Unique base-step recognition by a platinum-acridinylthiourea conjugate leads to a DNA damage profile complementary to that of the anticancer drug cisplatin.
about
Characterization of the bisintercalative DNA binding mode of a bifunctional platinum-acridine agentComparative chemogenomics to examine the mechanism of action of dna-targeted platinum-acridine anticancer agentsProbing platinum-adenine-n3 adduct formation with DNA minor-groove binding agentsRates of intercalator-driven platination of DNA determined by a restriction enzyme cleavage inhibition assay.Replacement of a thiourea with an amidine group in a monofunctional platinum-acridine antitumor agent. Effect on DNA interactions, DNA adduct recognition and repair.Replacement of a thiourea-S with an amidine-NH donor group in a platinum-acridine antitumor compound reduces the metal's reactivity with cysteine sulfurA non-cross-linking platinum-acridine agent with potent activity in non-small-cell lung cancer.A review on acridinylthioureas and its derivatives: biological and cytotoxic activity.Nucleotide Binding Preference of the Monofunctional Platinum Anticancer-Agent Phenanthriplatin.
P2860
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P2860
Unique base-step recognition by a platinum-acridinylthiourea conjugate leads to a DNA damage profile complementary to that of the anticancer drug cisplatin.
description
2004 nî lūn-bûn
@nan
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Unique base-step recognition b ...... the anticancer drug cisplatin.
@ast
Unique base-step recognition b ...... the anticancer drug cisplatin.
@en
type
label
Unique base-step recognition b ...... the anticancer drug cisplatin.
@ast
Unique base-step recognition b ...... the anticancer drug cisplatin.
@en
prefLabel
Unique base-step recognition b ...... the anticancer drug cisplatin.
@ast
Unique base-step recognition b ...... the anticancer drug cisplatin.
@en
P2093
P356
P1433
P1476
Unique base-step recognition b ...... the anticancer drug cisplatin.
@en
P2093
Michael E Budiman
Rebecca W Alexander
Ulrich Bierbach
P304
P356
10.1021/BI049415D
P407
P577
2004-07-01T00:00:00Z