Synthesis and evaluation of "AZT-HEPT", "AZT-pyridinone", and "ddC-HEPT" conjugates as inhibitors of HIV reverse transcriptase.

Synthesis and evaluation of "AZT-HEPT", "AZT-pyridinone", and "ddC-HEPT" conjugates as inhibitors of HIV reverse transcriptase.

Item
http://www.wikidata.org/entity/Q31383931
Design, Synthesis, and Antiviral Evaluation of Chimeric Inhibitors of HIV Reverse Transcriptase.[d4U]-spacer-[HI-236] double-drug inhibitors of HIV-1 reverse-transcriptase.A new antiviral: chimeric 3TC-AZT phosphonate efficiently inhibits HIV-1 in human tissues ex vivo.Fluorous 2,4-Dichloro-1,3,5-triazine (F-DCT) as Amide Coupling Agent.Fluorous 2,4-Dichloro-1,3,5-triazines (F-DCTs) as Nucleophile ScavengersBifunctional inhibition of HIV-1 reverse transcriptase: a first step in designing a bifunctional triphosphate.C-2-aryl O-substituted HI-236 derivatives as non-nucleoside HIV-1 reverse-transcriptase inhibitors.Dual-targeted anti-TB/anti-HIV heterodimers.Structure-activity relationship studies on a novel family of specific HIV-1 reverse transcriptase inhibitors.Symmetrical and unsymmetrical alpha,omega-nucleobase amide-conjugated systems.Bifunctional inhibition of human immunodeficiency virus type 1 reverse transcriptase: mechanism and proof-of-concept as a novel therapeutic design strategy.Synthesis and anti-HIV activity of [d4U]-[trovirdine analogue] and [d4T]-[trovirdine analogue] heterodimers as inhibitors of HIV-1 reverse transcriptase.Studies on the inhibition of Moloney murine leukemia virus reverse transcriptase by N-tritylamino acids and N-tritylamino acid-nucleotide compounds.Novel acyclic amide-conjugated nucleosides and their analogues.Antiviral activity of 4-benzyl pyridinone derivatives as HIV-1 reverse transcriptase inhibitors.Conjugation of phosphonoacetic acid to nucleobase promotes a mechanism-based inhibition.Identification of novel bifunctional HIV-1 reverse transcriptase inhibitors.
P2860

Synthesis and evaluation of "AZT-HEPT", "AZT-pyridinone", and "ddC-HEPT" conjugates as inhibitors of HIV reverse transcriptase.

Item
http://www.wikidata.org/entity/Q31383931
description
2000 nî lūn-bûn
@nan
2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
name
Synthesis and evaluation of "A ...... of HIV reverse transcriptase.
@ast
Synthesis and evaluation of "A ...... of HIV reverse transcriptase.
@en
type
label
Synthesis and evaluation of "A ...... of HIV reverse transcriptase.
@ast
Synthesis and evaluation of "A ...... of HIV reverse transcriptase.
@en
prefLabel
Synthesis and evaluation of "A ...... of HIV reverse transcriptase.
@ast
Synthesis and evaluation of "A ...... of HIV reverse transcriptase.
@en
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P356
P1433
P1476
Synthesis and evaluation of "A ...... of HIV reverse transcriptase.
@en
P2093
P304
P31
P356
P407
P433
P478
P577
P698