Ku70 suppresses the apoptotic translocation of Bax to mitochondria.
about
Interaction with a membrane surface triggers a reversible conformational change in Bax normally associated with induction of apoptosisASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathwayClusterin inhibits apoptosis by interacting with activated BaxLoss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosisSIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70Non-homologous end joining, but not homologous recombination, enables survival for cells exposed to a histone deacetylase inhibitor.Sirtuins in Cancer: a Balancing Act between Genome Stability and MetabolismMicroarray Analysis Reveals Increased Transcriptional Repression and Reduced Metabolic Activity but Not Major Changes in the Core Apoptotic Machinery during Maturation of Sympathetic Neurons.Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) Has a Unique Mechanism to Rescue Apoptotic NeuronsA newly identified essential complex, Dre2-Tah18, controls mitochondria integrity and cell death after oxidative stress in yeast.A TSC22-like motif defines a novel antiapoptotic protein family.Old yellow enzymes, highly homologous FMN oxidoreductases with modulating roles in oxidative stress and programmed cell death in yeast.SIRT1 and LSD1 competitively regulate KU70 functions in DNA repair and mutation acquisition in cancer cellsThe lysosome-associated apoptosis-inducing protein containing the pleckstrin homology (PH) and FYVE domains (LAPF), representative of a novel family of PH and FYVE domain-containing proteins, induces caspase-independent apoptosis via the lysosomal-mThe intersection between DNA damage response and cell death pathwaysDNA-binding protects p53 from interactions with cofactors involved in transcription-independent functions.Use of phage display to identify novel mineralocorticoid receptor-interacting proteins.USP22 Induces Cisplatin Resistance in Lung Adenocarcinoma by Regulating γH2AX-Mediated DNA Damage Repair and Ku70/Bax-Mediated ApoptosisEffect of Ku70 expression on radiosensitivity in renal carcinoma 786-O cells.Inhibition of adenine nucleotide translocator pore function and protection against apoptosis in vivo by an HIV protease inhibitorKu70 acetylation mediates neuroblastoma cell death induced by histone deacetylase inhibitors.Recombinant VP1, an Akt inhibitor, suppresses progression of hepatocellular carcinoma by inducing apoptosis and modulation of CCL2 productionP53 inhibition exacerbates late-stage anthracycline cardiotoxicity.Neuronal apoptosis in cerebral ischemia/reperfusion area following electrical stimulation of fastigial nucleusLipopolysaccharide protects primary B lymphocytes from apoptosis by preventing mitochondrial dysfunction and bax translocation to mitochondriaSmall-molecule Bax agonists for cancer therapy.The domains of apoptosis: a genomics perspective.Visualization of inositol phosphate-dependent mobility of Ku: depletion of the DNA-PK cofactor InsP6 inhibits Ku mobility.Histone deacetylase 9 (HDAC9) regulates the functions of the ATDC (TRIM29) protein.Regulated cell death in AKI.CLU blocks HDACI-mediated killing of neuroblastoma.Granzyme A, which causes single-stranded DNA damage, targets the double-strand break repair protein Ku70.Transcription-coupled DNA double-strand breaks are mediated via the nucleotide excision repair and the Mre11-Rad50-Nbs1 complexEndosome-mitochondria juxtaposition during apoptosis induced by H. pylori VacAPathways for ischemic cytoprotection: role of sirtuins in caloric restriction, resveratrol, and ischemic preconditioning.Sorting out functions of sirtuins in cancerMalignant T cells in cutaneous T-cell lymphoma lesions contain decreased levels of the antiapoptotic protein Ku70KAP1 Deacetylation by SIRT1 Promotes Non-Homologous End-Joining RepairMitochondria: a target for cancer therapy.The Bcl-2 family: roles in cell survival and oncogenesis.
P2860
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P2860
Ku70 suppresses the apoptotic translocation of Bax to mitochondria.
description
2003 nî lūn-bûn
@nan
2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Ku70 suppresses the apoptotic translocation of Bax to mitochondria.
@ast
Ku70 suppresses the apoptotic translocation of Bax to mitochondria.
@en
type
label
Ku70 suppresses the apoptotic translocation of Bax to mitochondria.
@ast
Ku70 suppresses the apoptotic translocation of Bax to mitochondria.
@en
prefLabel
Ku70 suppresses the apoptotic translocation of Bax to mitochondria.
@ast
Ku70 suppresses the apoptotic translocation of Bax to mitochondria.
@en
P2093
P356
P1433
P1476
Ku70 suppresses the apoptotic translocation of Bax to mitochondria
@en
P2093
Konstantin Leskov
Motoshi Sawada
Paulette Hayes
Shigemi Matsuyama
Weiyong Sun
P2888
P304
P356
10.1038/NCB950
P577
2003-04-01T00:00:00Z
P6179
1036115088