Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase.
about
Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom)Histone H4 lysine 91 acetylation a core domain modification associated with chromatin assemblyStructure of the Neurospora SET domain protein DIM-5, a histone H3 lysine methyltransferaseThe many faces of histone H3K79 methylationTargeting histone methyltransferases and demethylases in clinical trials for cancer therapySynthesis of lysine methyltransferase inhibitorsImplication of posttranslational histone modifications in nucleotide excision repairThe BAH domain of Rsc2 is a histone H3 binding domainN-alpha-terminal acetylation of histone H4 regulates arginine methylation and ribosomal DNA silencingMultiple histone modifications in euchromatin promote heterochromatin formation by redundant mechanisms in Saccharomyces cerevisiae.Regulation of NuA4 histone acetyltransferase activity in transcription and DNA repair by phosphorylation of histone H4.Interplay of chromatin modifiers on a short basic patch of histone H4 tail defines the boundary of telomeric heterochromatinYeast Hmt1 catalyses asymmetric dimethylation of histone H3 arginine 2 in vitro.Rmt1 catalyzes zinc-finger independent arginine methylation of ribosomal protein Rps2 in Saccharomyces cerevisiae.The Yng1p plant homeodomain finger is a methyl-histone binding module that recognizes lysine 4-methylated histone H3.The yeast SR-like protein Npl3 links chromatin modification to mRNA processingProteomic analysis of interactors for yeast protein arginine methyltransferase Hmt1 reveals novel substrate and insights into additional biological roles.Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA damage checkpoint functions of Rad9.Identification of histone demethylases in Saccharomyces cerevisiae.The Rtf1 component of the Paf1 transcriptional elongation complex is required for ubiquitination of histone H2B.Noncompetitive counteractions of DNA polymerase epsilon and ISW2/yCHRAC for epigenetic inheritance of telomere position effect in Saccharomyces cerevisiaeA charge-based interaction between histone H4 and Dot1 is required for H3K79 methylation and telomere silencing: identification of a new trans-histone pathwayThe role of protein arginine methylation in the formation of silent chromatinMethylation of histone H3 on lysine 79 associates with a group of replication origins and helps limit DNA replication once per cell cycleCompetition between Heterochromatic Loci Allows the Abundance of the Silencing Protein, Sir4, to Regulate de novo Assembly of Heterochromatin.The Nuts and Bolts of Transcriptionally Silent Chromatin in Saccharomyces cerevisiae.Quantitative proteomic analysis of histone modificationsRegulation of the DNA damage response and gene expression by the Dot1L histone methyltransferase and the 53Bp1 tumour suppressorInsights into the role of histone H3 and histone H4 core modifiable residues in Saccharomyces cerevisiae.Chromatin modifications as therapeutic targets in MLL-rearranged leukemia.CREB trans-activation of disruptor of telomeric silencing-1 mediates forskolin inhibition of CTGF transcription in mesangial cells.Allele-specific H3K79 Di- versus trimethylation distinguishes opposite parental alleles at imprinted regionsUbp10/Dot4p regulates the persistence of ubiquitinated histone H2B: distinct roles in telomeric silencing and general chromatin.A medicinal chemistry perspective for targeting histone H3 lysine-79 methyltransferase DOT1L.Deficiency in Bre1 impairs homologous recombination repair and cell cycle checkpoint response to radiation damage in mammalian cellsRecruitment of Rpd3 to the telomere depends on the protein arginine methyltransferase Hmt1.H2A.Z (Htz1) controls the cell-cycle-dependent establishment of transcriptional silencing at Saccharomyces cerevisiae telomeres.Genomic insights of protein arginine methyltransferase Hmt1 binding reveals novel regulatory functionsThe tale beyond the tail: histone core domain modifications and the regulation of chromatin structureDOT1L regulates dystrophin expression and is critical for cardiac function.
P2860
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P2860
Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
name
Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase.
@ast
Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase.
@en
type
label
Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase.
@ast
Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase.
@en
prefLabel
Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase.
@ast
Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase.
@en
P2093
P2860
P356
P1476
Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase
@en
P2093
Guy G Poirier
Joanna M Hunter
Nicolas Lacoste
Rhea T Utley
P2860
P304
30421-30424
P356
10.1074/JBC.C200366200
P407
P50
P577
2002-07-03T00:00:00Z