New synthetic seven-membered 1-azasugars displaying potent inhibition towards glycosidases and glucosylceramide transferase.
about
Binding of 3,4,5,6-Tetrahydroxyazepanes to the Acid-β-glucosidase Active Site: Implications for Pharmacological Chaperone Design for Gaucher DiseaseCrystal structure of (4R,5S,6R)-6-azido-5-benz-yloxy-3,3,4-tri-fluoro-azepan-1-ium 2,2,2-tri-fluoro-acetate from synchrotron data.Selection of the biological activity of DNJ neoglycoconjugates through click length variation of the side chain.Identification of potent and selective glucosylceramide synthase inhibitors from a library of N-alkylated iminosugars.N- and C-alkylation of seven-membered iminosugars generates potent glucocerebrosidase inhibitors and F508del-CFTR correctors.Glycosphingolipids--nature, function, and pharmacological modulation.Metathesis access to monocyclic iminocyclitol-based therapeutic agents.Synthesis and evaluation of eight- and four-membered iminosugar analogues as inhibitors of testicular ceramide-specific glucosyltransferase, testicular β-glucosidase 2, and other glycosidases.Structure-Activity Studies of N-Butyl-1-deoxynojirimycin (NB-DNJ) Analogues: Discovery of Potent and Selective Aminocyclopentitol Inhibitors of GBA1 and GBA2.Conformational regulation of substituted azepanes through selective monofluorination.
P2860
Q27675348-17E3EB12-731B-42CF-86EC-4C5CA0E6C138Q31027235-EA575FDE-15A7-4ED4-B1AD-ECBC200FBB95Q33879577-50572267-7F42-4D32-9F33-14F42B0C61D1Q35181892-4891391A-3BCD-4FCD-B1CB-3931C9897E26Q35296367-C8DF0BB1-EE41-4918-B4ED-643DE3490866Q37622816-3BC8322E-92FD-4A6A-918C-3EEB70E59E49Q37909033-751FC8AE-6AEA-4507-85A6-B54D9852EDACQ42322397-A995669E-9D36-4A47-81BA-A50707F6378AQ47094962-D69FD803-CC1F-4C26-BFBE-887B5807D95BQ53119099-9BA80B81-1F46-4CD0-8EAA-F83D6D9F289D
P2860
New synthetic seven-membered 1-azasugars displaying potent inhibition towards glycosidases and glucosylceramide transferase.
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
New synthetic seven-membered 1 ...... glucosylceramide transferase.
@ast
New synthetic seven-membered 1 ...... glucosylceramide transferase.
@en
type
label
New synthetic seven-membered 1 ...... glucosylceramide transferase.
@ast
New synthetic seven-membered 1 ...... glucosylceramide transferase.
@en
prefLabel
New synthetic seven-membered 1 ...... glucosylceramide transferase.
@ast
New synthetic seven-membered 1 ...... glucosylceramide transferase.
@en
P2093
P2860
P356
P1433
P1476
New synthetic seven-membered 1 ...... d glucosylceramide transferase
@en
P2093
Hongqing Li
Jérôme Marrot
Nikos G Oikonomakos
Pierre Vogel
Sylvain Favre
Terry D Butters
Yongmin Zhang
Yves Blériot
P2860
P304
P356
10.1002/CBIC.200700496
P577
2008-01-01T00:00:00Z