanism of Rhizoma Alismatis on hyperlipidemia.Nucleocytoplasmic Shuttling of FTO Does Not Affect Starvation-Induced Autophagy.FTO modulates fibrogenic responses in obstructive nephropathy.What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer.A patient with a novel homozygous missense mutation in FTO and concomitant nonsense mutation in CETP.Mouse Maternal High-Fat Intake Dynamically Programmed mRNA m⁶A Modifications in Adipose and Skeletal Muscle Tissues in Offspring.FTO and obesity: mechanisms of association.The 'Fat Mass and Obesity Related' (FTO) gene: Mechanisms of Impact on Obesity and Energy Balance.Prolyl hydroxylase domain enzymes: important regulators of cancer metabolism.Body mass index mediates the prognostic significance of circulating tumor cells in inflammatory breast cancer.CCAAT/enhancer-binding protein α is a crucial regulator of human fat mass and obesity associated gene transcription and expression.Differences in body mass index according to fat mass- and obesity-associated (FTO) genotype in Mexican patients with bipolar disorder.The impact of probiotic supplementation during pregnancy on DNA methylation of obesity-related genes in mothers and their children.

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FTO levels affect RNA modification and the transcriptome

http://www.wikidata.org/entity/Q31080924

description

2012 nî lūn-bûn

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2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի օգոստոսին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

FTO levels affect RNA modification and the transcriptome

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FTO levels affect RNA modification and the transcriptome

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FTO levels affect RNA modification and the transcriptome

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FTO levels affect RNA modification and the transcriptome

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FTO levels affect RNA modification and the transcriptome

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FTO levels affect RNA modification and the transcriptome

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European Journal of Human Genetics

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FTO levels affect RNA modification and the transcriptome

@en

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Bernhard Horsthemke

http://www.w3.org/2001/XMLSchema#string

Emil Mladenov

http://www.w3.org/2001/XMLSchema#string

Jürgen Thomale

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Ludger Klein-Hitpass

http://www.w3.org/2001/XMLSchema#string

Matthias Ziehe

http://www.w3.org/2001/XMLSchema#string

Tea Berulava

http://www.w3.org/2001/XMLSchema#string

Ulrich Rüther

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P2860

N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation

The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase

Crystal structure of the FTO protein reveals basis for its substrate specificity

Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

Comprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codons

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

Functional and Structural Impact of Target Uridine Substitutions on the H/ACA Ribonucleoprotein Particle Pseudouridine Synthase,

Inactivation of the Fto gene protects from obesity

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317-323

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scholarly article

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10.1038/EJHG.2012.168

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3

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21

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2012-08-08T00:00:00Z

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230632624

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1022819282

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22872099

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3573201

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