Model structures of alpha-2 adrenoceptors in complex with automatically docked antagonist ligands raise the possibility of interactions dissimilar from agonist ligands.

Model structures of alpha-2 adrenoceptors in complex with automatically docked antagonist ligands raise the possibility of interactions dissimilar from agonist ligands.

Item
http://www.wikidata.org/entity/Q31167652
Potential modes of interaction of 9-aminomethyl-9,10-dihydroanthracene (AMDA) derivatives with the 5-HT2A receptor: a ligand structure-affinity relationship, receptor mutagenesis and receptor modeling investigationStructure and dynamics of DRD4 bound to an agonist and an antagonist using in silico approaches.CoMFA analyses of C-2 position salvinorin A analogs at the kappa-opioid receptor provides insights into epimer selectivity.Design, synthesis, and biological evaluation of 6alpha- and 6beta-N-heterocyclic substituted naltrexamine derivatives as mu opioid receptor selective antagonists.Binding of serotonin and N1-benzenesulfonyltryptamine-related analogs at human 5-HT6 serotonin receptors: receptor modeling studies.Conserved structural, pharmacological and functional properties among the three human and five zebrafish alpha 2-adrenoceptorsModeling of the OX1R-orexin-A complex suggests two alternative binding modes.The second extracellular loop of alpha2A-adrenoceptors contributes to the binding of yohimbine analoguesInvolvement of the first transmembrane segment of human α(2) -adrenoceptors in the subtype-selective binding of chlorpromazine, spiperone and spiroxatrine.Synthesis, structure-affinity relationships, and modeling of AMDA analogs at 5-HT2A and H1 receptors: structural factors contributing to selectivity.Synthesis and biological evaluation of N-arylpiperazine derivatives of 4,4-dimethylisoquinoline-1,3(2H,4H)-dione as potential antiplatelet agents.
P2860

Model structures of alpha-2 adrenoceptors in complex with automatically docked antagonist ligands raise the possibility of interactions dissimilar from agonist ligands.

Item
http://www.wikidata.org/entity/Q31167652
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
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2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
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name
Model structures of alpha-2 ad ...... ssimilar from agonist ligands.
@ast
Model structures of alpha-2 ad ...... ssimilar from agonist ligands.
@en
type
label
Model structures of alpha-2 ad ...... ssimilar from agonist ligands.
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Model structures of alpha-2 ad ...... ssimilar from agonist ligands.
@en
prefLabel
Model structures of alpha-2 ad ...... ssimilar from agonist ligands.
@ast
Model structures of alpha-2 ad ...... ssimilar from agonist ligands.
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P1433
P1476
P2093
P304
P31
P356
P433
P478
P50
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P921
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P1433
P1476
Model structures of alpha-2 ad ...... ssimilar from agonist ligands.
@en
P2093
P304
P31
P356
P433
P478
P50
P577
P698
P921