Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase. - Wikidata - wikimedia - TriplyDB

Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase.

Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase.

http://www.wikidata.org/entity/Q31093400

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Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom)Histone H4 lysine 91 acetylation a core domain modification associated with chromatin assembly Structure of the Neurospora SET domain protein DIM-5, a histone H3 lysine methyltransferase The many faces of histone H3K79 methylation Targeting histone methyltransferases and demethylases in clinical trials for cancer therapy Synthesis of lysine methyltransferase inhibitors Implication of posttranslational histone modifications in nucleotide excision repair The BAH domain of Rsc2 is a histone H3 binding domain N-alpha-terminal acetylation of histone H4 regulates arginine methylation and ribosomal DNA silencing Multiple histone modifications in euchromatin promote heterochromatin formation by redundant mechanisms in Saccharomyces cerevisiae.Regulation of NuA4 histone acetyltransferase activity in transcription and DNA repair by phosphorylation of histone H4.Interplay of chromatin modifiers on a short basic patch of histone H4 tail defines the boundary of telomeric heterochromatin Yeast Hmt1 catalyses asymmetric dimethylation of histone H3 arginine 2 in vitro.Rmt1 catalyzes zinc-finger independent arginine methylation of ribosomal protein Rps2 in Saccharomyces cerevisiae.The Yng1p plant homeodomain finger is a methyl-histone binding module that recognizes lysine 4-methylated histone H3.The yeast SR-like protein Npl3 links chromatin modification to mRNA processing Proteomic analysis of interactors for yeast protein arginine methyltransferase Hmt1 reveals novel substrate and insights into additional biological roles.Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA damage checkpoint functions of Rad9.Identification of histone demethylases in Saccharomyces cerevisiae.The Rtf1 component of the Paf1 transcriptional elongation complex is required for ubiquitination of histone H2B.Noncompetitive counteractions of DNA polymerase epsilon and ISW2/yCHRAC for epigenetic inheritance of telomere position effect in Saccharomyces cerevisiae A charge-based interaction between histone H4 and Dot1 is required for H3K79 methylation and telomere silencing: identification of a new trans-histone pathway The role of protein arginine methylation in the formation of silent chromatin Methylation of histone H3 on lysine 79 associates with a group of replication origins and helps limit DNA replication once per cell cycle Competition between Heterochromatic Loci Allows the Abundance of the Silencing Protein, Sir4, to Regulate de novo Assembly of Heterochromatin.The Nuts and Bolts of Transcriptionally Silent Chromatin in Saccharomyces cerevisiae.Quantitative proteomic analysis of histone modifications Regulation of the DNA damage response and gene expression by the Dot1L histone methyltransferase and the 53Bp1 tumour suppressor Insights into the role of histone H3 and histone H4 core modifiable residues in Saccharomyces cerevisiae.Chromatin modifications as therapeutic targets in MLL-rearranged leukemia.CREB trans-activation of disruptor of telomeric silencing-1 mediates forskolin inhibition of CTGF transcription in mesangial cells.Allele-specific H3K79 Di- versus trimethylation distinguishes opposite parental alleles at imprinted regions Ubp10/Dot4p regulates the persistence of ubiquitinated histone H2B: distinct roles in telomeric silencing and general chromatin.A medicinal chemistry perspective for targeting histone H3 lysine-79 methyltransferase DOT1L.Deficiency in Bre1 impairs homologous recombination repair and cell cycle checkpoint response to radiation damage in mammalian cells Recruitment of Rpd3 to the telomere depends on the protein arginine methyltransferase Hmt1.H2A.Z (Htz1) controls the cell-cycle-dependent establishment of transcriptional silencing at Saccharomyces cerevisiae telomeres.Genomic insights of protein arginine methyltransferase Hmt1 binding reveals novel regulatory functions The tale beyond the tail: histone core domain modifications and the regulation of chromatin structure DOT1L regulates dystrophin expression and is critical for cardiac function.

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P2860

Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase.

http://www.wikidata.org/entity/Q31093400

description

2002 nî lūn-bûn

@nan

2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի հուլիսին հրատարակված գիտական հոդված

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2002年の論文

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2002年学术文章

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2002年学术文章

@zh-cn

2002年学术文章

@zh-hans

2002年学术文章

@zh-my

2002年学术文章

@zh-sg

2002年學術文章

@yue

name

Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase.

@ast

Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase.

@en

type

label

Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase.

@ast

Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase.

@en

prefLabel

Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase.

@ast

Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase.

@en

P1433

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P2860

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P1433

Journal of Biological Chemistry

P1476

Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase

@en

P2093

Guy G Poirier

http://www.w3.org/2001/XMLSchema#string

Joanna M Hunter

http://www.w3.org/2001/XMLSchema#string

Nicolas Lacoste

http://www.w3.org/2001/XMLSchema#string

Rhea T Utley

http://www.w3.org/2001/XMLSchema#string

P2860

Translating the Histone Code

Crystal structure of the nucleosome core particle at 2.8 A resolution

NuA4, an essential transcription adaptor/histone H4 acetyltransferase complex containing Esa1p and the ATM-related cofactor Tra1p

Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression.

Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association

The structure and oligomerization of the yeast arginine methyltransferase, Hmt1

Histone H3 specific acetyltransferases are essential for cell cycle progression.

A novel methyltransferase (Hmt1p) modifies poly(A)+-RNA-binding proteins.

The predominant protein-arginine methyltransferase from Saccharomyces cerevisiae.

Role for the silencing protein Dot1 in meiotic checkpoint control.

P304

30421-30424

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scholarly article

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10.1074/JBC.C200366200

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P433

34

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P478

277

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2002-07-03T00:00:00Z

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11279334

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12097318

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