Quantification of protein-ligand interactions by mass spectrometry, titration, and H/D exchange: PLIMSTEX.
about
Autoproteolytic fragments are intermediates in the oligomerization/aggregation of the Parkinson's disease protein alpha-synuclein as revealed by ion mobility mass spectrometryHydrogen exchange mass spectrometry: are we out of the quicksand?Laser flash photolysis of hydrogen peroxide to oxidize protein solvent-accessible residues on the microsecond timescale.Type 1 and Type 2 scenarios in hydrogen exchange mass spectrometry studies on protein-ligand complexes.Integrated algorithms for high-throughput examination of covalently labeled biomolecules by structural mass spectrometry.Mass spectrometry-based carboxyl footprinting of proteins: method evaluation.Integrating mass spectrometry of intact protein complexes into structural proteomicsPeptide-column interactions and their influence on back exchange rates in hydrogen/deuterium exchange-MS.Modeling data from titration, amide H/D exchange, and mass spectrometry to obtain protein-ligand binding constants.Mass spectrometry-based approaches to protein-ligand interactions.The calcium-modulated structures of calmodulin and S100b proteins are useful to monitor hydrogen/deuterium exchange efficiency using matrix-assisted laser desorption ionization time-of-flight mass spectrometry.Cold chemical oxidation of proteins.Picosecond-resolved fluorescent probes at functionally distinct tryptophans within a thermophilic alcohol dehydrogenase: relationship of temperature-dependent changes in fluorescence to catalysis.Fast photochemical oxidation of proteins for comparing structures of protein-ligand complexes: the calmodulin-peptide model system.Elucidation of the binding sites of sodium dodecyl sulfate to β-lactoglobulin using hydrogen/deuterium exchange mass spectrometry combined with docking simulation.Kinetic capillary electrophoresis with mass-spectrometry detection (KCE-MS) facilitates label-free solution-based kinetic analysis of protein-small molecule binding.Protein-peptide affinity determination using an h/d exchange dilution strategy: application to antigen-antibody interactionsComparison of Two ESI MS Based H/D Exchange Methods for Extracting Protein Folding Energies.Stable isotope labeling strategy for protein-ligand binding analysis in multi-component protein mixtures.Carboxyl-group footprinting maps the dimerization interface and phosphorylation-induced conformational changes of a membrane-associated tyrosine kinase.Differential hydrogen/deuterium exchange mass spectrometry analysis of protein-ligand interactionsHydrophobic Peptides Affect Binding of Calmodulin and Ca as Explored by H/D Amide Exchange and Mass Spectrometry.Quantifying non-covalent binding affinity using mass spectrometry: a systematic study on complexes of cyclodextrins with alkali metal cations.Slow histidine H/D exchange protocol for thermodynamic analysis of protein folding and stability using mass spectrometry.Quantitative MALDI-MS Binding Assays: An Alternative to Radiolabeling.Distinct mechanisms of calmodulin binding and regulation of adenylyl cyclases 1 and 8Theory of the Protein Equilibrium Population Snapshot by H/D Exchange Electrospray Ionization Mass Spectrometry (PEPS-HDX-ESI-MS) Method used to obtain Protein Folding Energies/Rates and Selected Supporting Experimental Evidence.Strong anion exchange for studying protein-DNA interactions by H/D exchange mass spectrometry.Kinetics of Protein Complex Dissociation Studied by Hydrogen/Deuterium Exchange and Mass Spectrometry.Membrane orientation of the FMO antenna protein from Chlorobaculum tepidum as determined by mass spectrometry-based footprinting.Unraveling the dynamics of protein interactions with quantitative mass spectrometry.Mass spectrometry based tools to investigate protein-ligand interactions for drug discovery.Characterization of noncovalent protein-ligand complexes and associated enzyme intermediates of GlcNAc-6-O-sulfotransferase by electrospray ionization FT-ICR mass spectrometry.Painting proteins with covalent labels: what's in the picture?Emerging Methods in Chemoproteomics with Relevance to Drug Discovery.Conformational characterization of the intrinsically disordered protein Chibby: Interplay between structural elements in target recognition.Determination of Noncovalent Binding Using a Continuous Stirred Tank Reactor as a Flow Injection Device Coupled to Electrospray Ionization Mass Spectrometry.HD exchange and PLIMSTEX determine the affinities and order of binding of Ca2+ with troponin C.Probing protein surface with a solvent mimetic carbene coupled to detection by mass spectrometry.Peptide-Level Interactions between Proteins and Small-Molecule Drug Candidates by Two Hydrogen-Deuterium Exchange MS-Based Methods: The Example of Apolipoprotein E3.
P2860
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P2860
Quantification of protein-ligand interactions by mass spectrometry, titration, and H/D exchange: PLIMSTEX.
description
2003 nî lūn-bûn
@nan
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Quantification of protein-liga ...... n, and H/D exchange: PLIMSTEX.
@ast
Quantification of protein-liga ...... n, and H/D exchange: PLIMSTEX.
@en
type
label
Quantification of protein-liga ...... n, and H/D exchange: PLIMSTEX.
@ast
Quantification of protein-liga ...... n, and H/D exchange: PLIMSTEX.
@en
prefLabel
Quantification of protein-liga ...... n, and H/D exchange: PLIMSTEX.
@ast
Quantification of protein-liga ...... n, and H/D exchange: PLIMSTEX.
@en
P2093
P356
P1476
Quantification of protein-liga ...... n, and H/D exchange: PLIMSTEX.
@en
P2093
Don L Rempel
Michael L Gross
Zhaohui Du
P304
P356
10.1021/JA029460D
P407
P577
2003-05-01T00:00:00Z