Dissection of the recognition properties of p38 MAP kinase. Determination of the binding mode of a new pyridinyl-heterocycle inhibitor family.
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Rapid flexible docking using a stochastic rotamer library of ligandsDiscrete molecular dynamics distinguishes nativelike binding poses from decoys in difficult targets.A potent and selective p38 inhibitor protects against bone damage in murine collagen-induced arthritis: a comparison with neutralization of mouse TNFalpha.Target flexibility: an emerging consideration in drug discovery and design.Use of p38 MAPK Inhibitors for the Treatment of Werner Syndrome.Synthesis of the highly selective p38 MAPK inhibitor UR-13756 for possible therapeutic use in Werner syndrome.Consistent improvement of cross-docking results using binding site ensembles generated with elastic network normal modes.
P2860
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P2860
Dissection of the recognition properties of p38 MAP kinase. Determination of the binding mode of a new pyridinyl-heterocycle inhibitor family.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
name
Dissection of the recognition ...... -heterocycle inhibitor family.
@ast
Dissection of the recognition ...... -heterocycle inhibitor family.
@en
type
label
Dissection of the recognition ...... -heterocycle inhibitor family.
@ast
Dissection of the recognition ...... -heterocycle inhibitor family.
@en
prefLabel
Dissection of the recognition ...... -heterocycle inhibitor family.
@ast
Dissection of the recognition ...... -heterocycle inhibitor family.
@en
P2093
P356
P1476
Dissection of the recognition ...... -heterocycle inhibitor family.
@en
P2093
Carmen Almansa
Marina Virgili
Modesto Orozco
Robert Soliva
P304
P356
10.1021/JM061073H
P407
P577
2007-01-01T00:00:00Z